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Background: The Tau PET ligand 18F-AV1451 has been shown to reliably detect paired helical filaments of tau in Alzheimer's disease, but it is not yet known whether it binds to the tau aggregates present in patients with mutations in the gene (MAPT) coding for the tau protein. Further, no study has yet compared the cerebral retention of 18F -AV1451 with the tau aggregates revealed using neuropathol
Background: Both lifestyle and genetic predisposition determine the development of type 2 diabetes (T2D), and studies have indicated interactions between specific dietary components and individual genetic variants. However, it is unclear whether the importance of overall dietary habits, including T2D-related food intakes, differs depending on genetic predisposition to T2D. We examined interaction
Objective: The auditory brainstem response (ABR) is often affected in neurodevelopmental disorders. The aim of this study was to investigate gender differences in ABR between young females and young males with ADHD, compared to control subjects. Method: We studied 63 females with ADHD (mean 13.8 years), 26 female controls (mean 13.8years), 48 males with ADHD (mean 13.1 years), and 20 male controls
A novel pretreatment approach was developed in the present study to simultaneously reduce the content of inorganic troubling elements (TEs) and improve biomass energy density, i.e., combined leaching and steam explosion (SE) pretreatment with mechanical pressing. Three different high-ash-containing biomass feedstocks were studied – wheat straw (WS), spruce bark (SB), and empty fruit bunches of oil
Purpose: This study aimed to investigate whether malnutrition or nutrition impact symptoms (NIS) affect the possibility of returning to work after treatment for head and neck cancer. Methods: Patients of working age with head and neck cancer were followed up from treatment initiation to 3 months (n = 238), 1 year (n = 182), and 2 years (n = 130) after treatment completion. The observed decrease in
Modern office buildings have high energy savings potential and potential for indoor climate improvements. During the nineties many office buildings with glass facades were built, in several cases with double skin glass facades. The advantages of buildings with double skin facades (compared with single skin glazed ones) are considered to be the reduced heating and cooling demand, the increased soun
Mycket forskarmöda har ägnats åt den stora reduktionen i början av 1680-talet, då den svenska adelns förläningar drogs in till kronan och maktbalansen skiftade till den enväldige kungens fördel. Denna forskning har framför allt behandlat den politiska och ekonomiska utvecklingen, ofta ur ett elitperspektiv. Andra gruppers agerande och levda verklighet har sällan blivit belysta, vilket inte minst gA large body of scholarly work has been dedicated to the Swedish reduction in the early 1680s when fiefs granted to the nobility were revoked as the crown strengthened its position. However, this research has focused on political and economic developments from an elite perspective. Insufficient attention has been paid to the actions and lived realities of other groups, not least the servants of th
OBJECTIVE: To investigate potential risk factors behind the increased incidence of necrotising enterocolitis (NEC) in Swedish extremely preterm infants.DESIGN: Registry data from two population-based national cohorts were studied. NEC diagnoses (Bell stage ≥II) were validated against hospital records.PATIENTS: All liveborn infants <27 weeks of gestation 2004-2007 (n=704) and 2014-2016 (n=895) in S
Magnesium (Mg) is a metallic material with a great range of potential applications. It can be used as the lightest structure material in automotive and aviation sectors, medical implants, hydrogen storge, etc. In such applications, oxidation and corrosion reactions play a critical role in the effectiveness of use. Therefore, deeper understanding of the fundamental mechanisms of oxidation and corro
Molecular profiling of extracellular vesicles (EVs) offers novel opportunities for diagnostic applications, but the current major obstacle for clinical translation is the lack of efficient, robust, and reproducible isolation methods. To bridge that gap, we developed a microfluidic, non-contact, and low-input volume compatible acoustic trapping technology for EV isolation that enabled downstream sm
Water is a finite resource and should be given the attention it deserves to reduce its depletion through leakages in pipe systems. The authors implemented pressure management strategies linked to fixed and variable discharge (FAVAD), the burst and background estimate (BABE), and orifice principle methodologies to analyze a two-phased comparative method for applying optimal pressure management and
Syftet med uppsatsen är att undersöka vilken roll allmänna intressen spelar i den svenska miljöprocessen. Vidare avser arbetet redogöra för de förutsättningar under vilka enskilda, organisationer och myndigheter kan företräda sådana intressen. Uppsatsen berör även vilka som beslutar i frågor som rör allmänna intressen. Då det finns en mängd allmänna intressen som kan aktualiseras i svensk rätt harThe aim of this essay is to investigate the role of public interests in Swedish environmental law. Furthermore the essay aims to explain under which circumstances individuals, organizations and government agencies may represent public interests. The essay also discusses the question of who rules in matters concerning public interests. Since a variety of different public interests may occur in Swed
SAMMANFATTNING Examensarbetets titel: Expertis, välvilja och integritet. Kontextens inverkan på hur förtroende uppfattas vid köp av konsulttjänster Seminariedatum: 2013-01-17 Ämne/kurs: FEKH29, Examensarbete i Marknadsföring på Kandidatnivå, 15 högskolepoäng Författare: Fredrik Svensson, Martin Erlandsson, Patrik Johansson Handledare: Lars Carlman Fem nyckelord: Förtroende, konsulttjänster, ABSTRACT Title: Ability, benevolence and integrity. Contextual impact on how trust is perceived in the purchase of consulting services. Seminar date: 2013-01-17 Course: FEKH29, Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 University Credits Points (UPC) or ECTS‐cr) Authors: Fredrik Svensson, Martin Erlandsson, Patrik Johansson Advisor: Lars Carlman Key
Rätt bakterier i tarmen kan göra det lättare att förbli smal Övervikt är ett stort problem i dagens samhälle. Övervikt och fetma kan kopplas ihop med ett antal sjukdomar som följd av övervikten. Personer med övervikt lider större risk att drabbas av hjärt– och kärlsjukdomar, diabetes typ 2 och även förtidig död. Det är visats av andra forskargrupper att överviktiga barn har en högre risk att själAbstract Problem with obesity is a growing health problem, and young children with obesity and overweight suffer a bigger risk to become overweight as adults. The aim of this study was to compare the differences which arise in the microbiota among preschool children who had participated in an intervention study. The present study includes two groups of children, whom had different body mass index
Effekter av träning i fastande tillstånd Den tydligaste effekten av uthållighetsträning är förbättrad kondition. Ordet kondition kan definieras som samspelet mellan lungor, hjärta, blod och muskler. Lungorna ska växla syrgas från inandningsluften och släppa ut koldioxid. Hjärtat ska pumpa blod till lungorna och ut i kroppen. Blodets uppgift är att syresätta musklerna vid fysisk ansträngning. Allt
En fjärdedel av de homosexuella, bisexuella och transpersoner som deltagit i en stor undersökning år 2013 hade blivit utsatta för hot och våld. Personerna utsätts bland annat för att de inte tillhör normen. Enligt straffskärpningsregeln i 29 kap. 2 § 7 p. BrB är det en försvårande omständighet vid bedömningen av straffvärdet om ett motiv för en brottslig gärning varit att kränka en person, folkgA quarter of the lesbian, gay, bisexual and transgender persons participating in a survey in 2013 had been exposed to threat and violence. One of the reasons for them being targeted was that they do not conform to the norm. According to the penalty enhancement provision in Chapter 29, Section 2, Subsection 7 of the Swedish Penal Code if a motive for a crime is to aggrieve a person, ethnic group o
Vilka värden som betraktas som viktiga i ett samhälle förändras över tid. Det gäller också i straffrätten. I uppsatsen inringas straffrättsliga värden, med ledning i intressen, som utifrån förarbeten och lagtext framstår som centrala. Ett skyddsintresse som fått en mer framskjuten position under den senare delen av nittonhundratalet är personlig integritet. I detta ligger anspråk på autonomi, frihThe values that are considered important in a society change over time. This also applies to criminal law. The paper identifies values, from interests, in criminal law that appear to be central based on the preparatory work and legal text. One protection interest that gained a more prominent position during the latter part of the twentieth century is personal integrity. This includes claims to aut
Background: Cardiovascular disease is common and it is therefore important to have tools to investigate pathophysiology and normal physiology of the cardiovascular system. One such tool is using cardiovascular magnetic resonance in order to measure blood flow in vessels, particularly while the participant imaged is exercising. This enables studying the blood flow during exercise which is especiall
The European spruce bark beetle is an insect that is often referred to as a pest. Responsible for the destruction of over 150 million m3 of Norwegian spruce forest in Europe over the last 50 years makes this insect one of the major disturbances to the forest industry. With global warming at large, changes of the distribution of the bark beetle have emerged with large outbreaks now regularly occurr
