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Group A streptococci induce stronger M protein-fibronectin interaction when specific human antibodies are bound

Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and dominance on the bacterial surface. Antibody responses targeting the M protein have been shown to favor the conserved C region. Such antibodies (Abs) c

IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection

Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the effect of pooled immunoglobulins (IgG) on the course of disease in a mouse model of intragastric E. coli O157:H7 inoculation. Intraperitoneal administrat

Development and validation of a machine learning-based model to predict isolated post-challenge hyperglycemia in middle-aged and elder adults : Analysis from a multicentric study

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

Resting-State Electroencephalogram Complexity Is Associated With Oral Ketamine Treatment Response : A Bayesian Analysis of Lempel–Ziv Complexity and Multiscale Entropy

Introduction: Subanesthetic doses of ketamine are a promising novel treatment for suicidality; however, the evidence for predictive biomarkers is sparse. Recently, measures of complexity, including Lempel–Ziv complexity (LZC) and multiscale entropy (MSE), have been implicated in ketamine's therapeutic action. We evaluated electroencephalogram (EEG)-derived LZC and MSE differences between responder

Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h

Cliticisation in the acquisition of French as L1 and L2

The intense debate on continuity in child grammars has largely focused on the existence of Functional Categories (FCs) in early grammars despite differences in language use with adults (e.g., omissions, word order errors, lack of case marking). Simplified, the major theoretical explanations for these properties range from Maturational accounts (Radford 1990 and later) claiming an initial absence o

Rola El-Husseini Dean

Docent | Universitetslektor Kontaktinformation E-post: rola [dot] el-husseini_dean [at] svet [dot] lu [dot] seOrganisation Statsvetenskapliga institutionen Hämtställe: 31 WebbplatsRola El-Husseini Deans profil i Lunds universitets forskningsportalAndra roller Forskare Centrum för Mellanösternstudier (CMES) Universitetslektor Statsvetenskapliga institutionen Medlem i Strategiskt forskningsområde ME

https://www.svet.lu.se/rola-el-husseini-dean - 2026-05-03

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Nyhetsbrev från Akademikerföreningen Sveriges Ingenjörer vid Siemens Energy AB Kontakt: asi.se@siemens-energy.com Redaktörer: SvE, CH, JH Nr: 01 2023-01-19 Möt en styrelseledamot Jag heter Jonas Hylén och är med i styrelsen sedan 1998. Redan på högskolan var jag engagerad i studentråd och lovade mig själv att aldrig engagera mig fackligt igen! Fick ändra mig eftersom arbetet i styrelsen för ASI ge

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/siemens-energy-ab/nyhetsbrev/asi-nyhetsbrev-0123.pdf - 2026-05-03

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Abstract på SpanskaEl artículo aborda el fenómeno del cambio lingüístico a través del aumento del uso de anglicismos en el español contemporáneo. Se fundamenta en la idea de que el significado lingüístico de los anglicismos incluye tanto elementos ideacionales como interpersonales en términos de Halliday (1973). El objetivo es analizar, desde una perspectiva diacrónica y sociolingüística, la incorThe article addresses the phenomenon of linguistic change through the increasing use of Anglicisms in contemporary Spanish. It is grounded in the idea that the linguistic meaning of Anglicisms encompasses both ideational and interpersonal elements, as outlined by Halliday (1973). The objective is to analyze the incorporation of following four Anglicisms in the Spanish-speaking world from a diachro

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Nyhetsbrev från Akademikerföreningen Sveriges Ingenjörer vid Siemens Energy AB Kontakt: asi.se@siemens-energy.com Redaktörer: SvE, MP, SJ Nr: 06/24 2024-09-12 GRIP to Mercer, G2M Mercer är vårt nya system för att klassificera samtliga befattningar för tjänstemän på företaget. Mercer ersätter vårt tidgare system, GRIP, och efter den 12 september har alla tjänstemän en ny befattningskod synlig i Coi

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/siemens-energy-ab/nyhetsbrev/asi-nyhetsbrev-0624.pdf - 2026-05-03

Förhandlingsunderlag Avseende Statlig Visstidanställning (STAVA)

Sektionen HR Mall för 11 § MBL-förhandling avseende statlig visstidsanställning Förhandlingsunderlag avseende en statlig visstidsanställning Berörd verksamhet/ Kostnadsställe/institution el motsvarande Anställningens organisatoriska placering/ Kostnadsställe/institution el motsvarande Ansvarig arbetsgivarföreträdare/ Namn, befattning: Utöver vad som följer av bestämmelserna i lag (1982:80) om anst

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2025-12/F%C3%B6rhandlingsunderlag%20avseende%20statlig%20visstidanst%C3%A4llning%20(STAVA).pdf - 2026-05-03

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Abstract In the present thesis the development and subsequent implementation of the Didactic Models 1 and 2 of the Subjunctive is described. The models focus on the use of a question, with which the student makes the most adequate mode choice for each case. The model unifies perspective and meaning used with the subjunctive from a cognitive perspective, appealing to the inherent representational c

MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec

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Assessing the Article 33 (2-3) framework required under the Convention on the Rights of Persons with Disabilities Anna Bruce February 2024 Author: Anna Bruce This study was commissioned by the Swedish Institute for Human Rights (Institutet för mänskliga rättigheter) and delivered by the Raoul Wallenberg Institute of Human Rights and Humanitarian Law 12 February 2024. The author is grateful to Karo

https://rwi.lu.se/wp-content/uploads/2026/02/Assessing-the-Article-33-2-3-framework-required-under-the-Convention-on-the-Rights-of-Persons-with-Disabilities.pdf - 2026-05-02

The Dynamics of Agglomeration Externalities along the Life Cycle of Industries

Abstract in UndeterminedThe dynamics of agglomeration externalities along the life cycle of industries, Regional Studies. This paper investigates the changing roles of agglomeration externalities along the industry life cycle. It is argued that industries have different agglomeration needs in different stages of their life cycles because their mode of competition, innovation intensity, and learnin

El elogio irónico : la conciencia de lo erotikon como prueba de rectitud moral

Abstract in SpanishSe ha dicho a menudo que la Cronografía de Miguel Psellós, el prolífico autor del s. xi, es una obra historiográfica que semeja una novela y que Psellós gasta mucho tiempo en describir caracteres y en tomar actitudes irónicas respecto de sus protagonistas imperiales. Este artículo sostiene que una versión más refinada de esto puede ser vista en el libro sexto de Psellós a proIt has often been stated that the Chronographia by the eleventh-century prolific author Michael Psellos is a piece of historiography that reads almost like a novel, and that Psellos spends much time on describing characters and taking ironical stances towards his imperial protagonists. This article claims that a refined version of this may be seen in Psellos’ book six on Constantine IX Monomachos.

The assessment of patent pools under antitrust law, a comparative analysis

Denna uppsats behandlar de konkurrensrättsliga skillnaderna i EU-rätt och amerikans rätt rörande patentpooler. Genom patentpooler ges företag möjlighet att gemensamt samla sina patent inom ett visst tekniskt område och tillsammans licensera dem. Genom poolning av patent ökar möjligheterna för snabb utveckling samtidigt som licenskostnaderna minskar då samtliga nödvändiga patent blir tillgängliga gThis thesis identifies the differences in the antitrust regulations concerning patent pooling within the EU and the U.S. Patent pooling enables firms to jointly licence their patents as a package, gathering patents that are necessary in order to produce a certain product. Patent pooling allows faster development at lower costs, since firms can attain all necessary patents through one single licens