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The utility of histology in assessing the cause of death in medico-legal autopsies in selected trauma deaths : Suspension-, immersion-, fire-, and traffic-related

The goal of a medico-legal autopsy is primarily to determine the cause and manner of death. To this end, the pathologist often uses auxiliary analyses, including histology. However, the utility of routine histology in all medico-legal autopsies is unknown. Earlier studies on the utility of routine histology have shown inconsistent effects, with some studies recommending it and others rejecting it.

Targeting of bone morphogenetic protein complexes to heparin/heparan sulfate glycosaminoglycans in bioactive conformation

Bone morphogenetic proteins (BMP) are powerful regulators of cellular processes such as proliferation, differentiation, and apoptosis. However, the specific molecular requirements controlling the bioavailability of BMPs in the extracellular matrix (ECM) are not yet fully understood. Our previous work showed that BMPs are targeted to the ECM as growth factor-prodomain (GF-PD) complexes (CPLXs) via

Molecular co-operation between protein PAM and streptokinase for plasmin acquisition by Streptococcus pyogenes.

Bacterial surface-associated plasmin formation is believed to contribute to invasion, although the underlying molecular mechanisms are poorly understood. To define the components necessary for plasmin generation on group A streptococci we used strain AP53 which exposes an M-like protein ("PAM") that contains a plasminogen-binding sequence with two 13-amino acid residues long tandem repeats (a1 and

Pricing Capability and Its Strategic Dimensions

Popular Abstract in Swedish Iden att prissättning är något mycket viktigt för företag stöds av en lång rad publikationer som ger råd kring hur företag bör sätta pris för att maximera sin långsiktiga lönsamhet. Detta indikerar att prissättning, eller företags prissättningsförmåga, borde utgöra ett viktigt område inom strategiforskning som har som sin primära målsättning att utveckla vetenskapliga fThe notion of pricing as being of vital importance to firms is supported by a long line of publications that outline recommendations on how price should be managed in order to maximize long-term profits. This implies that pricing, or firm level pricing capability, should constitute an important area of research in the field of strategic management, a field which has as its prime objective to devel

Önskat eller oönskat? Trädgårdens växter mellan natur och kultur

In the home garden, people inevitably interact with a multitude of non-human actors, including plants. Home gardeners get involved with, and affect, the growth, life and death of other individuals through activities such as weeding and pruning. In this article, the authors discuss people’’s everyday interactions with ‘‘nature’’ in their own gardens, with a specific focus on plants. Despite their r

Safety at cycle crossings : The relationship between motor vehicle drivers’ yielding behaviour and cyclists’ traffic safety

With a high share of motor vehicles yielding to crossing cyclists, cyclists’ waiting time decreases and their level of service increases. The main aim of this paper is to study how this propensity to yield is connected to the traffic safety situation for cyclists at cycle crossings in a Swedish context. In a previous study, motor vehicle drivers’ yielding behaviour was studied at 65 cycle crossing

Disturbance Management in a DC Grid using a Hierarchical Control Structure

DC grids will play a key role in the future, interconnecting generation and load centers as well as energy markets. Large multi-terminal VSC-HVDC systems of high capacity will require automated coordination for several operation scenarios especially when operating under disturbances. With this in mind, and considering the dynamics of a DC system, communication loss events are considered severe dis

Designing a social and assistive robot for seniors

Background: The development of social assistive robots is an approach with the intention of preventing and detecting falls among seniors. There is a need for a relatively low-cost mobile robot with an arm and a gripper which is small enough to navigate through private homes. Material and methods: User requirements of a social assistive robot were collected using workshops, a questionnaire and inte

Women’s Bigger Burden : Disparities in Outcomes of Large Scale Land Acquisition in Sierra Leone

Women farmers make up a majority of small-scale food producers in sub-Saharan Africa. Despite their important role in the food and livelihood security of their households and communities, women continue to face substantial challenges in their rights of and access to land resources in the region. In a number of countries such as Sierra Leone where large-scale land acquisition is ongoing, we posit t

Sensitization of Staphylococcus aureus to methicillin and other antibiotics in vitro and in vivo in the presence of HAMLET

HAMLET (human alpha-lactalbumin made lethal to tumor cells) is a protein-lipid complex from human milk with both tumoricidal and bactericidal activities. HAMLET exerts a rather specific bactericidal activity against some respiratory pathogens, with highest activity against Streptococcus pneumoniae, but lacks activity against most other bacterial pathogens, including Staphylococci. Still, ion trans

From charity to institutional development: Reflections on Newmont’s CSR strategies and conflict-avoidance in Ghana

In 2003 Newmont has signed an investment agreement with the government of Ghana that resulted in the inauguration in 2006 of the large, gold-producing project at Ahafo. The challenge for Newmont has been to resolve the initial conflict resulting from a land dispossession that brought communities close to famine and address the lingering tensions by working towards sustainable solutions. This artic

Long-term explant culture of rabbit flexor tendon : Effects of recombinant human insulin-like growth factor-I and serum on matrix metabolism

The effects of human recombinant insulin-like growth factor-I (rhIGF-I, 50 ng/ml) on matrix metabolism in the deep flexor tendon from the tendon sheath region of the rabbit were studied in explants cultured for 3 weeks. Tendon segments cultured in medium supplemented with fetal calf serum (FCS) exhibited proliferation of the superficial cell layers. Synthesis of proteoglycan and non-collagen prote

Studies of phase-change materials using ultrafast X-ray diffraction

This thesis is focused on the investigation of the ultrafast structural response of the phase change material (PCM) Ge$_2$Sb$_2$Te$_5$ following laser excitation. Phase change materials are a group of materials capable of rapid, non-volatile, switching between an amorphous and a crystalline phase. The two phases exhibit high optical and electrical contrast, meaning the optical reflectivity and the

Is release in the wild of an old female that has lived her life in captivity possible? Observations from a lynx breeding centre

The Iberian lynx was once recognized as the world’s most threatened felid, but due to the implementation of a conservation programme and the creation of captive breeding centres, its numbers have considerably increased. With the annual production of new individuals in these reproduction centres, as well as the inevitable aging of past breeders, a different problem emerged: the hoarding of non-repr

Due Diligence and Due Remedy? A Critical Evaluation of Human Rights Due Diligence in the UN Binding Treaty on Business and Human Rights: Lessons from Marikana and Comparative Case Studies.

The discourse on Business and Human Rights (BHR) has evolved substantially over the past two decades, particularly since the adoption of the UN Guiding Principles on Business and Human Rights (UNGPs) in 2011. While the UNGPs established the corporate responsibility to respect human rights through Human Rights Due Diligence (HRDD), their voluntary nature has resulted in fragmented implementation an