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Introduction: Different strategies in prophylaxis for haemophilia among countries may affect long-term outcome. Aim: The aim of this study is to compare joint health in persons with severe haemophilia (PwSH) between Sweden and Greece, based on different approaches on prophylaxis initiation and management. Methods: Data were extracted from the PedNet Registry, which collects patient data prospectiv
BACKGROUND: The global prevalence of dementia is rapidly expanding and is expected to triple by 2050. Approximately 45 % of dementia cases are estimated to be attributable to potentially modifiable risk factors. Identifying how these factors contribute to specific brain pathologies may improve strategies to reduce dementia incidence.OBJECTIVES, DESIGN, SETTING: The aim of this study was to identif
This work investigates lightweight personalisation of micro-electro-mechanical systems (MEMS)-based wearables using a public padel database as a case study. We compare a centralised CNN model, single-user models and two fine-tuning schemes (full and last-layer) on wrist-worn IMU data from 23 players and 13 stroke classes. Personalised models with data augmentation achieve weighted F1-scores above
Vision impairment increases risks such as social isolation, mobility challenges, and falls. Wearable Augmented Reality (AR) devices with Artificial Intelligence (AI) can enhance sensory perception by enabling real-time recognition of obstacles, assisting visually impaired individuals during street navigation, aiming to reduce the risk of falls. In this paper, we propose a Federated Learning (FL) f
ImportanceGuidelines for temperature control following out-of-hospital cardiac arrest (OHCA) are based on trials with end points of 180 days or fewer.ObjectivesTo investigate if targeted hypothermia, compared with targeted normothermia with early treatment of fever, affects functional outcome focusing on societal participation or cognitive functioning at 24 months in initially comatose OHCA survivImportanceGuidelines for temperature control following out-of-hospital cardiac arrest (OHCA) are based on trials with end points of 180 days or fewer.ObjectivesTo investigate if targeted hypothermia, compared with targeted normothermia with early treatment of fever, affects functional outcome focusing on societal participation or cognitive functioning at 24 months in initially comatose OHCA surviv
Salivary amylase initiates the digestion of starch and it has been hypothesized that salivary amylase may play a role in the development of insulin resistance and type 2 diabetes. The aim was to examine the interaction between copy number variation in the salivary amylase gene AMY1 and starch intake. We studied 3,624 adults without diabetes or elevated blood glucose in the Malmö Diet Cancer cohort
Nitrogen (N) fertilization in forests has the potential to increase tree growth and carbon (C) sequestration, but it also means a risk of N leaching. Dynamic models can, if the important processes are well described, play an important role in assessing benefits and risks of nitrogen fertili-zation. The aim of this study was to test if the ForSAFE model is able to simulate correctly the effects of
Alternative reproductive tactics (ARTs) have provided valuable insights into how sexual selection and life history trade-offs can lead to variation within a sex. However, the possibility that tactics may constrain evolution through intralocus tactical conflict (IATC) is rarely considered. In addition, when IATC has been considered, the focus has often been on the genetic correlations between the A
In a learning situation, feedback is of great importance in order to help a student to correct a possible misconception. However, previous research shows that many students tend to avoid feedback regarding failures, including critical constructive feedback (CCF) that is intended to support and guide them. This is especially true for lower-achieving students, who might perceive feedback as an ego-t
Background: Personal recovery is associated with many significant health-related factors, but studies exploring associations between activity factors and personal recovery among service users are scarce. The aims of this study were hence to; 1) investigate if various aspects of activity may mediate change in recovery while also acknowledging clinical, sociodemographic and well-being factors; 2) ex
In October 2017, the EU Commission announced a consultation on supplementary protection certificates (SPCs) and research exemptions, including Bolar-type provisions. The consultation will provide valuable input for the Commission when preparing an evaluation of the current EU legislation, and any future policy proposals on SPCs and patent exemptions, including the assessment of the impact of diffe
Fundamental studies on combustion in laminar, nonpremixed flames are often carried out using conserved scalar quantities. These conserved scalar quantities, represented here by mixture fraction, E, are used as independent variables in activation-energy asymptotic analysis and in rate-ratio asymptotic analysis. These analyses are carried out in the asymptotic limit of large Damköhler number, with c
Sexual conflict and its evolutionary consequences are understudied in plants, but the theory of sexual conflict may help explain how selection generates and maintains variability. Here, we investigated selection on pollen and pistil traits when pollen arrives sequentially to partially receptive pistils in relation to pollen competition and a sexual conflict over timing of stigma receptivity in the
This paper presents measurements of W±Z production in pp collisions at a center-of-mass energy of 8 TeV. The gauge bosons are reconstructed using their leptonic decay modes into electrons and muons. The data were collected in 2012 by the ATLAS experiment at the Large Hadron Collider and correspond to an integrated luminosity of 20.3 fb-1. The measured inclusive cross section in the detector fiduci
This paper presents the extended results of measurements of W±W±jj production and limits on anomalous quartic gauge couplings using 20.3 fb-1 of proton-proton collision data at s=8 TeV recorded by the ATLAS detector at the Large Hadron Collider. Events with two leptons (e or μ) with the same electric charge and at least two jets are analyzed. Production cross sections are determined in two fiducia
Compound action potentials of both myelinated (A) and non-myelinated (C) fibres in the common peroneal nerve of rabbits were studied during and after acute, graded compression of the nerve at 200 or 400 mmHg applied for 2 h or during ischaemia created by nitrogen inhalation or aortic occlusion. Compression of the nerve at 200 mmHg blocked the AI component (large myelinated fibres) after about 23 m
Background: Rheumatoid arthritis (RA) is a chronic, inflammatory rheumatic disease with the potential to induce significant disability. Patients with RA are at increased risk of cardiovascular diseases (CVD). Smokers with RA tend to experience more pain and fatigue, higher disease activity, more erosive joint destruction and a lower health-related quality of life (HR-QoL) than non-smokers. It rema
In the Mediterranean area, the 4.2 ka BP event is recorded with contrasting expressions between regions. In the southern Alps, the high-altitude Lake Petit (Mercantour Massif, France; 2200 m a.s.l.) offers pollen and diatom-rich sediments covering the last 4800 years. A multi-proxy analysis recently revealed a detrital pulse around 4200 cal
Despite the likely increasing co-occurrence of drought and heat stress, not least in equatorial regions, due to climate change, little is known about the combinational effect of these stresses on rice productivity and quality. This study evaluated the impact of simultaneous drought and temperature stress on growth, grain yield, and quality characteristics of seven rice cultivars from Rwanda, grown
