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Two groups of normal subjects were submitted to repeated automated static threshold perimetry. Perimetric results were strongly affected by the level of experience in some subjects; in the majority, however, the effect of experience was small. Initial field tests often showed high numbers of depressed points. Sensitivity increased with perimetric training, particularly between the first sessions.

Europe is building its Open Science Cloud; a set of robust and interoperable e-infrastructures with the capacity to provide data and computational solutions through cloud-based services. The development and sustainable operation of such e-infrastructures are at the forefront of European funding priorities. The research community, however, is still reluctant to engage at the scale required to signa

Information literacy and critical thinking skills are essential in the information age towards achieving academic success and being adequately skilled for lifelong learning. Academic libraries have an indispensable role to play in this regard. Collaboration between librarians and academics is important to ensure both effective information-literacy training and service provision to students and to

Cryptochromes are blue-light photoreceptor proteins, which provide input to circadian clocks. The cryptochrome from Drosophila melanogaster (DmCry) modulates the degradation of Timeless and itself. It is unclear how light absorption by the chromophore and the subsequent redox reactions trigger these events. Here, we use nano- to millisecond time-resolved x-ray solution scattering to reveal the lig

Human proinsulin (HPI) and C-peptide (HCP) were visualized by specific monoclonal antibodies (Mab's) in the conventional indirect immunofluorescent assay for ICA (islet cell cytoplasmic antibodies) on frozen sections of human pancreas. Two different Mab's, GS-9A8 (anti-HPI, mouse IgG1) and GN-ID4 (anti-HPI/HCP, rat IgG2A), showed intense islet cell cytoplasmic staining. In contrast to the anti-HPI

The effects of phlorizin on several parameters of β-cell function were studied with microdissected islets of obese-hyperglycemic mice. At a concentration of 10 mM, phlorizin significantly depressed insulin release, glucose transport, glucose oxidation, and the level of fructose 1,6-diphosphate, when tested in the presence of 10 mM glucose. Whereas 1 mM phlorizin inhibited glucose transport by abou

Cyclin-dependent kinase 1 (Cdk1) is an archetypical kinase and a central regulator that drives cells through G2 phase and mitosis. Knockouts of Cdk2, Cdk3, Cdk4, or Cdk6 have resulted in viable mice, but the in vivo functions of Cdk1 have not been fully explored in mammals. Here we have generated a conditional-knockout mouse model to study the functions of Cdk1 in vivo. Ablation of Cdk1 leads to a

The purpose of this study was to identify the reasons behind the employees noncompliant purchasing behavior at Company X. Another aim was to find the solutions to the reasons behind the non-compliant purchasing behavior to change that behavior. This study was carried out by following an abductive approach, where a qualitative case study research was conducted. The chosen case study method was a mu

An ambiguity characterises Swedish Sami policy. In some regards, Sweden is securing rights for the Sami and receiving praise from international organisations. However, Sweden is also criticised for not supporting Sami interests, as for instance regarding a ratification of the ILO convention No. 169. Thus, Swedish Sami policies have showed to support disparate ends; in some instances strengthening

Syftet med denna studie är att undersöka musiklärares erfarenheter med betygssättning och bedömning. I denna kvalitativa studie intervjuas sex undervisande musiklärare, med fokus på gymnasiekursen Ensemble med Körsång. Resultatet visar på att musiklärare uppfattar en problematik när det kommer till att likvärdigt tolka de nuvarande styrdokumenten på grund av att det i Lgy 11 inte uttrycks hur kuns

Since 2008, the European Union requires the candidate and neighbourhood countries to undertake reforms in the field of citizens’ rights, including protection of minorities in order to give their nationals access to the Schengen area for the short-term stays. However, within the visa liberalisation procedure, the European Union has demonstrated ambivalence in monitoring the implementation of these