Filtyp
The aim of this study was to investigate the association between smoking and bone mineral density (BMD) and radiographically verified prevalent vertebral fractures and incident fractures in elderly men. At baseline 3003 men aged 69 to 80 years of age from the Swedish Mr Os Study completed a standard questionnaire concerning smoking habits and had BMD of the hip and spine measured using dual-energy
The increasing number of new psychoactive substances made available for recreational drug use has created a challenge for clinical toxicology and drug testing laboratories. As a consequence, the routine immunoassay drug testing may become less effective due to an increased occurrence of false negative and false positive screening results. This work aimed to extend the knowledge about analytical cr
Seed bank is a plant life history strategy against the unpredictability of the biotic and the abiotic environment. We simulated competition between a seed banking and a non-banking morph of an annual plant. A constant fraction of the banker morph seeds was allocated to the seed bank, where they had a constant mortality and germination rate. All surviving seeds of the non-banker morph germinated in
Wilms tumor (WT) is characterized by a nonrandom pattern of chromosome aberrations, but the clinical significance of different cytogenetic patterns is unknown. The present study describes the cytogenetic findings and the clinical course in a cohort of 39 children with WT. Samples for short-term culturing and cytogenetic analysis were obtained during a 15-year period. Clonal chromosome aberrations
Objective: To determine the nature and extent of undersupply and the economic consequences of oversupply of medication among non-adherent patients. Methods: This study used copies of repeat prescriptions (=multiple dispensations), collected during 1 week in 2002 at 16 Swedish community pharmacies. For patients with a refill adherence below 80%, treatment gaps were defined as the number of days the
The Multi-plume Aerosol dynamics and Transport (MAT) model has been developed to study the dynamics of the particle size distribution in urban environments. The MAT model uses a novel multi-plume scheme for vertical dispersion and routines of the aerodynamics models AERO3. It treats the processes: emission from a near ground source, dilution with background air, deposition, coagulation and condens
During the prolonged course of chronic viral infection there is a continuous reciprocal interaction between the host immune defence system and the viral immunogens, and viral genetic mutations capable of circumventing host immune defence could be selected for. Our observation of increasing prevalence of heterogeneity in the DNA sequence coding for the ‘a1 determinant of HBsAg in patients with pres
Background: The aim of this study is to estimate ovarian volume, number and volume of antral follicles, and ovarian power Doppler vascular indices as assessed by three-dimensional (3D) transvaginal grayscale and power Doppler ultrasound in women using combined oral contraceptives (COC). Study Design: Two hundred thirteen gynecologically asymptomatic women 20-39 years old using COC were examined wi
A total of 3,016 malignant solid tumors (kidney, colorectal, breast, head and neck, ovarian, and lung carcinomas, neuroglial tumors, malignant melanoma, and testicular germ cell tumors) were selected for statistical analyses regarding karyotypic evolution. Genomic imbalances, i.e., net gains and losses, present in more than 5% of each tumor type were identified. Individual tumors were then classif
The global surgery workforce is in crisis in many low- and middle-income countries (LMICs). The shortage of surgery, obstetrics, and anesthesia providers is an important cause of the unmet need for surgical care in LMICs. The goal of this paper is to summarize the available literature about surgical physicians in LMICs and to describe ongoing initiatives to supplement the existing surgical workfor
This thesis deals with the empirical testing of trade theories, traditionally used to analyze international trade, using regional data on production and trade. This thesis consists of three main essays. In the first essay, we analyze Swedish regional production. In the first part, we focus on the effects of comparative advantage in predicting regional manufacturing production. In so doing, we use
Popular Abstract in Swedish Mängden och kvaliten på avfall förändras när intresset för resurserna i avfallet ökar. Ett omhändertagande av avfall med sortering, återvinning, förbehandling och utnutjande av energi producerar nytt avfall. En del hamnar på deponin. En möjlig följd är att det organiska materialet som deponeras minskar. En annan är att avfallet blir torrare. Framförallt inom EU finns deWhen attention is drawn to the recovery of resources within waste, the amount and types of waste disposed of at landfills change. A waste management system based on separate kerbside collection, sorting, recycling, and pretreatment with material and/or energy recovery produces new residues, which finally end up at landfills. This is the case in, for example, the US and the EU. As a possible result
In this thesis we present new worst case computational bounds on algorithms for some of the most well-known NP-complete and #P-complete problems and their optimization variants. We consider graph problems like Longest Path, Maximum Cut, Number of Perfect Matchings, Chromatic and Domatic Number, as well as Maximum k-Satisfiability and Set Cover. Our results include I a) There is a polynomial--
Objective: In this study, our aim was to investigate how different immunohistochemical techniques may influence the result of BCL6 positivity and categorization in germinal center (GC) and non-GC derived diffuse large B-cell lymphoma (DLBCL), as it has been proposed that classification of DLBCL according to cell-of-origin by immunohistochemistry may be performed as a routine procedure in the diagn
cAMP signaling is important for the regulation of insulin secretion in pancreatic beta-cells. The level of intracellular cAMP is controlled through its production by adenylyl cyclases and its breakdown by cyclic nucleotide phosphodiesterases (PDEs). We have previously shown that PDE3B is involved in the regulation of nutrient-stimulated insulin secretion. Here, aiming at getting deeper functional
One of the conspicuously recurrent motifs in Christina Stead's novels is the quest. The present study centres on For Love Alone, the novel in which the prominence of this motif culminates in the depiction of Teresa Hawkins' successful quest, which contains both social and spiritual elements. The novel has a discernible romance structure, and a number of heroic models, including both male and femal
Surfaces subjected to rolling and sliding contacts may suffer from contact fatigue. The cam and roller follower mechanism is a typical rolling and sliding contact. This thesis deals with the running in aspects to avoid high stress variation that leads to fatigue wear and the aspect of what happens to indentation damages that occurs on the surface if there are any particles in the lubricant. The pa
