Sökresultat

Support to the Strengthening of the African Regional Human Rights Mechanisms   - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advi

https://rwi.lu.se/support-to-the-strengthening-of-the-african-regional-human-rights-mechanisms/ - 2026-06-22

Background: Pathologist-read tumor-infiltrating lymphocytes (TILs) have showcased their predictive and prognostic potential for early and metastatic triple-negative breast cancer (TNBC) but it is still subject to variability. Artificial intelligence (AI) is a promising approach toward eliminating variability and objectively automating TILs assessment. However, demonstrating robust analytical and p

Introduction: Self-monitoring of blood glucose (SMBG) is the standard of care for women with gestational diabetes mellitus (GDM). This study aimed to review SMBG profiles in women with GDM and to examine how glucose metrics derived from SMBG relate to fetal overgrowth and infants born large for gestational age (LGA, >90th percentile). Material and Methods: This was a single-center, historical, obs

The accumulation of tau abnormality in sporadic Alzheimer’s disease is believed typically to follow neuropathologically defined Braak staging. Recent in-vivo PET evidence challenges this belief, however, as accumulation patterns for tau appear heterogeneous among individuals with varying clinical expressions of Alzheimer’s disease. We, therefore, sought a better understanding of the spatial distri

RNA therapeutics is a new class of targeted therapies that has entered the clinic in the last decade. Lipid nanoparticles (LNPs) and conjugation to N-acetylgalactosamine have proven to be efficient strategies to deliver RNA payload to the liver. Successful delivery of sensitive RNA molecules to other target tissues or tumors remains one of the key challenges with the development of new RNA-based t

Background: Totally implantable venous access devices (TIVADs) have improved the quality of life for seriously ill and cancer patients. These devices represent a convenient option when long-term venous access is indicated. The Subclavian and Internal Jugular Veins are the vessels of choice for catheterization [1]. However, if it is not possible to catheterize them, an alternative vein should be so

Background: Prognostication of neurological outcome in patients who remain comatose after cardiac arrest resuscitation is complex. Clinical variables, as well as biomarkers of brain injury, cardiac injury, and systemic inflammation, all yield some prognostic value. We hypothesised that cumulative information obtained during the first three days of intensive care could produce a reliable model for

Background: Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson’s disease (PD). Opicapone (OPC) is a third-generation, once-daily catechol-O-methyltransferase inhibitor shown to be generally well tolerated and efficacious in reducing OFF-time in two pivotal trials in patients with PD and end-of-dose motor fluctuations. The OpiCapone Effect on motor fluctuations

Anaerobic digestion (AD) offers considerable potential in the production of energy from renewable sources, and is being increasingly recognised as a sustainable technology for the treatment of waste. The production of energy from waste such as municipal solid waste (MSW), lipid-rich waste, and agricultural biomass and waste may play an important role in the production of renewable energy given the

Today an increasingly large and diverse audience spends more and more time and money on computer games; the actual player can now be anyone. Gameplay, whether it is raiding online in World of Warcraft, an evening of Guitar Hero in the living room with friends, or a quick round of Sudoku Master on the Nintendo DS while commuting home from work, has become part of the everyday life of millions of pe

Background: An increased knowledge of predictors that might affect survival in Alzheimer’s disease (AD) patients treated with cholinesterase inhibitors (ChEIs) is important for clinicians and for the health services. Impairment in activities of daily living (ADL), somatic diseases, and psychiatric symptoms may influence mortality in AD. We aimed to study the impact of functional capacity and conco

BakgrundVaccination är en av de viktigaste folkhälsoinsatserna för att rädda liv och hindra spridning av smittsamma sjukdomar. Tack vare vaccinationer har miljontals liv räddats världen över. Men det räcker inte att säkra och effektiva vaccin tas fram och tillgängliggörs. En förutsättning för framgångarna är att individer accepterar att bli vaccinerade. Under senare tid har forskningsområdet om vaThe vaccination coverage in Sweden's National Immunization Program (NIP) has been highand stable for decades. Although the coverage is high, few studies have assessed parental vaccineacceptance in Sweden. This doctoral thesis aimed to provide an in-depth understanding of currentparental vaccine acceptance, focusing particularly on Human papillomavirus (HPV) and measles, mumps and rubella (MMR) vac

Drug side effects (DSEs) or adverse drug reactions (ADRs) are a major concern in the healthcare industry, accounting for a significant number of annual deaths in Europe alone. Identifying and predicting DSEs early in the drug development process is crucial to mitigate their impact on public health and reduce the time and costs associated with drug development. Objective: In this study, our primary

The broad goal of this thesis is to develop a deeper mathematical understanding of the processes at work in the neuronal network of a brain by rigorously examining very fundamental elements of the processes involved. Paper I considers the flow of discrete signals on a graph and Paper II the complexity arising from the interplay of simple units. The concrete probabilistic investigations of such mod

Background: The introduction of highly active antiretroviral therapy has significantly improved the life expectancies of children and adolescents living with HIV, leading to an increased number transitioning to adult care. However, there has been a lack of studies in Ethiopia focusing on factors influencing the success of this transition. Therefore, this study aimed to determine predictors of a su

IMPORTANCE: The introduction of solid or semisolid foods alongside breast milk plays a vital role in meeting nutritional requirements during early childhood, which is crucial for child growth and development. Understanding the prevalence of zero-food children (defined for research purposes as children aged 6 to 23 months who did not consume animal milk, formula, or solid or semisolid food during t

The European solar energy business faces the challenge of developing more cost-effective solar energy systems and one solution could be using concentrating hybrid PVT systems. Two such hybrids, the Swedish systems MaReCo and Solar8, are evaluated in this study. MaReCo is a fixed concentrating system with a high angle of acceptance. Solar8 is a new system, which is under development. It is inspired

Mineralogical and geochemical studies of the non-marine Permian–Triassic (P–Tr) boundary across two stratigraphically wellconstrained sections (Commando Drift Dam and Wapadsberg, Eastern Cape Province) in the southern Karoo Basin, South Africa, have been undertaken to provide further input on the cause of this mass extinction event, and so has a sedimentological and geochemical evaluation of a thi

In this thesis, a high-repetition-rate attosecond light source based on high-order harmonic generation in gases was used to perform time-resolved electron spectroscopy in atoms and solids. The source was driven by few-cycle near-infrared laser pulses with a controllable carrier-to-envelope phase, enabling the generation of sequences of two to four attosecond pulses in the extreme ultraviolet range

I samband med lantmäteriförrättningar där ersättningsbeloppet behöver framtas med hjälp av de värderingsmedel som Lantmäteriet eller utsedd värderingsman har att tillgå är det ytterst viktigt att ingångsparametrarna är korrekta. Då fastighetsregleringar där vinstfördelning blir aktuellt och där genomsnittsvärdeprincipen aktualiseras är det råtomtmarksvärdet som eftersöks. I värderingsutlåtandet reDuring land surveying operations, the amount of compensation needs to be calculated using the valuation means taken by the land surveyor or appointed appraiser. For this reason, it is important that input parameters are correct. As profit distribution is a pressing concern in relation to real estate regulations, raw land value is sought after. In this case, the responsible land surveyor reports fo