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The fight between a human host and a bacterial pathogen is highly complicated; each party tries to outshine the other in the race for survival. In humans, the innate immune system-in particular the complement system-functions as the first line of defence against invading pathogens. During the course of evolution, however, pathogens, in order to survive and perpetuate within a host, developed multi

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Decadal-scale variations in total organic carbon (TOC) concentration in lake water since AD1200 in two small lakes in southern Sweden were reconstructed based on visible-near-infrared spectroscopy (VNIRS) of their recent sediment successions. In order to assess the impacts of local land-use changes, regional variations in sulfur, and nitrogen deposition and climate variations on the inferred chang

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The circadian clock measures time across a 24h period, increasing fitness by phasing biological processes to the most appropriate time of day. The interlocking feedback loop mechanism of the clock is conserved across species; however, the number of loops varies. Mathematical and computational analyses have suggested that loop complexity affects the overall flexibility of the oscillator, including

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Popular Abstract in Swedish Avhandlingen presenterar en experimentell studie av urlakning av betong orsakat av vatten som tränger igenom betongen, eller av diffusion av joner till vatten på uppströmssidan. Urlakningsförloppet och dess effekter modelleras med finita-element-metoden.The present report presents an experimental study of leaching of concrete caused by water percolating through the concrete, or by diffusion from concrete to external water in contact. An apparatus was designed and constructed in which de-ionised water could be forced, by external pressure, through a number of concrete specimens of differing characteristics. It was found that, whereas the initial w

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By comparing the cerebrospinal fluid (CSF) proteome between Alzheimer's disease (AD) patients and controls, it may be possible to identify proteins that play a role in the disease process and thus to study the pathogenesis of AD. Two-dimensional gel electrophoresis (2-DE), SYPRO Ruby staining and mass spectrometry were used for clinical screening of disease-influenced CSF proteins in AD patients c

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Background: Effects following a hip fracture often lead to functional disabilities and increased dependence on others. Although persons sustaining a hip fracture constitute a heterogeneous group in Swedish health care, they tend to be treated as a homogenous one. Aim: The aim of this study was to reveal how previously healthy people, aged 65 years and older, described how they had adapted to daily

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Abstract The aim of this study was to investigate how people with chronic pain experience their daily doing, with a special focus on possible adjustment to pain and altered life conditions in order to cope with pain and maintain well-being. In-depth interviews were guided by themes concerning daily occupation, ways to maintain well-being, and future expectations. Using qualitative content analysis

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Laser wakefield electron acceleration in the blow-out regime and the associated betatron X-ray radiation were investigated experimentally as a function of the plasma density in a configuration where the laser is guided. Dielectric capillary tubes were employed to assist the laser keeping self-focused over a long distance by collecting the laser energy around its central focal spot. With a 40 fs, 1

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Sustainable development is a concept that can be interpreted and understood in many different ways. Given that the concept in itself does not provide specific guidance to what is to be achieved, how or when, actors who claim to work with sustainable development needs to know what sustainable development is to them. NGO’s are seen as one group of many actors who are responsible of implementing sust

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Most cochlear implant (CI) strategies are optimized for speech characteristics while music enjoyment is signicantly below normal hearing performance. In this thesis, electrical stimulation strategies in CIs are analyzed for music input. A simulation chain consisting of two parallel paths, simulating normal hearing conditions and electrical hearing respectively, is utilized. One thesis objective is

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An extensive part of the Swedish roads are low-traffic roads, which are not properly constructed and thus lack the necessary bearing capacity. The Swedish Transport Administration has a limited budget each year that is used to fix the roads with the comprehensive needs. Therefore, it is important to be able to make a quick inventory of the existing damages in order to make road maintenance more co

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Environments with a high number of systems that are dependent on each other create complexity in the testing of each system. For a test to perform correctly, every dependency has to be fully functional. If this condition is not met, the test will fail and measures need to be taken into the systems that are causing the problem before it can be repeated again. This is a problem that the test departm

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After a brief introduction to the current general milk industry, the emergence of oat milk is presented, as well as shifting trends in milk consumption. This study aims to analyze oat milk precisely. The analysis is done in terms of packaging. Therefore, oat milk packaging and all the packaging elements were analyzed. After a literature review of Consumer Perception, Consumer Motivation, Consume

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The current refugee crisis can be said to have affected not only actual borders, but also borders within subjectivities. With a poststructuralist and deconstructive approach, subjectivities are recognized as constructed through language and within discourse, and in turn, induced through policy. Thus, in order to examine the discursive construction of subjectivities, this thesis critically engage w

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Many models beyond the Standard Model that predict the existence of multiple Higgs bosons. In general, some of these additional Higgs bosons could be quasi-degenerate in mass either to each other or to the observed 125 GeV Higgs boson. The goal of this thesis is to study under which circumstances we can resolve such Higgs bosons. We first make the simplifying assumption that the observed and predi

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This thesis contributes to the exploration of business models with an aspect of change, by ap- plying the concept of dynamic capabilities. The aim is to explore how entrepreneurial firms utilise dynamic capabilities in order to create resilient business models in times of technological change and uncertainty. Therefore, a multiple case study was conducted on the lab-grown food and dairy industry.

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This thesis aims to show the prospect of capacitance measurements over nanowire arrays as an evaluation method of the p-doping level in weakly p-doped p-n nanowires. The premise of the method is that there will be a high yield of statistical data regarding the doping level of the nanowires. The majority of the work carried out and presented in this thesis is however aimed at the manufacturing of a

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In the background of intensifying global climate change and rapid urbanisation, the frequent occurrence of extreme hydrological events and the increase in surface pollution pose serious challenges to the environmental quality of water bodies. Moreover, with the significant increase in public awareness of environmental protection, higher demands have been placed on water quality monitoring techniqu

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The phenomenon of global framework agreements has emerged through the difficulties of regulating the global labour market where the multinational enterprises' operations have been driven by an economic agenda and profit. The challenges of creating transnational legislation have brought social actors, such as the United Nations and the International Labour Organisation, to initiate self-regulat

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This thesis analyzes lived experiences from former juku students as well as promotional material produced by three shingakujuku (Nichinōken, Yotsuya Ōtsuka, Sapix) aimed at the private junior high school entrance examinations in Japan. The research questions aims to investigate the framing of the future and outcome of attending juku as well as how former students reflect on their own experience an