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As we previously demonstrated, there is an adaptive increase in insulin secretion in insulin resistance in the model of high-fat fed female mice. Since it is assumed that islets also adapt to insulin resistance with beta-cell expansion, we have now examined beta-cell volume in this experimental model. Female C57BL/6JBomTac mice were therefore fed a high-fat diet (60% fat from lard) for three, six
Objective. To determine whether a pharmacist-led medications review in primary care reduces the number of drugs and the number of drug-related problems. Design. Prospective randomized controlled trial. Setting. Liljeholmen Primary Care Centre, Stockholm, Sweden. Subjects. 209 patients aged ≥ 65 years with five or more different medications. Intervention. Patients answered a questionnaire regarding
Introducing a basis for further development of a risk-security model, this article discusses how such a model could be applied in an analysis of the area of youth employment. The article explores certain aspects of recent youth employment policies as expressed in union policies and in the national labour law of a number of EU Member States. Special attention is paid to national labour law reforms
The concept, design and prototype developments for the Lund-York-Cologne CAlorimeter (LYCCA) is presented. LYCCA is a modular device for the NUclear STructure, Astrophysics and Reactions (NUSTAR) science pillar of the Facility for Antiproton and Ion Research (FAIR) at Darmstadt, Germany. LYCCA is designed to discriminate heavy ions produced in nuclear reactions induced by relativistic radioactive
Aim: This study investigated the relationship between sexual debut before 14 years of age and socio-demographics, sexual experience, health, experience of child abuse and behaviour at 18 years of age. Methods: A sample of 3432 Swedish high school seniors completed a survey about sexuality, health and abuse at the age of 18. Results: Early debut was positively correlated with risky behaviours, such
Fluorescence diffuse optical tomography (FDOT) is a biomedical imaging modality that can be used for localization and quantification of fluorescent molecules inside turbid media. In this ill-posed problem, the reconstruction quality is directly determined by the amount and quality of the information obtained from the boundary measurements. Regularly, more information can be obtained by increasing
The Internet is a unique medium never before seen and its introduction is probably only rivalled by that of television. It is unique in the sense that every person connected to the Internet has the possibility of interacting with other people across the globe simultaneously. The tools introduced to facilitate this interaction are IP-addresses and domain names. Domain names are connected to the IP-
The purpose of this report is to evaluate the evacuation safety of Idrottens Hus in Helsingborg. The report is part of the educational programme of Fire Protection Engineering at Lund University. Idrottens Hus is a large sports center in downtown Helsingborg, Sweden. A number of likely fire scenarios were evaluated. For each scenario a design fire was created. The design fires were simulated in CF
Popular Abstract in Swedish I den här avhandlingen studeras de elektriska egenskaperna hos nanotrådar av halvledarmaterial. En halvledare är ett mellanting av en ledare och en isolator, där den elektriska ledningsförmågan kan styras både genom att förorena materialet med andra ämnen och genom att påverka materialet med ett elektriskt fält. I princip all modern elektronik bygger på komponenter av hThis thesis focuses on electron transport in semiconductor InAs/InP and InSb nanowire quantum devices. However, first the temperature dependence of classical charge transport in InSb nanowire field-effect transistors, FETs, is characterized, using InAs nanowire FETs as a reference. We find that the InSb FETs, in the same way as InAs FETs, are n-type with good current saturation and low voltage ope
This report on detailed aerosol characterization of fire smoke emissions is part of the Fire-Induced Radiological Integrated Assessment (FIRIA; CERN, Switzerland). In this study, carried out at Lund University, a number of materials were combusted in a cone calorimeter at varied heat fluxes. In a few experiments, the effect of reduced O2 content of supply air was investigated (vitiated conditions)
Recent studies demonstrate that Black Carbon (BC) pollution in economically developing megacities remain higher than the values, which the World Health Organization considers to be safe. Despite the scientific evidence of the degrees of BC exposure, there is still a lack of understanding on how the severe levels of BC pollution affect human health in these regions. We consider information on the r
Diabetes prone biobreeding rats display several abnormalites in T cell numbers, T cell function and T cell surface phenotype which are associated with the onset of spontaneous disease. One of the most pronounced abnormalities in these animals is a marked T cell lymphopenia which is evident in both CD4+ and CD8+ peripheral T cell subsets. To gain a better understanding as to the nature of T cell re
The present invention provides methods that increases the graft survival rate of pancreatic islets after pancreatic islet transplantation, maintains the survival of pancreatic islets ex vivo, and reduce the number of transplanted pancreatic islets required for normalizing blood glucose levels. When performing pancreatic islet transplantation, by pre-incubating pancreatic islets with stem cells or
The article argues that the digitally mediated and data-driven development stresses the need for socio-legal scrutiny. It focuses and briefly outline socio-legally relevant aspects of the “sharing” economy, that poses a number of conceptual issues on how we understand and regulate innovative platform based ventures. The article also underscores a number of issues relating to the role of consumer aIn this article we argue the need for more socio-legal scrutiny in a digitally mediated and data-driven development. We focus and briefly outline socio-legally relevant aspects of the “sharing” economy, that poses a number of conceptual issues on how we understand and regulate innovative platform based ventures. This also arguably underscores a number of issues relating to the role of consumer and
Given that public transportation networks are less developed in rural than in urban areas, a lack of accessibility to dental care facilities could be a barrier to routine dental checkups. Thus, we hypothesized that the distance to the dental care facilities is a risk factor for tooth loss. The aim of this study was to test whether there is an association between the distance to dental care facilit
Percutaneous implants have been associated with numerous problems. However, by using skin-penetrating, bone-anchored titanium implants, developed by Professor Branemark at the Department of Anatomy, University of Goteborg, good long-term results have been observed. These implants have been in clinical use for anchorage of bone-conducting hearing aids and facial prostheses since 1977 and 1979, resp
Systemic Lupus International Collaborating Clinics (SLICC) comprises 27 centres from 11 countries. An inception cohort of 918 SLE patients has been assembled according to a standardized protocol between 2000 and 2006. Clinical features, classic coronary artery disease (CAD) risk factors, as well as other potential risk factors were collected. Of the 918 patients 89% were females, and of multi raci
