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We present a detailed investigation into a source of distortion that affects the classic bootstrapped switch. Our analysis reveals that the transition phase between track mode and hold mode is a critical factor in causing the distortion. To address this issue, we propose a novel technique that effectively mitigates the problem. Our results, based on simulations conducted using a 22-nm FDSOI CMOS p
This paper presents the design and comparison of an active Gm-C and a passive baseband filter for 6G applications. Both presented circuits are 5th-order differential low-pass filters with 3-dB cut-off frequencies of 4.9 and 4.7 GHz, respectively, implemented in a 22 nm FD-SOI CMOS technology. The active filter uses back-gate tuning to optimize the transfer function, and achieves a measured in-band
INTRODUCTION: Amyloid beta and tau pathology are the hallmarks of sporadic Alzheimer's disease (AD) and autosomal dominant AD (ADAD). However, Lewy body pathology (LBP) is found in ≈ 50% of AD and ADAD brains. METHODS: Using an α-synuclein seed amplification assay (SAA) in cerebrospinal fluid (CSF) from asymptomatic (n = 26) and symptomatic (n = 27) ADAD mutation carriers, including 12 with known
Semiconductor technology constantly advances, enabling integrated circuits (ICs) with increasingly numerous, faster, and smaller transistors. While this progress offers many benefits, it also presents new challenges, such as tighter margins, wear-outs, and process variations. To effectively tackle these challenges, the conventional approach of using external test instruments during manufacturing t
Distributed multiple-input multiple-output (D-MIMO) is a promising technology for simultaneous communication and positioning. However, phase synchronization between multiple access points in D-MIMO is challenging and methods that function without the need for phase synchronization are highly desired. Therefore, we present a method for D-MIMO that performs direct positioning of a moving device base
Advanced cellular communication systems provide increased potential for opportunistic high-accuracy positioning. In this paper, long-term evolution (LTE) downlink signals from two commercial base stations (BS) are received by a massive antenna array mounted on a passenger vehicle. Multipath component (MPC) parameters, like delays and angle-of-arrival (AOA) are extracted from the received signals o
Local political leaders as well as international organizations have embraced participatory budgeting in response to problems of political exclusion and citizens’ dissatisfaction with representative democracy. This article provides a framework to highlight important aspects of the politics of participation. The framework allows scholars to explore how factors external to spaces of participation intLocal political leaders as well as international organizations have embraced participatory budgeting in response to problems of political exclusion and citizens’ dissatisfaction with representative democracy. This article provides a framework to highlight important aspects of the politics of participation. The framework allows scholars to explore how factors external to spaces of participation int
Background: Weight gain and hypertension are well known adverse effects of treatment with high-dose glucocorticoids. Objective: To evaluate the effects of 2 years of low-dose glucocorticoid treatment in rheumatoid arthritis (RA). Design: Pooled analysis of 5 randomized controlled trials with 2-year interventions allowing concomitant treatment with disease-modifying antirheumatic drugs. Setting: 12
OBJECTIVE: To summarize the effectiveness of management strategies and rehabilitation approaches for knee joint structural and molecular biomarker outcomes following anterior cruciate ligament (ACL) and/or meniscal tear. DESIGN: Intervention systematic review. LITERATURE SEARCH: We searched the MEDLINE, Embase, CINAHL, CENTRAL, and SPORTDiscus databases from their inception up to November 3, 2021.
Use of static program analysis tools can be highly beneficial in software development, but usage is hindered by usability issues. One method to better understand these issues is to gather user feedback, but it is challenging to get developers to invest effort in giving user feedback.In this paper, we investigate whether gamification can increase user engagement in feedback collection on static ana
Critical reflection and self-reflection are two interrelated abilities universally perceived as fundamental for teachers’ professional practice. In European policy documents, these are also linked to the goal of building and consolidating education for democracy (Lenz et al., 2021, p. 9). Moreover, in the Swedish Higher Education Ordinance, they are mentioned in the second competence-and-skills ou
This paper proposes an alternative semi-analytical Fourier modal method adapted for general periodic anisotropic gratings made of dielectrics with moderate to low index profiles corresponding to materials ranging from conventional dielectric 3D printing materials to ceramic materials. The proposed method is closely related to classical Rigorous Coupled-Wave Analysis built on scattering matrices, h
Background: To support care after discharge following surgery for anorectal malformations (ARM) and Hirschsprung's disease (HD), an eHealth device was invented, offering families bilateral communication through chat, photo, questionaries and video. Aim: To explore the impact of eHealth on postoperative patterns of expert consultation, complications and treatment after discharge following surgery f
We report on local nowcasting (short-term forecasting) of coronavirus disease (COVID-19) hospitalizations based on syndromic (symptom) data recorded in regular healthcare routines in Östergötland County (population ≈465,000), Sweden, early in the pandemic, when broad laboratory testing was unavailable. Daily nowcasts were supplied to the local healthcare management based on analyses of the time la
Sustainability footprints are caused by semiconductor malfunctioning; production challenges (low yield) and customer returns (wear-out). We work with standards, techniques, and methods to quickly and accurately pin-point and mitigate malfunctioning aiming at graceful degradation to prolong operational lifetime.
Background: Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson’s disease (PD). Opicapone (OPC) is a third-generation, once-daily catechol-O-methyltransferase inhibitor shown to be generally well tolerated and efficacious in reducing OFF-time in two pivotal trials in patients with PD and end-of-dose motor fluctuations. The OpiCapone Effect on motor fluctuations
References to Jews and to matters included in Jewish discourse are commonplace in US popular culture in general and in US-produced hip-hop lyrics in particular. This article deals with the latter, and aims to analyse how Jews are represented there. It is suggested here that 1. these representations are rendered comprehensible by analysing them in the light of the term coined by Zygmunt Bauman: all
