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Biomechanical factors associated with the development of tibiofemoral knee osteoarthritis : Protocol for a systematic review and meta-analysis

Introduction: Altered biomechanics, increased joint loading and tissue damage, might be related in a vicious cycle within the development of knee osteoarthritis (KOA). We have defined biomechanical factors as joint-related factors that interact with the forces, moments and kinematics in and around a synovial joint. Although a number of studies and systematic reviews have been performed to assess t

AsIII Selectively Induces a Disorder-to-Order Transition in the Metalloid Binding Region of the AfArsR Protein

Arsenic is highly toxic and a significant threat to human health, but certain bacteria have developed defense mechanisms initiated by AsIII binding to AsIII-sensing proteins of the ArsR family. The transcriptional regulator AfArsR responds to AsIII and SbIII by coordinating the metalloids with three cysteines, located in a short sequence of the same monomer chain. Here, we characterize the binding

Hydrophobic homopolymers of native α-L-amino acids at the air-water interface : A study by circular dichroism spectroscopy, atomic force microscopy, and surface balance experiments

Films of poly-L-leucine, poly-L-valine, and poly-L-isoleucine have been studied at the air-water interface by surface balance experiments. In addition, Langmuir-Blodgett (LB) films of these polypeptides deposited onto quartz and mica have been studied by circular dichroism (CD) spectroscopy and atomic force microscopy (AFM) to elucidate the effects of polypeptide conformation and spreading agent (

Young male mating success is associated with sperm number but not with male sex pheromone titres

Background: Intraspecific communication is of crucial importance throughout the animal kingdom and may involve a combination of visual, gustatory, olfactory and acoustic cues. Variation in male sex pheromone amount and composition may convey important information to female conspecifics, for instance on species identity or age. However, whether increased male pheromone titres are associated with fi

Geometry of plastic deformation in metals as piecewise isometric transformations

Deformation mechanisms of crystalline solids has been the subject of research for more than two centuries. The theory of dislocations dominates modern views but still has significant gaps demanding the introduction of additional concepts for the coherent quantitative description of physical phenomena. In this work, we propose a coherent geometric description of motion and deformation in crystallin

Remembering Classical Scandinavia in Britain, 1760–1830

Remembering Classical Scandinavia in Britain, 1760–1830 explores the use of Scandinavian themes in British culture in the decades around 1800. It offers new paradigms for how cultural texts engage with the classical Scandinavian past, historiographically and thematically. The classical Scandinavian past was the subject of intense interest during the period but often also coupled with a sense that

How and Why Freight Trains Deviate from the Timetable : Evidence from Sweden

European infrastructure managers (IMs) create annual timetables for trains that will run during a year. Freight trains in Sweden often deviate from this by being added, cancelled, delayed or early, resulting in increased costs for IMs and railway undertakings (RUs). We investigate the frequency of and causes for these deviations, using one year of operational data for 48,000 trains, and 15 stakeho

Understanding the characteristics of non-equilibrium alternating current gliding arc discharge in a variety of gas mixtures (air, N2, Ar, Ar/O2, and Ar/CH4) at elevated pressures (1-5 atm)

This work aims at clarifying the fundamental mechanisms of non-equilibrium alternating current gliding arc discharge (GAD) by investigating effects of gas compositions and pressures on the GAD characteristics with electrical and optical methods. Interestingly, the glow-to-spark transition was found by adding O2 or CH4 into the argon or modulating the power supply. This transition occurs attributed

On the sign recovery by least absolute shrinkage and selection operator, thresholded least absolute shrinkage and selection operator, and thresholded basis pursuit denoising

Basis pursuit (BP), basis pursuit deNoising (BPDN), and least absolute shrinkage and selection operator (LASSO) are popular methods for identifying important predictors in the high-dimensional linear regression model (Formula presented.). By definition, when (Formula presented.), BP uniquely recovers (Formula presented.) when (Formula presented.) and (Formula presented.) implies (Formula presented

Exploring infants' cooperative participation in early social routines.

Cooperation and joint actions are often investigated in terms of how individuals explicitly coordinate their plans and intentions to achieve a shared goal. However, goals may also be achieved without prior arrangements, when, for instance, an individual takes part in someone else’s action without an explicit agreement, helping that action to be performed. Participating in social interaction may be

Commonly overlooked factors in biocompatibility studies of neural implants

Biocompatibility of cutting-edge neural implants, surgical tools and techniques, and therapeutic technologies is a challenging concept that can be easily misjudged. For example, neural interfaces are routinely gauged on how effectively they determine active neurons near their recording sites. Tissue integration and toxicity of neural interfaces are frequently assessed histologically in animal mode

Sorption of 71 Pharmaceuticals to Powder Activated Carbon for Improved Wastewater Treatment

In this study, sorption distribution coefficients were determined for 71 pharmaceuticals, aiming to describe their sorption behavior to powder activated carbon (PAC). The data are expected to be applied when designing and upgrading wastewater treatment plants (WWTP) for improved removal of pharmaceuticals by applying sorption to PAC as an additional removal technique. Sorption isotherms were deter

Region work – Institutional activism and the implementation of regional reform

In 2016, the Norwegian government initiated an extensive reform of the regional scale, eventually reducing the number of political-administrative counties from nineteen to eleven through mergers. The territorial and institutional changes that followed can be understood as a partial regional (de/re)institutionalisation process, in which the political and administrative boundaries of the merged coun

Set in Motion : Paradoxical narratives of becoming Swedish digital media influencers

This article analyzes how Swedish digital media influencers make sense of their careers in print media interviews and autobiographical books. I explore how influencers use meta-phors involving motion, speed and acceleration to describe, explain and legitimate the various circumstances and phases of their career development, and how these metaphors may be viewed in the wider context of social accel