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Background: Sleep and behavioral regulation are both vital for early healthy development. Yet, little is known about the relative contribution of genetic and environmental factors to early sleep and regulatory behaviors, or how these etiological influences may change during the first months of life. Methods: Genetic and environmental influences on sleep, settle, and crying behaviors at 2 and 5 mon
In international trade with buyer and seller in different countries the parties can be insecure whether their counterpart will fulfil its contractual obligations in accordance with the contract of sale. The seller can be insecure in getting paid for his goods at contractual time and the buyer's insecurity can be whether the goods will be shipped at the contractual time and in contractual state
Wall-bounded turbulence is relevant for many engineering and natural science applications, yet there are still aspects of its underlying physics that are not fully understood, particularly at high Reynolds numbers. In this study, we investigate fully developed turbulent pipe flows at moderate-to-high friction velocity Reynolds numbers ( 361 ≤ R e τ ≤ 2000 ), corresponding to bulk velocity-based Re
Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal disease. The only option for curative treatment is resection of the tumor followed by standard adjuvant chemotherapy. Yet, early relapse due to chemoresistance is almost inevitable. Herein, we delineated the genetic intratumor heterogeneity in resected PDAC, with the aim to identify evolutionary patterns that may be associated with ov
Introduction: Surface Guided Radiation Therapy (SGRT) is being increasingly implemented into clinical practiceacross a number of techniques and irradiation-sites. This technology, which is provided by different vendors, canbe used with most simulation- and delivery-systems. However, limited guidelines and the complexity of clinicalsettings have led to diverse patterns of operation. With the aim to
Background: Patients presenting with synchronous colorectal liver metastases are increasinglybeing considered for a curative treatment, and the liver-first approach is gaining popularity in thiscontext. However, little is known about the completion rates of the liver-first approach and itseffects on survival.Methods:A systematic review and meta-analysis of liver-first strategy for colorectal liver
Migration distance and seasonal redistribution patterns may vary between and within bird populations. A common pattern is leap-frog migration, in which northerly breeding populations migrate farther and winter south of more southerly breeding populations. Another common pattern is difference in migration distances between males and females within the same population. Evidently different population
The paper bridges sustainability and market-shaping literature to conceptualize and empirically explore the role of social innovation in the implementation of a proactive corporate sustainability by a MNE in the emerging market. An in-depth qualitative study of H&M’s fair living wages program in Bangladesh reveals a number of grand challenges and proactive activities on two levels: factory and
A new species, Begonia pasighatensis D.Borah, Taram & Wahlsteen (Begoniaceae) is described and illustrated. It is easily distinguished from all other species in the section Platycentrum by its swollen, spherical ovary with two wings reduced to ridges and a long, pointing upper wing. The new species belongs to Begonia section Platycentrum and is distributed in southern Arunachal Pradesh in East
Rubus "firmus" is a very rare plant in Norway; it is only known from a 500 m long coastal strip nearthe sea- shore in Grimstad, Aust-Agder fylke. The identity of the name R. firmus is obscure, and it is not known whether the original plant is a species or a hybrid; we do not accept this name as correct for the Norwegian plant. The Norwegian plants are not very homogeneous and have the chromosome n
Climate change is advancing the onset of phenological events, with the rate of advance varying among species and trophic levels. In addition, local populations of the same species may show genetic differences in their response to seasonal cues. If populations of interacting species differ in their response, then climate change may result in geographically varying shifts in the community-level dist
Rationale and Objectives. The poor specificity of galactography, the imaging modality generally indicated in cases of nipple discharge, has led to a large number of biopsies with negative results. A quantitative scheme for classifying galactographic findings might help reduce the number of such biopsies in the future. As a first step toward that goal, the authors have studied one quantitative meth
High hyperdiploid acute lymphoblastic leukemia (ALL) is one of the most common malignancies in children. The main driver event of this disease is a nonrandom aneuploidy consisting of gains of whole chromosomes but without overt evidence of chromosomal instability (CIN). Here, we investigated the frequency and severity of defective sister chromatid cohesion—a phenomenon related to CIN—in primary pe
This book gives a critical account of various methods used in music analysis. In the first chapter, a number of current approaches such as semiotics, musical implications, Schenkerian analysis, and generative theory are demonstrated on Mozart’s K. 331 theme. Five essays deal with important concepts in music analysis: ambiguity, formal proportions, and similarity within and between works. A further
BACKGROUND: Laparoscopic surgery remains limited in low-resource settings. We aimed to examine its use in Mexico and determine associated factors.METHODS: By querying open-source databases, we conducted a nationwide retrospective analysis of three common surgical procedures (i.e., cholecystectomies, appendectomies, and inguinal hernia repairs) performed in Mexican public hospitals in 2021. Procedu
Purpose: The number of persons who have successfully completed treatment for a cancer diagnosed during childhood and who have entered adulthood is increasing over time, and former patients will become aging citizens. Methods: Ten years ago, an expert panel met in Erice, Italy, to produce a set of principles concerning the cure and care of survivors of childhood and adolescent cancer. The result wa
