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Identification and isolation of cardiomyocytes from the heart, embryonic stem cells, or induced pluripotent stem cells is a challenging task and will require specific isolation techniques. Less than 30% of the cells within the murine heart are cardiomyocytes and, what is more, there are multiple sub-populations of cardiomyocytes like atrial, ventricular and conduction system cardiomyocytes. In Pap
Background: The presence of echolucent carotid plaques as defined by low ultrasound grey-scale median (GSM) is associated with a higher risk of stroke and myocardial infarction. Betablockers have shown possible anti-atherosclerotic effects. The aim of the present study was to determine if there is an association between carotid plaque GSM and treatment with betablockers. Methods: The GSM of the ca
OBJECTIVE: To study the association of physician's sex with blood pressure, lipid control, and cardiovascular risk factors in treated hypertensive men and women, stratified for the sex of their physician. METHODS: In a cross-sectional survey of hypertensive patients, 264 primary care physicians (PCPs), 187 men and 77 women from across Sweden, recruited 6537 treated hypertensive patients (48% men)
Problem The procurement of a complete factory, including the design, manufacturing and installation, is a common way for automotive producers when acquiring new production equipment for new models. Due to the long lead times of a procurement process, the process has to commence well before the finalisation of the design of the car to be built. This makes the formulation of requirements very comple
Abstract Purpose: The main purpose with this thesis was to describe the complexities involved when public sector organizations initiate changes in their organizational culture. This research also aims to depict how managers in a public organization interpret the implementation of two separate “shared value systems”, that originates from different parts of the organization. Research design: This th
As eutrophication of lakes and oceans is increasing, regulations regarding phosphorus effluents becomes stricter. Consequently, the majority of Sweden’s wastewater treatment plants employs some method for phosphorus removal. Increased efforts for sustainable purification methods has also led to phosphorus removal by chemical means starting to be replaced by biological phosphorus removal. A common
On 1 April 2015, the EU milk quotas were abolished after 30 years in force. The purpose of this paper is to assess the Intra-Union trade effects of the reform, using the gravity model of trade. In particular, the aim is to find out whether competitive Member States have started to export more dairy products as compared to the non-competitive Member States following the reform. In order to perfor
Uppsatsen redogör för rättsreglerna kring omplacering och turordning vid arbetsbristuppsägningar. Det finns ett omfattande regelverk kring anställningsskyddet i Sverige. Det reglerar hur arbetsgivare ska uppträda då uppsägningar ska äga rum. Det krävs saklig grund för att en arbetsgivare ska ha rätt att säga upp en arbetstagare. Detta framgår tydligt ur 7§ anställningsskyddslagen. För att sakligThis essay describes the legal rules regarding relocation and order of priority in connection with termination of employment due to redundancy. There are comprehensive regulations on employment protection in Sweden. It regulates how employers should act when the redundancies will take place. It requires grounds for dismissal for an employer to have the right to terminate an employee. This is evid
Soil temperature (Ts) change is a key indicator of the dynamics of permafrost. On seasonal and interannual timescales, the variability of Ts determines the active-layer depth, which regulates hydrological soil properties and biogeochemical processes. On the multi-decadal scale, increasing Ts not only drives permafrost thaw/retreat but can also trigger and accelerate the decomposition of soil organ
Background: Problem gambling is a public health issue affecting both the gamblers, their families, their employers, and society as a whole. Recent law changes in Sweden oblige local and regional health authorities to invest more in prevention and treatment of problem gambling. The economic consequences of gambling, and thereby the potential economic consequences of policy changes in the area, are
Background: Despite substantial progress in the field of mass spectrometry, there remain barriers to measuring the extracellular vesicles (EVs) proteome in blood plasma. Recent work has shown that isolating EVs can make it possible to detect proteins that have low abundance in plasma. Commonly used EV isolation methods either require large sample volumes and long ultracentrifugation times, or else
Background: Somali women suffer from one of the highest maternal mortality rates in the world. Somalia characterises a specific low-income country situation with a mix of newly urbanized and nomadic culture combined with a frail health care infrastructure set in a post-conflict era. Very little is known about the effects that these contextual factors can have on maternal mortality. Objectives: To
We investigated the relationship between the affective component (A: the level of offensiveness/intensity) and the behavioral component (B: the frequency of usage) of taboo words that are part of an individual’s natural language (C: the cognitive component). In Study 1, 900 US-residents generated the 10 most common taboo words they use in their daily lives (C). In Study 2, 1000 US-residents were pWe investigated the relationship between the affective component (A: the level of offensiveness/intensity) and the behavioral component (B: the frequency of usage) of taboo words that are part of an individual’s natural language (C: the cognitive component). In Study 1, 900 U.S. residents generated the 10 most common taboo words they use in their daily lives (C). In Study 2, 1,000 U.S. residents w
The relation between use of sunscreens, different host factors and malignant melanoma was investigated in a population-based, matched case-control study of malignant melanoma in the South Swedish Health Care Region, which has the highest risk for melanoma in Sweden, between 1 July 1988 and 30 June 1990. In total, 400 melanoma patients and 640 healthy controls aged 15-75 years answered a comprehens
It is important that climate models can accurately simulate the terrestrial carbon cycle in the Arctic due to the large and potentially labile carbon stocks found in permafrost-affected environments, which can lead to a positive climate feedback, along with the possibility of future carbon sinks from northward expansion of vegetation under climate warming. Here we evaluate the simulation of tundra
Purpose: High plasma copeptin, a marker of vasopressin, predicts diabetes mellitus. We tested if copeptin could be suppressed by increased water intake in healthy individuals, and if a water-induced change in copeptin was accompanied by altered concentrations of glucose, insulin or glucagon. Methods: Thirty-nine healthy individuals underwent, in random order, 1 week of high water intake (3 L/day o
Although atmospheric 222radon (222Rn) activity concentration measurements are currently performed worldwide, they are being made by many different laboratories and with fundamentally different measurement principles, so compatibility issues can limit their utility for regional-to-global applications. Consequently, we conducted a European-wide 222Rn ∕ 222Rn progeny comparison study in order to eval
Previous research has established that when engaged in episodic memory retrieval, people frequently look at locations associated with the sought-after memory trace, even if those locations no longer contain any information. While it has been further demonstrated that gaze positions showing compatibility between encoding and retrieval increase the likelihood of successful remembering (Johansson &amPrevious research has established that when engaged in episodic memory retrieval, people frequently look at locations associated with the sought-after memory trace, even if those locations no longer contain any information. While it has been further demonstrated that gaze positions showing compatibility between encoding and retrieval increase the likelihood of successful remembering (Johansson &am
Solid grafts of autologous superior cervical ganglia (SCG) or fetal locus coeruleus (LC) were implanted unilaterally into a fimbria-fornix lesion cavity adjacent to the hippocampal formation after a 6-hydroxydopamine lesion of the intrinsic noradrenergic system. Twelve to 15 months after transplantation, one microdialysis probe was implanted in the dorsal hippocampus ipsilateral to the graft, and
Pancreatic cancer is an aggressive malignancy that carries a high mortality rate. A major contributor to the poor outcome is the lack of effective molecular markers. The purpose of this study was to develop protein markers for improved prognostication and noninvasive diagnosis. A mass spectrometry (MS)-based discovery approach was applied to pancreatic cancer tissues and healthy pancreas. In the v
