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Background: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients with severe asthma eligible for both anti-IgE and anti-IL5/5R and to compare the effectiveness of both classes of treatment in real life. Methods: This was a prospective cohort s
We recently reported that female patients with hypopituitarism receiving controlled thyroid and steroid hormone substitution, but without GH replacement, had a more than 2-fold increase in cardiovascular mortality compared to the general population. In the present study we investigated the incidence of cardiovascular disease as well as the prevalence of cardiovascular risk factors in 33 females wi
Aim: The sweeping transformation of the biosphere by humans over the last millennia leaves only limited windows into its natural state. Much of the forests that dominated temperate and southern boreal regions have been lost and those that remain typically bear a strong imprint of forestry activities and past land-use change, which have changed forest age structure and composition. Here, we ask how
Avoidance maneuvers at normal driving speed or higher are demanding driving situations that force the vehicle to the limit of tire–road friction in critical situations. To study and develop control for these situations, dynamic optimization has been in growing use in research. One idea to handle such optimization computations effectively is to divide the total maneuver into a sequence of sub-maneu
OBJECTIVE: The aim of this study was to describe and present the outcomes of a specific treatment protocol for aortic vascular graft and endograft infections (VGEIs) without explantation of the infected graft.METHODS: This was a retrospective, observational single centre cohort study carried out between 2012 and 2022 at a tertiary hospital. An aortic VGEI was defined according to the Management of
Childhood stunting is a serious global public health issue that exhibits local spatial variations. Previous studies have used traditional statistical methods to identify stunting risk factors, and little is known about the application and usefulness of spatial machine learning techniques in identifying localized stunting risk factors based on complex datasets. This study assesses the performance o
AIMS: Diet is a determinant of cardiovascular diseases (CVD) with coronary disease as predominant cause of pre-mature death. To analyse how diet was associated with coronary atherosclerosis, including plaque features.METHODS AND RESULTS: The cross-sectional population-based study using data from the Swedish CArdioPulmonary BioImage Study (SCAPIS) included 24 079 adults aged 50-64 years, recruited
Long-term population studies can identify changes in population dynamics over time. However, to realize meaningful conclusions, these studies rely on accurate measurements of individual traits and population characteristics. Here, we evaluate the accuracy of the observational methods used to measure reproductive traits in individually marked black-tailed godwits (Limosa limosa limosa). By comparin
My research centres on a topic that will be familiar to many of you – namely the proliferation of paperwork and documentation demands that characterises work in many contemporary organisations. More specifically, I take as my point of departure a crux from the Swedish education sector, namely that there is a broad will – from actors at all levels of the schooling system – politicians, the Swedish
The PResymptomatic EValuation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) is an investigator-driven study that was created in 2011 and enrolled cognitively normal older adults with a family history of sporadic AD. Participants are deeply phenotyped and have now been followed annually for more than 12 years (median follow-up 8.0 years, SD 3.1). Multimodal magnetic reson
Galactic cosmic rays (GCRs) interact with the Earth’s atmosphere to produce energetic neutrons and cosmogenic radionuclides, such as 14C. The atmosphere is partially shielded from the interstellar GCR spectrum by both the geomagnetic and solar magnetic fields. Solar shielding is often expressed as the heliospheric modulation potential ϕ, which consolidates information about the strength and struct
The tunneling dynamics of a magnetic Dy164 quantum gas in an elongated or pancake skewed double-well trap is investigated with a time-dependent extended Gross-Pitaevskii approach. Upon lifting the energy offset, different tunneling regimes can be identified. In the elongated trap and for sufficiently large offset, the different configurations exhibit collective macroscopic tunneling. For smaller o
Numerous studies have demonstrated the significant impact of the resolution of solar irradiation data on the outcomes of hourly production models. Accurate integration of photovoltaic (PV) systems sometimes demands a high-resolution global horizontal irradiance (GHI) time series to capture the rapid fluctuations in PV power output induced by swift irradiance changes. Most of the available database
Significant groundwater (GW) head decline due to excessive withdrawal is an essential hydrological concern in several major plains of Iran. The capacity of an aquifer to retain GW can be described through the storativity parameters. Traditional methods to define these parameters are costly, time-consuming, and sometimes ineffective. The storativity of an aquifer, irrespective of its confinement ty
Background: Access to contraception can be a transformational intervention towards advancement of education, health, and freedom of choice. Countries have committed to improving access to contraception enshrined in the sustainable development goals (SDGs), indicator 3.7.1. Our study seeks to investigate the level of inequality in current use of modern contraception and unmet need for contraception
Background: The drive for home care has increasingly impacted the organization and allocation of resources within the Swedish healthcare system. Objectives: With an interest in uncovering prerequisites for palliative care, this study aimed to investigate longitudinal trends in place of death within the adult Swedish population from 2013 to 2019 and examine potential associations between place of d
Crime fiction at the service of society – on some perils in the making of a Scandinavian film town During the last decades, regional film funds and tax breaks have altered the geography of European film production. Film and other forms of audiovisual media are increasingly produced in places far from where such activities customarily occurred. Sweden may be among the countries where the tendency
With a broad approach it is possible to see the importance of the many parts in the whole, and to grasp the cultural situations that surround reading in combination with travel. Interaction and co-production are of great importance. Fiction influences reality, which in turn influences the fiction, which in turn… and so on. Fiction can function as an optical lens for reality. The difference between
inget herrgårdsliv Vilka satsningar lyfter forskningen? All inclusive exkluderar värdlandet 2 LUM nr 4 | 2012 LUM nr 4 | 2012 3 Inför en trollbunden publik spelade International Theatre of Malmö lunchteater på Pufendorfinstitutet. Konstnärlig ledare för ensemblen är Etzel Cardeña, Lunds psykologi professor med särskild inriktning mot hypnos och parapsykologi. När Etzel Cardeña läste psykologi på
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-4-2012.pdf - 2026-07-22
