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We previously reported that soluble decay-accelerating factor (DAF) and coxsackievirus-adenovirus receptor (CAR) blocked coxsackievirus 133 (CVB3) myocarditis in mice, but only soluble CAR blocked CVB3-mediated pancreatitis. Here, we report that the in vitro mechanisms of viral inhibition by these soluble receptors also differ. Soluble DAF inhibited virus infection through the formation of reversi
In their comment piece, van Basshuysen and Brandstedt raise three main issues: first, whether population at the global scale, or individual family planning decisions, are relevant for climate change mitigation; second, they offer useful critiques of the methodologies to attribute greenhouse gas emissions for the choice to have a child; and third, they question the appropriate ethical responsibilit
Despite the benefits of a diverse approach to crop pollination, global food production remains reliant on a low diversity of managed pollinators, especially the European honey bee (Apis mellifera). To facilitate more robust pollinator management and improve the resilience of the production system, it is necessary to understand regional variation in the pollination ecology of global food crops. Wat
Gene amplification is one of the mechanisms for oncogene activation in solid tumors. The size of the amplified regions may vary considerably among individual tumors, and more than one gene may be affected within the same amplicon. The main objective in analyzing genomic amplifications has therefore been to map the shortest region involved and to identify genes with increased expression as a result
Recombinant adeno-associated virus (rAAV) is a mammalian virus that has been altered to be used as a gene delivery vehicle. Several changes to the viral genome have made them replication deficient so that this aspect of the viral infection cycle is under full control of the experimenter, while maintaining gene expression machinery. Over the last decades, rAAVs have become the gold standard for stu
Previous research on variation in patient reported experience measures (PREMs) suggest that it is important to be cautious when using comparative information about patients’ experiences, collected via patient surveys, to assess provider performance. Not all factors associated with variation in PREMs are related to factors that providers themselves can control. This study explores if structural cha
Photomultiplier tube (PMT) nonlinearities relevant for single shot high-speed lifetime phosphor thermometry were investigated by simulating decay curves with a light emitting diode (LED) at repetition rates between 1 Hz and 10 kHz. The PMT gain, LED decay time, and background radiant flux were also varied to investigate their impact on the measured decay time error. Errors in the measured decay ti
Physical exercise during growth affects composition, structure and mechanical properties of bone. In this study we investigated whether the beneficial effects of exercise during the early growth phase have long-lasting effects or not. Female Syrian golden hamsters (total n=152) were used in this study. Half of the hamsters had access to running wheels during their rapid growth phase (from 1 to 3mo
Fluvial floods are commonly studied as an occurrence at the level of a specific basin and are speculated to be closely related to the basin's morphometry. It is possible to identify and rank sub-basins based on how susceptible they are to fluvial flooding events using morphometric criteria. However, one of the key causes that triggers fluvial flooding is the increase in precipitation extremes and
IntroductionCardiac arrest (CA) survivors often face significant health challenges, including insomnia, which can adversely affect their health-related quality of life. The Minimal Insomnia Symptom Scale (MISS) is a brief, self-reported instrument designed to screen for insomnia. This study aimed to identify the measurement properties of the MISS in CA survivors and to explore a relevant cut-off s
Popular Abstract in English Fish are an excellent source of healthy protein and fat in the human nutrition. However, the fisheries cannot supply enough of fish to satisfy the demand of a growing world’s population. Sustainable aquaculture can help feeding the growing world. This business is growing every year, and together with it the fish farms and fish feed factories are growing. This created thAs aquaculture expands, the volume of fish feed produced and transported must also increase. Therefore a better understanding and increased control of the factors that influence the physical quality of feed pellets is required. To achieve this goal, reliable methods measuring the physical quality of feed are needed. The Holmen pellet tester (NHP 100) could be adapted for this purpose, but the spec
