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The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit
Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytosed by eosinophils, and ECP was released into the phagosomes as judged by immunoel
The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl
In the equation for thermal energy output from a flat-plate solar collector (written as a function of the collector mean heat carrier temperature), both the gain and the loss terms are multiplied by the collector efficiency factor, F'. For a concentrating collector with an uneven (non-uniform) irradiation on the absorber, the efficiency factor for the gain term, here called the optical efficiency
The M protein of Streptococcus pyogenes is a major bacterial virulence factor that confers resistance to phagocytosis. To analyze how M protein allows evasion of phagocytosis, we used the M22 protein, which has features typical of many M proteins and has two well-characterized regions binding human plasma proteins: the hypervariable NH2-terminal region binds C4b-binding protein (C4BP), which inhib
The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, wh
The nonobese diabetic (NOD) mouse spontaneously develops autoimmune-mediated diseases such as diabetes and Sjögren′s syndrome. To investigate whether NOD genes also promote autoimmune-mediatedarthritis we established a NOD strain with an MHC class II fragment containing the Aq class II gene predisposing for collagen induced arthritis (NOD.Q). However, this mouse was resistant to arthritis in contr
BACKGROUND: The overall incidence of colorectal carcinoma is declining in Western populations; however, single country series demonstrate an increase in young-onset (<50 years) colorectal carcinoma. OBJECTIVE: The purpose of this study was to determine whether the pattern of increasing incidence of young-onset colorectal carcinoma is consistent across 3 Western populations. DESIGN: This is a popul
Abstract på spanskaUna de las fuentes más sólidas de nuevo conocimiento sobre las categorías tipológicas proviene de nuestro creciente entendimiento de las lenguas indígenas de América del Sur, una región que hasta hace poco ha estado significativamente subrepresentada en los estudios tipológicos. Este artículo ofrece un ejemplo a través de la investigación del número en nadëb, un miembro de la peOne of the most robust sources of fresh insights into typological categories comes from our growing knowledge of the indigenous languages of South America, a region that until recently has been significantly under-represented in typological studies. This paper offers a case in point through the investigation of number in Nadëb, a member of the small Naduhup family of the northwest Amazon, which re
Naturvetare på Danske Bank 2013-10-16 2 Agenda • Vad gör Naturvetare när dom blir stora? • Vad är Danske Bank? • Vad gör Naturvetare på Danske Bank? • Crash Course in Derivative Pricing! 10/16/13 3 Vad blev mina Vänner när dom blev stora? 10/16/13 Namn Kurser Jobb Sebastian Åberg Ma, Fy, MatStat, Ekon, PhD Analytiker på Bank Kristoffer Grekiska, Ma, Fy, PhD Patent-Ing. DK Kalle Ma, Fy Forsknings-I
https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kandidatprogram/Kandidatdagen/SebastianAAbergKD2013.pdf - 2026-07-09
Graphite electrode modified with laccase from Cerrena unicolor served as a biosensor for detection of 30 phenolic compounds with different structures. Some correlations of the sensor response to the structures of substrates are discussed. This biosensor responded to: (i) nanomolar concentrations of some of the selected phenolic compounds, e.g., 2,6-dimethoxyphenol,coniferyl alcohol, caffeic acid,
https://goteborgonline-my.sharepoint.com/personal/peter_jonsson_educ_goteborg_se/Documents/C%20e%20n%20t%20r%20a%20l%20a%20%20%20S%20a%20c%20o%20r%20å%20d%20e%20t%20%20%20i%20%20%20G%20ö%20t%20e%20b%20o%20r%20g%20s%20%20%20S%20t%20a%20d/AU/SKOT/C%20E%20N%20T%20R%20A%20L%20A%20%20%20S%20A%20C%20O%20R%20Å%20D%20E%20T%20%20%20I%20N%20F%20O%20R%20M%20E%20R%20A%20R/December%202024/www.saco.se/goteborg
Urban transport network is a social space in which agents interact with multiple artifacts –signs, speed bumps, bridges, other vehicles, etc.– As Latour states, the study of social spaces needs to be “materialized”, in this case, considering the material infrastructure that allows –or not– the fluid use of the system, as a fundamental part of the analysis of the transport phenomenon. From an agent
Tidplan-DESS-Rigg_250905.xlsx C:\Users\Anders\Documents\DESS\04 Planering\Tidplan-DESS-Rigg_250905 DESS-Rigg - Återställning 2024-2025-2026 Anders Dahl 2025-09-05 Projektresurser LTH Anders D, Jens, Christer, Anders O Ecergy Per N Afry Tara Sabzevari Leverantörer Bricon, APQ-el, Rörläggaren, Assemblin, L&M Golv Skanska, Tunga Lyft, KompAuto, Atlas Copco, Ecergy OK, aktivitet pågår X Beroende av Ri
https://www.energy.lth.se/sv/sites/energy.lth.se.sv/files/2025-09/Tidplan_DESS_2024-2025_250905.pdf - 2026-07-10
This master thesis examines a space issue in compact living and results in a transformable chair that also can serve as a bench. A big part of the project is the complex and creative way for the designer to fi nd his form language. Th is report looks closer on compact living, furniture in general, the chair especially, trends, infl uences from the furniture industry, carpentry and related subjects
Recent work from several laboratories has demonstrated that proteolytic mechanisms significantly contribute to the molecular interplay between Streptococcus pyogenes, an important human pathogen, and its host. Here we describe the identification, purification and characterization of a novel extracellular cysteine proteinase produced by S.pyogenes. This enzyme, designated IdeS for Immunoglobulin G-
Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotics currently in clinical use have been rendered ineffective due to the rapid spread of antimicrobial resistance among gonococci. The developmental pipe
