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Introduction: The development and optimization of methods for multi-radionuclide measurements in preclinical in vivo and ex vivo SPECT imaging could potentially improve studies in which more than one pharmaceutical is being investigated. The aim of this study is to quantitatively compare and evaluate different methods for these types of measurements using three different modalities – a small anima
Based on the randomised Euro-EWING99-R1 trial, vincristine, adriamycin, cyclophosphamide (VAC) may be able to replace vincristine, adriamycin, ifosfamide (VAI) in the treatment of standard-risk Ewing sarcoma. However some heterogeneity of treatment effect by gender was observed. The current exploratory study aimed at investigating the influence of gender on treatment efficacy and acute toxicity.
Protein G is a streptococcal cell wall protein with separate and repetitively arranged binding domains for immunoglobulin G (IgG) and human serum albumin (HSA). In this work, the binding of protein G to HSA was studied. The results suggest that a single binding site is present on HSA: the apparent size of the HSA-protein G complex (230 kDa) corresponded to two or three HSA molecules bound to one p
Background: Understanding patients' goals and values is important to ensure goal-concordant care; however, such discussions can be challenging. Little is known about the impact of having these discussions on hospitalists. Objective: To assess the impact on hospitalists of a system that reminds them to have serious illness conversations with their patients identified with potential unmet palliative
Objectives: Bacteremia is an acute severe infection with high mortality. Changes in healthcare services and coinfections with SARS-CoV-2 may have affected the mortality for bacteremia during the COVID-19 pandemic, which has been reported for other major diseases. In this study we examine the all-cause bacteremia mortality amidst the COVID-19 pandemic. Methods: A population-based cohort study compr
This study focuses on quantitative long-term effects of SupplementalInstruction (SI) in terms of graduation and dropout rates. One of the main aimsof SI is to introduce students to effective study strategies and techniques. If SIis introduced at an early stage for new students in higher education, it shouldtherefore be expected that this action will promote timely graduation. This hasalso been ind
Denna serie (ISBN 978-91-986003-0-8) innehåller den litauenjudiske statsmannen, folkrättsjuristen och sionistiske diplomaten Shimshon Rosenbaums (1859–1934) samlade verk på originalens språk med fullständiga översättningar till engelskan. I band 1 återges hans skrifter om folkrätt, sionism samt den judiska nationens självbestämmande, autonomi och statlighet.
Problem: Refugee entrepreneurship has recently garnered a growing academic and political interest around the world. The rate of scientific publication has soared in the last few years due to the scholarly urgency on the topic following the ‘global refugee crises’. Nevertheless, the research field is currently underdeveloped with existing knowledge dispersed across various and often disconnected di
Background: For a significant proportion of the older population, increasing age is associated with health problems and worsening health. Older family caregivers are largely responsible for care of next-of-kin living at home, which impacts their own physical and mental health both positively and negatively. However, evidence is insufficient regarding the health situation of older caregivers. The a
The substitution of scandium in fullerene single‐molecule magnets (SMMs) DySc2N@C80 and Dy2ScN@C80 by lutetium has been studied to explore the influence of the diamagnetic metal on the SMM performance of dysprosium nitride clusterfullerenes. The use of lutetium led to an improved SMM performance of DyLu2N@C80, which shows a higher blocking temperature of magnetization (TB=9.5 K), longer relaxation
Background The need for psychotherapy in primary health care is on the increase but individual-based treatment is costly. The main aim of this randomised controlled trial (RCT) was to compare the effect of mindfulness-based group therapy (MGT) with treatment as usual (TAU), mainly individual-based cognitive behavioural therapy (CBT), on a broad range of psychiatric symptoms in primary care patient
In 2009-2014, dose surveys aimed to collect adult patient data and parameters of most common radiographic examinations were performed in six Russian regions. Typical patient doses were estimated for the selected examinations both in entrance surface dose and in effective dose. 75%-percentiles of typical patient effective dose distributions were proposed as preliminary regional diagnostic reference
The aim of this paper was to explore the effect of seasonal temperature differences and cold indoor environment in winter on the physical performance of older people living in the community based on a field study. We recruited 162 home-dwelling older people from a rehabilitation facility in the Osaka prefecture, Japan; physical performance data were available from 98/162 (60.5%). At the same time,
The article treats the experience of Swedish designers, architects and sculptors, who travelled to Pompeii over some 200 years, from the 1760s to the 1920s, and their subsequent appropriation of the Pompeian idiom for creations in Stockholm and surroundings. It puts forth that the kind of premises found appropriate for decorations in Pompeian derivation varied over time, from Royal pleasure housesThe article treats the experience of Swedish designers, architects and sculptors, who travelled to Pompeii over some 200 years, from the 1760s to the 1920s, and their subsequent appropriation of the Pompeian idiom for creations in Stockholm and surroundings. It puts forth that the kind of premises found appropriate for decorations in Pompeian derivation varied over time, from Royal pleasure houses
Abstract: Purpose Ingrowth of fibroblasts in a polypropylene mesh may cause contraction and a later recurrence. We assessed mesh contraction in intraabdominal and retromuscular implantation after incisional hernia repair. Methods: A cohort of patients within an RCT on laparoscopic (LHR) versus open hernia repair (OHR) had their mesh borders marked with metal clips. X-ray was performed on postopera
Background. Philadelphia chromosome positive (Ph+) ALL accounts for 3-5% of pediatric ALL. An international survey on 640 children diagnosed between 1995 and 2005 and treated with chemotherapy and stem cell transplantation (SCT) without the use of tyrosin kinase inhibitors (TKI) recently reported an overall 7-year event free survival (EFS) and overall survival (OS) of 31.2% and 44.2%, respectively
The genes for semenogelin I and II, the major protein constituents of the human seminal fluid, have been characterized by three overlapping clones in bacteriophage lambda, encompassing 31.5 kilobases (kb) of genomic DNA. The two genes are located 11.5 kb apart in the region q12-q13.1 on chromosome 20. Both genes are relatively compact, spanning only 2.7 and 3.1 kb, respectively. The transcription
Objective: Generic substitution has contributed to economic savings but switching products may affect patient adherence, particularly among those using multiple medications. The aim was to analyse if use of multiple medications influenced the association between switching products and refill adherence to angiotensin-converting-enzyme (ACE) inhibitors in Sweden. Study Design and Setting: New users
Nordic Walking is an exercise form requiring significant energy consumption, but where the use of poles minimizes the risk of injury. The aim of this pilot study was to examine the effect of 3 months of Nordic Walking on males (>40 years of age) with haemophilia, regarding joint function (Haemophilia Joint Health Score), physical ability (Haemophilia Exercise Project - Test-Questionnaire), exercis
