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Multivalent ions and biomolecules : Attempting a comprehensive perspective

Ions are ubiquitous in nature. They play a key role for many biological processes on the molecular scale, from molecular interactions, to mechanical properties, to folding, to self-organisation and assembly, to reaction equilibria, to signalling, to energy and material transport, to recognition etc. Going beyond monovalent ions to multivalent ions, the effects of the ions are frequently not only s

Social deprivation and urbanity as the elephant in the room

Social deprivation and marginalization in urban areas are hardships that are not necessarily limited to developing countries. Around 80 million Europeans today live in conditions that fall within the definition of poverty. However, certain areas are more prone to affliction than others. Such estates usually consist of concrete slab high-rise buildings and are often characterized by high levels of

Fluorine in the Solar Neighborhood : The Need for Several Cosmic Sources

The cosmic origin of fluorine is still not well constrained. Several nucleosynthetic channels at different phases of stellar evolution have been suggested, but these must be constrained by observations. For this, the fluorine abundance trend with metallicity spanning a wide range is required. Our aim is to determine stellar abundances of fluorine for. We determine the abundances from HF lines in i

Drosophila melanogaster dihydroorotate dehydrogenase : the N-terminus is important for biological function in vivo but not for catalytic properties in vitro

Dihydroorotate dehydrogenase (DHODH, EC 1.3.99.11), the fourth enzyme of pyrimidine de novo synthesis, is an integral flavoprotein of the inner mitchondrial membrane and is functionally connected to the respiratory chain. Here, experiments have been directed toward determining the roles of the N-terminal sequence motifs both in enzymatic properties of insect DHODH produced in vitro and the in vivo

Sex pheromone biosynthesis of (E, E)-8,10-dodecadienol in codling moth Cydia pomonella involves E9 desaturation

Sex pheromone biosynthesis in the codling moth Cydia pomonella (Lepidoptera; Tortricidae) was studied by topical application of deuterated fatty acids in DMSO to pheromone glands. The incorporation of deuterium label into fatty acids and alcohols in the pheromone gland was monitored by gas chromatography with flame ionization detection and mass spectrometry in the selected ion monitoring mode. Dod

Finally, inkjet-printed metal halide perovskite LEDs-utilizing seed crystal templating of salty PEDOT:PSS

Solution-processable metal halide perovskites are increasingly implemented in perovskite-based light-emitting diodes (PeLEDs). Especially green PeLEDs based on methylammonium lead bromide (MAPbBr3) composites exhibit impressive optoelectronic properties, while allowing processing by low-cost and upscalable printing methods. In this study, we have investigated the influence of potassium chloride (K

Unlocking successful sustainability : innovative communication strategies for science based policy

Environmental policy should be made up of scientific evidence. This thesis paper supports science based policy and its formulation through innovative communication strategies. It is important to be innovative in communicating science when dealing with the policy community as there could be confrontations owing to the nature of relation between science and policy. This is where the professional env

Numerical Investigations of a Partitioned FSI Algorithm for Tetra Pak's Filling Tube

Numerical simulations of fluid-structure interaction of a water-filled tube with a free surface are conducted using an implicit partitioned coupling scheme. Abaqus and STAR-CCM+ are used for the solid- and fluid domains respectively. This application has stability issues, with the most severe turning out to be the added mass effect. Rayleigh β damping and grid flux under-relaxation has been used t

Transfer Pricing Treatment of Transactions with Hard-to-Value Intangibles: Is BEPS Action 8 Based on the Arm’s Length Principle?

This master’s thesis analyses BEPS Action 8 recommendations in relation to transactions with hard-to-value intangibles. OECD has developed them with a view to ensure that transfer pricing outcomes of transactions with hard-to-value intangibles are aligned with value creation. The author discusses whether the proposed measure is in line with the arm’s length principle – the internationally recogniz

Patient-specific blood vessel modeling on data from MR scans of children with congenital heart disease

En procent av alla barn i Sverige har ett medfött hjärtfel som ofta kräver en kirurgisk korrigering. De senaste femtio åren har vi sett en kraftig ökning i användandet av evidensbaserad medicin för att upptäcka och behandla medfödda hjärtfel. Detta har varit mycket lyckat men behandlingar är inte anpassade efter individuella behov. På grund av detta har patientspecifik medicin tillkommit som en föOne percent of children have a congenital heart disease, often requiring surgical corrections. The last fifty years have seen a sharp increase in the use of evidence based medicine to identify and treat congenital heart diseases. This has been highly successful but treatments are not customized for individual patients. Because of this, patient specific medicine has emerged as an improvement where

What comes first: the market or the product? Strategic orientations among start-ups in the Øresund Region

Market orientation and product orientation propose opposite approaches towards innovation and, thus, value-creation. This paper investigates the market-product orientation debate in the context of entrepreneurial start-ups. By studying strategic orientation from the perspective of start-up entrepreneurs, the research contributes to orientation theory, which has largely concentrated on processes fo

Grön offentlig entreprenadupphandling - I EU, Sverige och Lunds kommun

EU:s regelverk om offentlig upphandling uppdaterades 2014 och snart kommer uppdateringen i den svenska lagtexten. Det blir nu ännu tydligare att det är tillåtet att ställa miljökrav vid offentlig upphandling. Det är en vanlig uppfattning att det inte går att upphandla varor, tjänster och byggnadsverk med bättre miljöprestanda eftersom att de traditionellt sett inte kan konkurrera med kriteriet ”This is a master’s thesis about green public procurement (GPP) in the construction sector, based on a legal dogmathic study and a case study. The legal dogmathic part focused on both EU-legislation and on Swedish legislation. The case study was performed on the municipal of Lund to understand how a small authority works with GPP. The study of EU-legislation shows that the possibility to request b

Understanding the ERP system use in budgeting

This paper investigates the enterprise resource planning (ERP) system use in budgeting in order to explain how and why ERP system are used or not used in budgeting practices. Budgeting is considered as a social phenomenon which requires flexibility for decision-making and integration for management controls. The analysis at the activity levels, guided by the concept of ‘conflict’ in structuration

Interdependence in supply chains and projects in construction

Purpose – The aim of this paper is to inquire into the management of construction supply chains by directing attention toward the different types of interdependencies that exist in such chains and in construction projects. Design/methodology/approach – The paper is developed as part of two ongoing research projects on supply chain management (SCM) in construction. A case study approach is used fo

Government Procurment in the EPAs

The trade relationship between the EU and the ACP countries are currently being renegotiated under the framework of European Partnership Agreements. These EPAs are not only concerned with traditional market access commitments but are also targeting the ‘Singapore issues’ and especially the area of government procurement. The reason for this is found in the economics of trade theory that illustrate

CYP2D6 UM phenotype is not related to suicide attempts in depressive patients in secondary psychiatric care

Introduction: The hepatic cytochrome P450 system includes the polymorphic CYP2D6 gene. CYP2D6 ultra rapid metabolizers (UMs) were 10-fold more common in suicide victims than in the general population in a previous study. The aim of this study was to investigate if the occurrence of the CYP2D6 UM genotype differs between subjects with and without previous suicide attempt in patients treated for dep