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3D biomaterial models of human brain disease Neurochemistry International 147 (2021) 105043 Available online 20 April 2021 0197-0186/© 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). 3D biomaterial models of human brain disease Janko Kajtez a,*, Fredrik Nilsson a, Alessandro Fiorenzano a, Malin Par
Background: Sleep disturbances are common among older people (>65 years). Further, long-term use of sedative-hypnotics in older people is associated with morbidity and mortality. However, older people represent a large span of life years, and few studies have included the oldest-old above 85 years. Aim: To investigate and compare sleep quality, use of hypnotics and sleeping habits in different age
Environmental conditions, dispersal lags, and interactions among species are major factors structuring communities through time and across space. Ecologists have emphasized the importance of biotic interactions in determining local patterns of species association. In contrast, abiotic limits, dispersal limitation, and historical factors have commonly been invoked to explain community structure pat
The analysis of annual extremes of hydrological and meteorological variables is frequently complicated by the presence of gaps in record, and when records are not only fragmented but also short, it is necessary to utilize to the full the information contained in them. One method is to abstract for statistical analysis all extreme events whose peaks exceed a pre-selected threshold value, but the th
Context and Objective: Intraportal islet transplantation can restore insulin production in type 1 diabetes patients, but its effect is subject to several interfering processes. To assess the influence of beta-cell loss before and during engraftment, we searched for a real-time marker of beta-cell destruction. Previous studies showed that 65-kDa isoform of glutamate decarboxylase (GAD65) is dischar
Background: Myeloid cells have been associated with physiological and pathological angiogenesis, but their exact functions in these processes remain poorly defined. Monocyte-derived tissue macrophages of the CNS, or microglial cells, invade the mammalian retina before it becomes vascularized. Recent studies correlate the presence of microglia in the developing CNS with vascular network formation,
ARTICLE The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study Jeffrey P. Krischer & Kristian F. Lynch & Desmond A. Schatz & Jorma Ilonen & Åke Lernmark & William A. Hagopian & Marian J. Rewers & Jin-Xiong She & Olli G. Simell & Jorma Toppari & Anette-G. Ziegler & Beena Akolkar & Ezio Bonifacio & the TEDDY Study Group Received: 4 September 2014
https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_43_krischer_diabetologia_2015.pdf - 2026-07-18
Ultrashort, coherent light pulses in the extreme ultraviolet (XUV) wavelength region are excellent tools for a wide range of experiments. These XUV pulses are in particular used to characterize electron dynamics. Additionally, the high photon energy enables quantum control of short-lived transitions in atoms. These transitions are of interest for ultrafast quantum control as the bandwidth of the c
The Greenhouse Gas Reduction Mandate (GGRM, reduktionsplikten) is Swedish legislation focused on reducing carbon emissions by mandating that the emissions of certain fuels are reduced by a specified percentage, that percentage increasing each year. This paper investigates the rationale behind a political drive to decrease the GGRM, the cost-effectiveness of the GGRM, and the consequences of t
Mediterranean regions have a growing number of extreme weather events due to rapid change of climate. Cork oak, which is located in the western Mediterranean area, has become a very valuable resource within the western Mediterranean forests. Therefore, assessment of the impacts of climate extremes upon cork oak can help us produce better forest management practices for coping with future climate c
Ett av de svåraste momenten för en domare är hur de ska värdera en muntlig utsaga. Vid sexualbrott är det vanligt förekommande att en utsaga är den största bevisningen, det är därför av största vikt att en utsaga värderas på ett objektivt och godtagbart sätt. I Sverige finns det ingen lagreglering om hur en bevisvärdering ska gå till. För att rättssäkerheten inte helt ska försvinna finns det riktlOne of the most difficult moments of a judge is how to evaluate an oral statement. When dealing with sex crimes the oral statement is usually the biggest evidence, it is therefore important that an oral statement is valued in an objective and acceptable manner. In Sweden, there is no legal regulation on how an evaluation on oral statements should work. There are guidelines for the evaluation of or
The aim of this paper is to investigate the exposure of Fair Trade (FT) importers in Germany, operating based on the principles of the World Fair Trade Organization (WFTO), to foreign exchange (FX) rate risk in the light of the current depreciation of the Euro. The ongoing high volatility of the Euro exchange rate strongly affects Fair Trade companies that import products mostly from developing co
With population that exceeds 90 million inhabitants, Egypt is one of the large Arab developing countries where the government policies headed towards constructing new urban communities to absorb the vast increase in population. Although the physical planning of the new urban settlements took into consideration the existence of outdoor recreational services and facilities, the quality and adequacy
In the 'on-the-go' society of today, the use of single unit beverage packages has increased. Consequently, the interaction between the consumer and the package have also attracted greater interest when trying to gain advantages in a competitive market. One way of gaining such an advantage is by decreasing the developing costs of products: either by reducing time spent, or money invested in
Viruses that infect single-celled algae strongly regulate microalgae growth and community composition through cell lysis, enable nutrient recycling in marine ecosystems, and offer valuable insights into early stages of viral evolution. One major group, the Bacilladnaviridae family of single-stranded DNA viruses, infects diatoms in marine environments. Here, we present the capsid structure of Ch
A method that could assess the whole vehicle non-exhaust particle (NEP) emission from the whole vehicle level was proposed by combining sealed housing with the chassis dynamometer. The intake and exhaust systems were connected to the out of the chamber to avoid possible effects on NEP emissions. The most distinguishing feature of the proposed method is the whole vehicle assessment of the NEP. Base
Weather conditions affect animals in many different ways. Variation in temperature, rainfall, wind, and other environmental variables can have an impact at a range of temporal and spatial scales and at every level from individual behavior to species distributions. The interactions between these variables may be particularly important but are often overlooked. Hence, understanding how animals respo
Interest in the culture of freshwater crayfish throughout Europe has increased during the last few decades. However, the effects of both introduced and native crayfish species on the structure and diversity of freshwater communities has received little attention. In this paper, I review the impact of crayfish on macrophytes, algae, invertebrates, amphibians and fish; also I compare the impact of i
INTRODUCTION: Depression is common, increasing among adolescents and carries risk of disability, lower educational achievements, cardiovascular disease, substance abuse, self-harm and suicide. The effects of evidence-based treatments with medication or psychotherapy are modest. Aerobic exercise is a promising intervention for adolescents with depression, but available studies are hampered by metho
Båtklubben i Kiviks hamn har länge upplevt problem med stora vågor i hamnbassängen. Denna studie ämnar att fastslå vilka vågförhållanden och fenomen som ger upphov till dessa problem, samt att föreslå åtgärder. En undersökning av vågklimatet utanför hamnen utförs med hjälp av en enkel modell, kallad SPM, som beräknar en tidsserie vågor utifrån meteorologisk och geografisk data. För att kartlägga vThe yacht club in Kivik marina has experienced problems with large waves in the harbour basin for a long time. This study aims to determine the wave conditions and phenomena that give rise to these problems, and to propose measures. An investigation of the wave climate outside the harbour is carried out using a simple model, called SPM, which calculates a time series of waves based on meteorologic
