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This masters thesis deals with mathematical signal detection in the field of NQR,Nuclear Quadrapole Resonance, which is a non-invasive spectroscopic technique usedto identify specific substances. The thesis has two main focuses, where the first isto propose novel methods for parameter estimation, especially for identification ofunknown signals. These extend the existing Capon and APES methods for

Early life air pollution exposure may play a role in development of respiratory infections, but underlying mechanisms are still not understood. We utilized data from two independent prospective birth cohorts to investigate the influence of prenatal and postnatal ambient air pollution exposure of PM2.5, PM10 and NO2 on maternal and child proteomic profiles and the risk of daily diary-registered com

The Carina Nebula is an active star-forming region with several open clusters rich in massive OB stars, thus making it an optimal target for studying stellar properties such as rotation for large samples of these early-type stars. We studied a sample of early-type stars probable members of the eight open clusters in the Carina Complex. The observational data consist of high-resolution spectra from

(Formula presented) boson events at the Large Hadron Collider can be selected with high purity and are sensitive to a diverse range of QCD phenomena. As a result, these events are often used to probe the nature of the strong force, improve Monte Carlo event generators, and search for deviations from standard model predictions. All previous measurements of (Formula presented) boson production chara

Given the increasing number of heterogeneous data stored in relational databases, file systems or cloud environment, it needs to be easily accessed and semantically connected for further data analytic. The potential of data federation is largely untapped, this paper presents an interactive data federation system (https://vimeo.com/319473546) by applying large-scale techniques including heterogeneo

Despite a wealth of sophisticated CFD-methods, most designs are still based on one-dimensional and two-dimensional inviscid analytical tools. In such methods, realistic loss and angle assessment are indeed critical in order to arrive at correct loading, flow coefficient and reaction. The selected values are normally retained through the detailed design sequence for each iteration. This means that

High hyperdiploid acute lymphoblastic leukemia (HeH ALL), one of the most common childhood malignancies, is driven by nonrandom aneuploidy (abnormal chromosome numbers) mainly comprising chromosomal gains. In this study, we investigate how aneuploidy in HeH ALL arises. Single cell whole genome sequencing of 2847 cells from nine primary cases and one normal bone marrow reveals that HeH ALL generall

Objective: To evaluate sick leave after meniscal repair vs arthroscopic partial meniscectomy (APM) and, for comparison, vs the general population. Method: Using Swedish register data we included all employed persons aged 19–49 years in the general population of Skåne region and identified those having had meniscus repair or APM in the period of 2005–2012. We retrieved data on sick leave during 1 y

Background: Weight gain and hypertension are well known adverse effects of treatment with high-dose glucocorticoids. Objective: To evaluate the effects of 2 years of low-dose glucocorticoid treatment in rheumatoid arthritis (RA). Design: Pooled analysis of 5 randomized controlled trials with 2-year interventions allowing concomitant treatment with disease-modifying antirheumatic drugs. Setting: 12

In order to meet the wishes of Lund University management to showcase and display the work conducted in relation to the UN Sustainable Development Goals, the management of Lund's Pure installation has undertaken a project. The direct use of automatic tagging of SDGs turned out to be insufficient, so we devised a number of steps to utilize the data in a controlled manner. This includes a general me

Acral melanoma is a clinical subtype of melanoma with high mortality, on which research is limited in scope. This study aimed to assess incidence trends and melanoma-specific survival rates for acral melanoma in the Swedish population from 1990 to 2020.This cross-sectional study included patients with an acral melanoma diagnosis from 1990 to 2020 from the nationwide, population-based Swedish Melan

Purpose: To investigate long-term trends and changes in the pattern of use of lamotrigine (LTG). Methods: Retrospective survey of a large, routine therapeutic drug monitoring database. Results: Twelve thousand one hundred and seven samples from 4123 subjects were analysed from October 1999 to May 2007. Within this period, the mean daily dose rose from 183 to 253 mg, whereas the median dose remaine

Hotspot tracks (quasilinear chains of seamounts, ridges, and other volcanic structures) provide important records of plate motions, as well as mantle geodynamics, magma flux, and mantle source compositions. The Tristan-Gough-Walvis Ridge (TGW) hotspot track, extending from the active volcanic islands of Tristan da Cunha and Gough through a province of guyots and then along Walvis Ridge to the Eten

We present a detector that, by thresholding the output of the matched filter, gives MLSD-decisions on binary, antipodally modulated symbols that have been corrupted by intersymbol interference and additive Gaussian noise. The detector is simple in structure, consisting of a whitened matched filter and two variable thresholds for each symbol to be detected. The detector will make decisions on some,