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LundOnline S2O UtaGrothkopf

LundOnline_S2O_UtaGrothkopf_short SUBSCRIBE TO OPEN (S2O) LIBRARIAN’S VIEW ON A COLLABORATIVE OA MODEL Uta Grothkopf Library, Documentation, and Information Services department European Southern Observatory (ESO) LundOnline, 9-10 November 2022 WORK CULTURE IN ASTRONOMY Observatories typically in remote places Community (researchers and librarians) closely connected Tradition of sharing and exchang

https://www.lundonline.lub.lu.se/sites/lundonline.lub.lu.se/files/2022-11/LundOnline_S2O_UtaGrothkopf.pdf - 2026-05-29

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1 Rettsstaten En veiledning for politikere 2 Rettsstaten En veiledning for politikere Copyright © The Raoul Wallenberg Institute of Human Rights and Humanitarian Law og The Hague Institute for the Internationalisation of Law 2012 ISBN: 978-91-86910-74-7 Denne veiledningen distribueres på forutsetning av at den ikke gjennom handel eller på annen måte skal bli lånt ut, solgt, leid ut, eller distribu

https://rwi.lu.se/app/uploads/2016/01/RettsstatenNorsk.pdf - 2026-05-29

Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer

PURPOSE: Several studies have indicated that broad genomic characterization of childhood cancer provides diagnostically and/or therapeutically relevant information in selected high-risk cases. However, the extent to which such characterization offers clinically actionable data in a prospective broadly inclusive setting remains largely unexplored.METHODS: We implemented prospective whole-genome seq

Organic Carbon Burial in Constructed Ponds in Southern Sweden

Small ponds constructed for nutrient retention, biodiversity conservation or recreation also store large amounts of carbon. The potential role of small ponds for carbon storage and greenhouse gas emissions have been highlighted both in the scientific literature and in management plans. The role of small ponds in the global carbon budget is likely significant, but the potential has not been fully eSmall ponds constructed for nutrient retention, biodiversity conservation or recreation also store large amounts of carbon. The potential role of small ponds for carbon storage and greenhouse gas emissions have been highlighted both in the scientific literature and in management plans. The role of small ponds in the global carbon budget is likely significant, but the potential has not been fully e

Severe, life-threatening, and fatal chronic health conditions after allogeneic blood or marrow transplantation in childhood

Background: A comprehensive assessment of morbidity after allogeneic bone marrow transplantation (BMT) performed in childhood remains understudied. Methods: Seven hundred eighty-nine allogeneic BMT recipients who had survived ≥2 years after BMT performed between 1974 and 2014 at age <22 years and 690 siblings completed a 255-item survey self-reporting sociodemographics and chronic health condition

Identifying Abnormal Exertional Breathlessness in COPD : Comparing Modified Medical Research Council and COPD Assessment Test With Cardiopulmonary Exercise Testing

Background: COPD management is guided by the respiratory symptom burden, assessed using the modified Medical Research Council (mMRC) scale, the COPD Assessment Test (CAT), or both. Research Question: What are the abilities of mMRC and CAT to detect abnormally high exertional breathlessness on incremental cardiopulmonary cycle exercise testing (CPET) in people with COPD? Study Design and Methods: A

Inter-rater variability for the American Society of Anesthesiologists classification in patients undergoing hepato-pancreato-biliary surgery (MILESTONE-2) : international survey among surgeons and anaesthesiologists

BACKGROUND: Patients undergoing hepato-pancreato-biliary surgery are typically preoperatively assessed using the American Society of Anesthesiologists (ASA) classification, which is also used for case-mix adjustment when comparing centre outcomes. Studies determining the inter-rater variability of the ASA classification within hepato-pancreato-biliary surgery are currently lacking.METHODS: An inte

In-depth proteomic analysis reveals unique subtype-specific signatures in human small-cell lung cancer

BACKGROUND: Small-cell lung cancer (SCLC) molecular subtypes have been primarily characterized based on the expression pattern of the following key transcription regulators: ASCL1 (SCLC-A), NEUROD1 (SCLC-N), POU2F3 (SCLC-P) and YAP1 (SCLC-Y). Here, we investigated the proteomic landscape of these molecular subsets with the aim to identify novel subtype-specific proteins of diagnostic and therapeut

Complications after proton radiotherapy in children, focusing on severe late complications. A complete Swedish cohort 2008–2019

Background: Proton radiotherapy (RT) is an attractive tool to deliver local therapy with minimal dose to uninvolved tissue, however, not suitable for all patients. The aim was to explore complications, especially severe late complications (grades 3–4), following proton RT delivered to a complete Swedish cohort of paediatric patients aged <18 years treated 2008–2019. Material and Methods: Data was

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In parallel with the changes observed in the world of work, the scope of occupational health and safety should be understood in a way that encompasses psychosocial risks. This necessity stems from the principle that occupational health and safety should be dealt with through a dynamic approach and finds itself a place in the national and international legal order. The scope of this thesis in terms

Incidence and outcomes of acute mesenteric ischaemia : a systematic review and meta-analysis

Objective To estimate the incidence of acute mesenteric ischaemia (AMI), proportions of its different forms and short-term and long-term mortality. Design Systematic review and meta-analysis. Data sources MEDLINE (Ovid), Web of Science, Scopus and Cochrane Library were searched until 26 July 2022. Eligibility criteria Studies reporting data on the incidence and outcomes of AMI in adult populations

Estimation of actual evapotranspiration : A novel hybrid method based on remote sensing and artificial intelligence

Actual evapotranspiration (AET) is one of the decisive factors controlling the water balance at the catchment level, particularly in arid and semi-arid regions, but measured data for which are generally unavailable. In this study, performance of a base artificial intelligence (AI) model, adaptive neuro-fuzzy inference system (ANFIS), and its hybrids with two bio-inspired optimization algorithms, n

Healthcare utilization for somatic conditions among Swedish patients in opioid substitution treatment, with and without on-site primary healthcare

Background: Opioid substitution treatment (OST) populations are aging and have increased mortality and somatic morbidity compared to general populations internationally. While OST patients have poor self-rated physical health and unmet healthcare needs, documented healthcare utilization has been sparsely investigated. The aim of this study was to assess registered healthcare utilization for somati

The leukocyte complexity and mutational landscape of periampullary adenocarcinoma. Morphology matters.

Background: Periampullary adenocarcinomas are a heterogenous group of tumours with poor prognosis that hasnot improved considerably the last decades. Tumour morphology, i.e. intestinal type (I-type) or pancreatobiliarytype (PB-type), has been demonstrated to be a more relevant prognostic factor than anatomical origin. Tumourinfiltrating immune cells are vital in shaping the natural progress of canBackground: Periampullary adenocarcinomas are a heterogenous group of tumours with poor prognosis that hasnot improved considerably the last decades. Tumour morphology, i.e. intestinal type (I-type) or pancreatobiliarytype (PB-type), has been demonstrated to be a more relevant prognostic factor than anatomical origin. Tumourinfiltrating immune cells are vital in shaping the natural progress of can

Cortico-Striatal Oscillations Are Correlated to Motor Activity Levels in Both Physiological and Parkinsonian Conditions

Oscillatory neural activity in the cortico-basal ganglia-thalamocortical (CBGTC) loop is associated with the motor state of a subject, but also with the availability of modulatory neurotransmitters. For example, increased low-frequency oscillations in Parkinson’s disease (PD) are related to decreased levels of dopamine and have been proposed as biomarkers to adapt and optimize therapeutic interven

Trends and factors associated with early initiation of breastfeeding in Namibia : Analysis of the Demographic and Health Surveys 2000-2013

Background: Early initiation of breastfeeding (EIBF) lowers the risk for all-cause mortality in babies, including those with low birth weight. However, rates of neonatal mortality and delayed initiation of breastfeeding remain high in most low- and middle-income countries. This study aimed to assess the trends and factors associated with EIBF in Namibia from 2000 to 2013. Methods: An analysis of E

Genetic anticipation in Swedish Lynch syndrome families

Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS) caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have an earlier onset compared to the general population. However, age at first primary cancer varies wit

Tumor Necrosis Factor Receptor 1 and 2 Are Associated With Risk of Intracerebral Hemorrhage

BACKGROUND AND PURPOSE: Raised plasma concentrations of tumor necrosis factor receptors (TNFR) have been linked to arterial stiffness, cerebral microbleeds, and vascular events. The aim of this study was to investigate the association of circulating levels of TNFR1 and TNFR2 with risk for future intracerebral hemorrhage (ICH).METHODS: The population-based MDCS cohort (Malmö Diet and Cancer Study;

Early prenatal exposure to suspected endocrine disruptor mixtures is associated with lower IQ at age seven

Background: Endocrine disrupting chemicals (EDCs) are xenobiotics with the ability to interfere with hormone action, even at low levels. Prior environmental epidemiology studies link numerous suspected EDCs, including phthalates and bisphenol A (BPA), to adverse neurodevelopmental outcomes. However, results for some chemicals were inconsistent and most assessed one chemical at a time. Objectives:

PreHospital Ambulance Stroke Test - pilot study of a novel stroke test

Background: There is a need for a prehospital stroke test that in addition to high sensitivity for stroke, also is able to communicate stroke severity similar to the National Institute of Health Stroke Scale (NIHSS). Methods: The PreHospital Ambulance Stroke Test (PreHAST), an eight item test based on NIHSS, which scores stroke severity from 0-19 points, was designed and adapted for the ambulance