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Aim: To explore the association between the coagulation protein fibrinogen and the fibrinolytic biomarker plasminogen activator inhibitor-1 ( PAI- 1) and the long- term mortality after coronary artery bypass grafting ( CABG). Patients and Methods: In 729 patients undergoing CABG at Sahlgrenska University Hospital, a blood sample for fibrinogen and PAI-1 was collected prior to the procedure. Patien

We present and test two methods to use quantum chemical calculations to improve standard protein structure refinement by molecular dynamics simulations restrained to experimental NMR data. In the first, we replace the molecular mechanics force field ( employed in standard refinement to supplement experimental data) for a site of interest by quantum chemical calculations. This way, we obtain an acc

Pan-African high-grade metamorphism in the Proterozoic Damara orogen (Namibia) led to formation of garnet-bearing leucosomes in potassic meta-igneous gneisses producing a meta-igneous migmatite. In addition, the migmatite (gneiss (mesosome) plus leucosome) was intruded by small-scale leucogranitic melts with a high amount of accumulated biotite and garnet. U-Pb zircon ages obtained on the mesosome

We here present new insights of properties of real-life interference graphs emerging in register allocation. These new insights imply good hopes for a possibility of improving the coloring approach towards optimal solutions. The conclusions axe based on measurements of nearly 28,000 real instances of such interference graphs. All the instances explored are determined to possess the so-called 1-per

The aim of this article is to examine conceptually and empirically how innovative firms combine knowledge (1) provided by different sources, (2) accessed at different spatial scales and (3) acquired through different channels. We add to the conceptual debate by contrasting and synthesising the perspectives offered on these issues by four key concepts, namely the local buzz and global pipelines arg

Abstract Patients' satisfaction is an important outcome measure in reconstructive surgery and quality assurance is today central in the clinical practice. The aim of this study was to evaluate the patients' satisfaction with the process and final result after reconstruction for congenital microtia. A questionnaire was designed and sent to 78 patients who had undergone unilateral ear reconstruction

To control flight, insects rely on the pattern of visual motion generated on the retina as they move through the environment. When light levels fall, vision becomes less reliable and flight control thus becomes more challenging. Here, we investigated the effect of light intensity on flight control by filming the trajectories of free-flying bumblebees (Bombus terrestris, Linnaeus, 1758) in an exper

Popular Abstract in Swedish Rätten till domstolsprövning är en grundläggande rättighet som förekommer i alla demokratiska stater. Utgångspunkten är att alla har rätt att få sina tvister prövade av en domstol i ett förfarande som uppfyller vissa kvaliteter, en rättvis rättegång, och att staten har ett ansvar att tillhandahålla förutsättningar för sådana tvistlösningsförfaranden inför domstol. DäremOne of the most fundamental rights in any democratic state is the right of access to court. Every individual shall have the right to bring legal disputes before a court, in a proceeding with specifically defined characteristics, a fair trial, and the state is responsible for supplying the conditions and prerequisites to carry out this dispute resolution process in a court of law. However, this rig

We propose a method for statically analyzing components that can be part of Android applications and which have not been very well analyzed so far, namely native libraries. As of now, third-party native code can be seen as a black box that can be fed input parameters from the Dalvik bytecode context, and output parameters can be returned back to the bytecode context. However, the native code can s

The historical role of European farming in southern and central Africa is a delicate matter that has received a great deal of attention among scholars over the years. Going through this vast literature a striking consensus emerges: success or failure of European farming in southern Africa was to a large extent depending on their access and control over labour. These propositions have so far never

Being able to orient in the vicinity of the home and independently go shopping or visiting a friend can become increasingly difficult when a person suffers from memory decline. The adaption of traditional navigation apps based on satellite positioning could provide an aid, but there are several questions to investigate related to the design and function of such an app. These questions include how

The intention of this study is to question the supposed self-evident connection between sickness and sin in the individual complaint psalms. On the basis of a careful analysis of the psalms which contain the three motifs divine absence, divine wrath, and man’s guilt, the author problematizes this aspect of the exegetical literature’s widespread interpretation of the theological dimension of illnes

Recent observations by the Goddard High-Resolution Spectrograph on the Rubble Space Telescope have dramatically improved our knowledge of the abundance of the heaviest elements in Mercury-Manganese (HgMn) stars (c.f. Leckrone et al. 1992 and Wahlgren et al. 1995). Explaining the observed abundance and isotope anomalies requires improved calculations of radiatively driven diffusion. We briefly revi