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Background Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion has not been well studied. Methods We randomly assigned, in a 1:1 ratio, patients who had taken factor Xa inhibitors within 15 hours before having an a
Group A Streptococcus (GAS) is a significant human pathogen that has developed multipleimmune evasion mechanisms to counter the host immune response. One of these mechanisms involvesthe production of the M protein, which, amongst other things, acts as an anti-phagocytic factor and canbind host proteins. Another is the ability of M protein to bind a human protein called fibronectin (Fn). Thisprotei
Precipitation is a major component of the water cycle. Accurate and reliable estimation of precipitation is essential for various applications. Generally, there are three main types of precipitation products: satellite based, reanalysis, and ground measurements from rain gauge stations. Each type has its advantages and disadvantages. Recent efforts have been made to develop various merging methods
In March of 2017, artist, field recordist, soundwalk leader and artistic researcher Jacek Smolicki invited me to the Detroit Gallery to join him and artist/illustrator Jenny Soep in a project employing different modes of transposition. Smolicki and Soep wanted to explore how materials transformed when transposed through different mediums. First, Jacek Smolicki collected 31 short field recordings.
The plant plasma membrane H+-ATPase is a predominant membrane enzyme that provides the energy for secondary active transport across the plasma membrane. Consequently, the H+-ATPase is thought to play a major role in many cell processes, and it is implicated to be regulated by a number of factors, including hormones, blue light, and fungal toxins The plant plasma membrane H
Popular Abstract in Swedish Biovätgas är en mycket energirik och förnyelsebar energikälla för bilar och elproduktion som genererar mycket lite av växthusgasen koldioxid. Vätgasen kan framställas av billiga råvaror såsom hushållsavfall, industriellt avfall och av lignocellulosa. Lignocellulossa är en komplex polymer som finns bland annat i olika träslag och gräs. Detta leder till att råvaropriset mA high substrate conversion efficiency is a prerequisite for an economically feasible biohydrogen production. Caldicellulosiruptor saccharolyticus is a strictly anaerobic extreme thermophilic bacterium that is able to convert the theoretical maximum of 4 mol/mol glucose to H2. It can grow and produce H2 on a broad spectrum of sugars ranging from monomers (hexoses and pentoses) to more complex suga
Signs of Flesh: Institution and Body in Accounts of Paranoia (Notes on Schreber and Fabian) As the call for paper to this conference aptly states, phenomenology holds that "[c]onsciousness [is] dependent on a body and a world, which bestow it with existence and meaning." My take on this phenomenologist axiom would be to suggest a complementary thesis, something like: "The world (understood as the
Semantic segmentation is a fundamental problem in visual perception with a wide range of applications ranging from robotics to autonomous vehicles, and recent approaches based on deep learning have achieved excellent performance. However, to train such systems there is in general a need for very large datasets of annotated images. In this thesis we investigate and propose methods and setups for wh
Therapy is the often-used treatment for cancer patients, even those that undergo resection surgery. While milestones have been surpassed throughout the decades for a number of cancer types, there are those that comprise of characteristics limiting effectiveness of treatments. For these, such as some breast and pancreatic cancers, other pursuits must be explored to identify avenues for beneficial t
Importance: Better understanding of patients' attitudes toward deprescribing specific medications will inform future deprescribing interventions. Objective: To investigate older adults' attitudes toward deprescribing by investigating which medications they would like to have deprescribed, the reasons why, and patient factors associated with interest in deprescribing. Design, Setting, and Participa
Objective Exposure to hexavalent chromium (Cr(VI)) occurs during several occupational activities and leads to lung cancer. Growing evidence suggests that microRNA (miRNA) plays an important part in carcinogenesis. This study was to explore circulating miRNAs of Cr(VI) exposed workers and to identify the potential biological function of differentially expressed miRNA (DEM).Material and Methods This
We assessed hepatocellular carcinoma (HCC) risk associated with smoking and alcohol consumption and their interactions, using both questionnaire data and objective serum biomarkers. Information on smoking and alcohol consumption was collected at baseline from 450,112 participants of the EPIC cohort, among whom 255 developed HCC after a median follow-up of 14 years. In a nested case–control subset
This paper presents findings from a longitudinal, experimental project investigating the effect of translation on the morphosyntactic accuracy of advanced Swedish (L1) learners of English (L2). The subjects were first-year students of English at a Swedish university. The curriculum was communicative and translation (Focus-on-Forms) was used judiciously. The research is couched in cognitive psycho
Popular Abstract in Swedish Avhandlingen utgörs av en detaljerad studie av ett enskilt antikt byggnadsverk – Caecilia Metellas mausoleum. Detta gravmonument tillhörde en högättad romersk kvinna och är beläget intill Via Appia strax utanför Rom. Byggnaden utmärker sig bland annat genom sin storlek, men också genom sin högst ovanliga arkitektoniska utformning. Syftet med studien är att söka förstå dThe present thesis constitutes a close study of a single architectural monument, the tomb of Caecilia Metella. This is a well-preserved cylindrical tomb situated on the Via Appia outside Rome, and it is generally associated with sepulchral buildings of the traditional tumulus type. An inscription reveals that the occupant of the grave was a noble woman belonging to one of the most prestigious fami
Visioner och framtidsbilder efterfrågas ofta för att motivera och inspirera till samhälleliga förändringar. Sådana visioner kan bygga på politisk förändring eller måla upp bilder av teknisk utveckling som hjälper oss att lösa svåra samhälleliga problem. Den typen av visioner är kanske speciellt viktiga när vi strävar efter en hållbar utveckling, och framför allt ifall vi vill motverka att jordens Different kinds of representations of the future are often asked for in order to motivate and inspire societal change. These envisioned futures can be based on political or behavioural change, or may visualize technical developmentwhich could help us solve complex societal problems. The latter type of epresentation is especially important if we aim for sustainable development, and even more so if
Collimated sprays of paticle, known as jets,are abundantly produced in high-energy proton-proton (pp) collisions, and are predicted by many theories of physics beyond the Standard Model. This thesis reports first on the calibration of jets with focus on the data-driven in situ calibration. Two searches for new physics phenomena in events with jets in the final state are then presented. The analyse
Personer som självskadar har historiskt sett inte haft så mycket att säga till om i sina egna vårdprocesser. När de har sökt psykiatrisk vård akut, ofta för att de upplevt akut svåra tankar och impulser att skada sig själva och kanske har planerat göra suicidförsök, har personer som självskadar ofta blivit hemskickade utan hjälp, eller så har de blivit inlagda för långvarig psykiatrisk vård som faPeople who self-harm have historically not had much say in their healthcare processes. When seeking psychiatric emergency care, people who self-harm have frequently been turned away, or admitted for lengthy hospitalisations that may aggravate self-harm. The attitudes of psychiatric clinicians toward people who self-harm are important to healthcare users’ experience of care, affecting quality and a
The textile industry generates vast wastewater containing synthetic dyes and polymeric additives like poly(vinyl alcohol) (PVA), which pose serious environmental challenges. Conventional treatment methods struggle to remove these contaminants while enabling resource recovery. PVA, widely used as a textile sizing agent, increases treatment complexity, while reactive dyes like Reactive Yellow 145 ar
Rwanda is endeavouring to deal with its evil past of internal war and genocide to enable a peaceful future. Conflicts between Tutsis and Hutus dominate the Rwandan history. An estimated one million persons were massacred during the 1994 genocide directed against Tutsis and moderate Hutus. Those who survived suffer from physical and psychological wounds. This is equally true for the survivors of wa
In theory, a perfectly competitive market is a market where there are many suppliers of products, their products are substitutable, all suppliers are price-takers and not price-makers, and there are no significant barriers to market entry. The opposite of perfect competition is total market domination, or monopoly. That is a market where there is only one supplier of products and where significant
