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Effects of ultrasound contrast agents on Doppler tissue velocity estimation

The combination of Doppler tissue imaging and myocardial contrast echocardiography has the potential to provide information about motion and perfusion of the myocardium in a single examination. The purpose of this study was to establish how the presence of ultrasound contrast agent (UCA) affects measurements of Doppler tissue velocities in vivo and in vitro. We performed echocardiography in 12 pat

The influence of vigilance on intraguild predation

Theoretical work on intraguild predation suggests that if a top predator and an intermediate predator share prey, the system will be stable only if the intermediate predator is better at exploiting the prey, and the top predator gains significantly from consuming the intermediate predator. In mammalian carnivore systems, however, there are examples of top predator species that attack intermediate

Role of p190RhoGAP in beta(2) integrin regulation of RhoA in human neutrophils

We found that engagement of beta (2) integrins on human neutrophils induced activation of RhoA, as indicated by the increased ratio of GTP:GTP + GDP recovered on RhoA and translocation of RhoA to a membrane fraction. The clustering of beta (2) integrins also induced a time-dependent increase in GDP bound to RhoA, which correlated with beta (2) integrin-induced activation of p190RhoGAP. The activat

Studies of two Yersinia proteins: YopJ, an inhibitor of inflammatory responses, and YpkA, a RhoA/Rac-binding kinase

Eukaryotic cells possess sensitive systems for the detection of microbes and microbial-derived products. Bacteria-eukaryotic cells contact triggers several signaling pathways, most of which are dependent on protein-protein interactions followed by phosphorylation, leading to activation of defense mechanisms. Yersinia bacteria have evolved different strategies to interfere with eukaryotic host defe

Advanced resource connector (ARC) - the grid middleware of the NorduGrid

Summary form only given. The advanced resource connector (ARC), or the NorduGrid middleware, is an open source software solution enabling production quality computational and data grids. Since the first release (May 2002), the middleware is deployed and being used in production environments. Emphasis is put on scalability, stability, reliability and performance of the middleware. A growing number

Experimental Bladder Reconstruction

Reduced urinary bladder capacity is a clinically significant problem. The surgical methods that have been available to treat this, such as urinary diversion or surgically augmenting the bladder by incorporation of intestinal segments, all have serious drawbacks. There is a need to understand how the smooth muscle of the intestine and bladder can interact when brought into close contact surgically,

Synchrotron X-ray Scattering and Monte Carlo Simulations of Structure and Forces in Silicate Nanoplatelet Dispersions

Popular Abstract in Swedish Lera-vatten-systemet finns i stort sett överallt i vår omgivning. Syftet med denna avhandling är att identifiera och undersöka egenskaper hos leror som är av betydelse för deras inbördes växelverkan. Leror är sammansatta av två eller tre molekylära lager och får därför en relativt komplex fördelning av elektrostatiska laddningar. Denna fördelning förändras med olika betClays are the world’s most widely used natural material, however, little is known regarding the microstructure as well as the forces involved in clay-water interactions, and their influence on the swelling properties. The utilization of clay platelets is nowadays a key in a number of biological and industrial applications e.g. nuclear waste management. Bentonites from different natural sources an

Improvement of Texture by Modifying Processing Conditions

Fruit and vegetable processors, faced with the challenge of gaining and maintaining a healthy position in the competitive fruit and vegetable sector, are optimising traditional processes towards product quality. Using frozen potatoes as a case study, the aim of this study was to evaluate the potential of improving the texture of potatoes by modifying the processing conditions. The texture of proce

Cystatin C, a marker for successful aging and glomerular filtration rate, is not influenced by inflammation.

Abstract Background. The plasma level of cystatin C is a better marker than plasma creatinine for successful aging. It has been assumed that the advantage of cystatin C is not only due to it being a better marker for glomerular filtration rate (GFR) than creatinine, but also because an inflammatory state of a patient induces a raised cystatin C level. However, the observations of an association be

Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension: obesity and difficult to treat arterial hypertension.

Obese patients are prone to arterial hypertension, require more antihypertensive medications, and have an increased risk of treatment-resistant arterial hypertension. Obesity-induced neurohumoral activation appears to be involved. The association between obesity and hypertension shows large inter-individual variability, likely through genetic mechanisms. Obesity affects overall cardiovascular and

Modified Ritgen's maneuver for anal sphincter injury at delivery: a randomized controlled trial.

OBJECTIVE: To investigate whether Ritgen's maneuver decreases the risk of third- to fourth-degree perineal tears compared with simple perineal support. METHODS: A total of 1,623 nulliparous women in term labor, singleton pregnancy, and cephalic presentation were randomly assigned to Ritgen's maneuver or standard care. Ritgen's maneuver denotes extracting the fetal head, using one hand to pull the

Development and implementation of a standardized care plan for carotid endarterectomy.

Carotid endarterectomy (CEA) is a standardized surgical procedure and is the third most common vascular surgical procedure in Sweden. To improve the quality of pre- and postoperative care for patients undergoing elective CEA, a standardized care plan (SCP) was developed and implemented during Spring of 2007 at a vascular clinic in Sweden. In order to spread light on obstacles and possibilities in

Six-week follow-up after HIV-1 exposure: a position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy.

In 2014 the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy (RAV) conducted a review and analysis of the state of knowledge on the duration of follow-up after exposure to human immunodeficiency virus (HIV). Up until then a follow-up of 12 weeks after exposure had been recommended, but improved tests and new information on early diagnosis motivated a re-evaluati

Making B2B Sales Interactions Valuable - A Social and Symbolic Perspective

Salespeople’s work has always been regarded a crucial contributor to businesses’ value creation by researchers and practitioners alike. As tangible products are not at the core of interactions between salesperson and customer in the context of services-based or non-standardized markets, sales’ role is assigned greater influence in the understanding, creating and delivering of customer value. Under

Reduction in Secondary Losses in Turbine Cascade Using Contoured Boundary Layer Fence

Present work deals with reducing secondary losses in turbine cascade by using boundary layer fences in two ways. Firstly, to reduce the strength of vortex which is incident at the leading edge of airfoil and hence reduce the strength of horse shoe vortex, and secondly, to reduce the pressure gradient between the pressure side and the suction side in the flow passage region between airfoils. In pre

NMR Self-Diffusion Studies of Surfactant and Polymer Systems. Methodology and Applications

The main focus of this thesis has been to explore how the PFG NMR technique for diffusion measurements can be used to obtain useful information from various systems. The investigated systems have one thing in common; they belong to the general field of surface and colloid chemistry. The thesis is divided in two parts: one section is a summary and the other section contains four publications from

Language and Vision. Using visual information in real-world language situations

Popular Abstract in Swedish Denna avhandling undersöker hur vi använder visuell kontextinformation i samtal. Alla modeller över språkprocessning och kommunikation är ense om att visuell kontextinformation har en positiv nettoeffekt på förståelse och kommunikation. Trots detta är det inte klart genom vilka mekanismer denna kontextinformation verkar, eller om dessa mekanismer fungerar i situationer This dissertation is about the role of visual context information in communication. All accounts of language processing and communication agree that visual context is beneficial for understanding. Despite this, it is not clear through which mechanisms visual context works and whether these mechanisms also work in communication outside the lab setting. This dissertation aims to provide answers to t