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Objective. To study degree of blood pressure (BP) control in primary healthcare (PHC) treated hypertensive patients in relation to sex, age, drug treatment, and concomitant diseases. Design. Random sample of patients with hypertension. Setting. Ten PHC centres in the Region of Skane, Sweden. Subjects. All the 30- to 95-year-old patients with hypertension who during the period 12 September to 24 Se
Interaction of mono- and disaccharides, polysaccharide particles and yeast cells with boronate-containing copolymers (BCC) of N-acryloyl-m-aminophenylboronic acid (NAAPBA) with NN-dimethylacrylamide (DMAA) or N-isopropylacrylamide (NIPAM) was studied. The binding of saccharides to BCC of NIPAM resulted in a shift of its phase transition temperature (Delta T-p), which provided a quantitative measur
Over the last decades or so, artificial neural networks (ANNs) have become one of the most promising tools for modelling hydrological processes such as rainfall-runoff processes. In most studies, ANNs have been demonstrated to show superior result compared to the traditional modelling approaches. They are able to map underlying relationships between input and output data without detailed knowledge
Under årens lopp har människan gjort stora landvinningar inom läkemedelsforskning, vilket har lett fram till avancerade läkemedel som idag tas för givna. Avancerade läkemedel sätter dock höga krav på tillverkarna av läkemedel, vilket har lett till att framtagandet av nya läkemedel är en ganska komplicerad process. Faktum är att dagens läkemedelsutveckling är så komplex att alla aspekter förmodligePopular Abstract in Swedish Under årens lopp har människan gjort stora landvinningar inom läkemedelsforskning, vilket har lett fram till avancerade läkemedel som idag tas för givna. Avancerade läkemedel sätter dock höga krav på tillverkarna av läkemedel, vilket har lett till att framtagandet av nya läkemedel är en ganska komplicerad process. Faktum är att dagens läkemedelsutveckling är så komplex
The relation between use of sunscreens, different host factors and malignant melanoma was investigated in a population-based, matched case-control study of malignant melanoma in the South Swedish Health Care Region, which has the highest risk for melanoma in Sweden, between 1 July 1988 and 30 June 1990. In total, 400 melanoma patients and 640 healthy controls aged 15-75 years answered a comprehens
Popular Abstract in Swedish Normal hjärnaktivitet är beroende på en delikat balans mellan inhibitorisk och excitatorisk nervcellssignallering. Om denna balans störs och lutar mer åt en ökad excitering uppstår epileptiska anfall. Ungefär 1 % av befolkningen i västvärldens drabbas av epilepsi, framförallt av temporallobs-epilepsi (TLE) vilket är den vanligast förekommande formen av epilepsi bland vuTemporal lobe epilepsy (TLE) is the most common form of epilepsy among adult patients, and the most problematic one as seizures cannot be controlled by currently available drugs in 30 % of patients. Gene therapy based on overexpression of endogenous anti-epileptic agents such as the neuropeptide galanin and the glial cell line-derived neurotrophic factor (GDNF) represents a promising new approach
Objective The aim of this study was to estimate the rate of fetal loss in dichorionic (DC) and monochorionic (MC) twin pregnancies stratified according to zygosity and method of conception. Methods In a prospective multicenter observational study women with a twin pregnancy bad an ultrasound scan before 14 + 6 weeks' gestation in order to determine chorionicity. The fetal loss rate, the perinatal,
Glucagon like peptide 1 (GLP-1) is an incretin hormone released as a bioactive peptide from intestinal L-cells in response to eating. It acts on target cells and exerts several functions as stimulating insulin and inhibiting glucagon. It is quickly deactivated by the serine protease dipeptidyl peptidase IV (DPP-IV) as an important regulatory mechanism. GLP-1 analogues are used as antidiabetic drug
Background The Master’s Thesis Case Study Company is a premium brand automotive OEM. In the Swedish fleet car (or company car) market, the company is lagging behind its main competitors in terms of market share a fact that is not true for several other European markets. Concurrently, the automotive industry is set to go through radical changes the next few years. The speedy development of digitali
OBJECTIVE: To study the association of physician's sex with blood pressure, lipid control, and cardiovascular risk factors in treated hypertensive men and women, stratified for the sex of their physician. METHODS: In a cross-sectional survey of hypertensive patients, 264 primary care physicians (PCPs), 187 men and 77 women from across Sweden, recruited 6537 treated hypertensive patients (48% men)
Popular Abstract in Swedish I avhandlingen redovisas undersökningar av näringsdynamiken hos fem olika lövträdsarter (ask, björk, bok, ek och lind) vilka jämförs med gran, som är ett mycket undersökt trädslag ur närings-synvinkel. Målsättningen med studierna var att klargöra de olika trädslagens näringstillstånd under likartade förhållanden, deras inverkan på och samspel med marken, samt deras näriThis thesis considers several important aspects of nutrient dynamics and allocation in adult stands of Swedish forest tree species (Quercus robur L., Tilia cordata Mill., Fraxinus excelsior L., Betula pendula Roth., Fagus sylvatica L. and Picea abies (L.) Karst) planted on the same soils. Differences between species in macro- (N, P, K, Ca, Mg, S), and micro- (B, Cu, Fe, Mn, Zn) nutrient levels in
Abstract Purpose: The main purpose with this thesis was to describe the complexities involved when public sector organizations initiate changes in their organizational culture. This research also aims to depict how managers in a public organization interpret the implementation of two separate “shared value systems”, that originates from different parts of the organization. Research design: This th
Rätt bakterier i tarmen kan göra det lättare att förbli smal Övervikt är ett stort problem i dagens samhälle. Övervikt och fetma kan kopplas ihop med ett antal sjukdomar som följd av övervikten. Personer med övervikt lider större risk att drabbas av hjärt– och kärlsjukdomar, diabetes typ 2 och även förtidig död. Det är visats av andra forskargrupper att överviktiga barn har en högre risk att själAbstract Problem with obesity is a growing health problem, and young children with obesity and overweight suffer a bigger risk to become overweight as adults. The aim of this study was to compare the differences which arise in the microbiota among preschool children who had participated in an intervention study. The present study includes two groups of children, whom had different body mass index
Effekter av träning i fastande tillstånd Den tydligaste effekten av uthållighetsträning är förbättrad kondition. Ordet kondition kan definieras som samspelet mellan lungor, hjärta, blod och muskler. Lungorna ska växla syrgas från inandningsluften och släppa ut koldioxid. Hjärtat ska pumpa blod till lungorna och ut i kroppen. Blodets uppgift är att syresätta musklerna vid fysisk ansträngning. Allt
På den antarktiska kontinenten finns värdefulla och i princip oexploaterade naturtillgångar. Dess geostrategiska betydelse och potentiella rikedomar gör Antarktis attraktivt för både forskare och företag. Storbritannien gjorde som första land suveräna anspråk på en del av Antarktis år 1908. Flera andra länder följde exemplet, vilket resulterade i ett ökat internationellt intresse för kontinenten.Antarctica is a continent full of natural resources, still almost untouched of the human hand. Geostrategic implications and potential economic wealth make the Continent relevant for researcher as well as profit-seeking industries. In 1908, United Kingdom made claims of a sector of Antarctica. After that, several countries followed, leading the eyes of the world to this remote place. To calm dow
Topiramate is biochemically classified as a fructopyranose sulphamate. Discovered as early as 1979, during middle 1980's it was approved in many countries for the treatment of epilepsies and migraine prevention. More recently, in the experimental stage, possible new indications have been disclosed: treatment of obesity, bipolar disorder, also cessation of smoking, neuropathic pain, cerebral pseudo
Vad består materia av? Det är en fundamental fråga som mänskligheten försökt besvara i tusentals år. Vårt svar på den frågan har utvecklats enormt de senaste 200 åren. Atomer, från grekiskans ord för odelbar, bygger upp materian vi ser omkring oss. Det antogs längeatt atomer verkligen var odelbara, men strax innan sekelskiftet år 1900, kom experimentellt bevis från J. J. Thomson, som påvisade attThe papers in this thesis all concern the treatment of colors in perturbative QCD, both in the context of hard scattering cross sections and for parton showers. The complexity of the color structure of QCD increases quickly with the number of external partons. One way of tackling this issue is by using an orthogonal, group theory based, type of bases, called multiplet bases. This is the topic of p
Pyrimethanil (PYM) is a fungicide used pre- and post-harvest on many crops. It has a low acute toxicity but is of toxicological concern because of its antiandrogenic properties. The aim of the current work was to investigate some metabolism and estimate elimination kinetics of PYM in humans after experimental oral and dermal exposure. A liquid chromatography triple quadrupole mass spectrometry (LC
It is important that climate models can accurately simulate the terrestrial carbon cycle in the Arctic due to the large and potentially labile carbon stocks found in permafrost-affected environments, which can lead to a positive climate feedback, along with the possibility of future carbon sinks from northward expansion of vegetation under climate warming. Here we evaluate the simulation of tundra
