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The Grodsky packet storage model describes many features of insulin release, but at present more or less arbitrary simplifications are necessary. The consequences of various simplifications are discussed, especially with regard to identification of parameters thought to be of importance for glucose tolerance. In particular, the insulin release dynamics of the ordinary intravenous glucose tolerance

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Natural capital has emerged as the dominant response to revaluing nature in the context of deepening ecological degradation. The belief is that we make the contribution of nature to our well-being visible by seeing it as a form of capital alongside human-produced capitals. This would, it is assumed, help correct the observed imbalances between the capitals and prevent further ecological destructio

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The COVID-19 crisis introduced telecommuting and distance schooling into households all around the world. When national authorities enforced mitigation measures, they not only limited the spread of the disease, but also altered the lifestyle of many people. The joint effect of millions of people adapting to the new reality gave rise to an altered residential energy consumption pattern. Knowledge a

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This paper aims to evaluate the effect of the U.S. monetary policy on the bitcoin price. In particular, how monetary policy easing affects the bitcoin returns. One of the main tenets of bitcoin is that it is a hedge against inflation caused by a large increase in the money supply. Inspired by that idea, this study intends to analyze bitcoin’s instant response to the Federal Reserve’s monetary poli

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This paper analyses how large Swedish firms and financial institutions integrate climate change and biodiversity into their business strategies and governance structures. Using unique 2022 and 2023 survey data and logistic probability models, we examine how internal and external factors shape early responses to the EU Taxonomy and the CSRD. Our findings confirm that the integration of climate chan

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During the COVID-19 pandemic, the Swedish Covid Association (SCA) was established to represent individuals with Long COVID (LC). The unique Swedish response to the pandemic, characterized by minimal restrictions, serves as the backdrop for the SCA’s efforts to highlight the specific needs of LC patients, who were largely excluded from pandemic policies and protective measures. Utilizing the Narrat

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Platelets express Toll-like receptor 4 (TLR4), and this has been shown to be responsible for the thrombocytopenia induced by lipopolysaccharide (LPS) administration in vivo. We studied the role of LPS in mediating platelet phagocytosis by THP-1 cells in vitro by flow cytometry. Opsonization of platelets with an IgG monoclonal (W6/32) antibody or with IgG autoantibody-positive sera from patients wi

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Increased platelet destruction is central in the pathogenesis of immune thrombocytopenia. However, impaired platelet production is also relevant and its significance underlies the rationale for treatment with thrombopoietin receptor agonists (TPO-RAs). Previous studies have associated enhanced complement activation with increased disease severity. Additionally, treatment refractoriness has been deIncreased platelet destruction is central in the pathogenesis of immune thrombocytopenia. However, impaired platelet production is also relevant and its significance underlies the rationale for treatment with thrombopoietin receptor agonists (TPO-RAs). Previous studies have associated enhanced complement activation with increased disease severity. Additionally, treatment refractoriness has been de

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This edited collection explores the background and implementation of the Nordic Barnahus (or 'Children's House') model - recognised as one of the most important reforms related to children who are the victims of crime in the Nordic region. This book discusses both its potential to affect change and the challenges facing it. The model was introduced as a response to a growing recognition of the nee