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Methods. Linear regression was used to relate log-measured GFR (mGFR) to sex, race, diabetes, transplant, weight, various transformations of creatinine and age with and without interactions. Equations were developed in a pooled database of 10 studies [2/3 (N = 5504) for development and 1/3 (N = 2750) for internal validation], and final model selection occurred in 16 additional studies [external va

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Co-location alone is not sufficient to ensure efficient and effective interaction between economic agents. Also, institutions at multiple scales shape the behaviour of organizations and provide incentives for interaction. However, institutions, as well as the impact of institutions on economic agents, are not static, but rather change over time. In this paper we investigate this dynamic process: H

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In this study, numerical simulations are conducted to investigate the effects of bowed outlet guide vanes (OGVs) on endwall heat transfer and aerodynamic performance. Both on- and off-design conditions are studied. For bowed vanes, the bowed angle varies from 10 degrees to 40 degrees and the normalized bowed height ranges from 0.1 to 0.3. Results are included for Nusselt number distributions on th

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Predictability is a key function of law. When the application of law goes from being flexible to becoming unpredictable this key function is lost. This article shows how legal application can deviate from formal agreements and law, how legal predictability experiences a setback when other forces or values affect the decision making that is supposed to be strictly legally controlled. Non-legally ac

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Background and Purpose-In a genome-wide association study and subsequent case-control studies, the single-nucleotide polymorphism rs12425791 on chromosome 12p13 was reported to be associated with ischemic stroke, but this could not be validated in a recent well-powered study. We therefore investigated whether an association between ischemic stroke and rs12425791 could be detected in 3 different ca

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By the end of 2020, all EU member states need to ensure that all newly constructed buildings consume ` nearly zero' energy and that their energy needs are produced locally as much as possible and with renewable sources; a concept called nearly Zero Energy Buildings (ZEB). At the same time, more and more people live in cities, where the access to local renewable energy sources -wind and solar-is li

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Apolipoprotein A-I (apoA-I) is the main protein of high-density lipoprotein (HDL) and a principal mediator of the reverse cholesterol transfer pathway. Variants of apoA-I have been shown to be associated with hereditary amyloidosis. We previously characterized the G26R and L178H variants that both possess decreased stability and increased fibril formation propensity. Here we investigate the Milano

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Archaea are ubiquitous in forest soils, but little is known about the factors regulating their abundance and distribution. Low molecular weight organic compounds represent an important energy source for archaea in marine environments, and it is reasonable to suspect that archaeal abundance is dependent on such compounds in soils as well, represented by, for example, plant and fungal exudates. To t

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Lightweight wooden-framed constructions have steadily increased their market share in Sweden during the last two decades. Achieving acoustic and vibration comfort in wooden-based buildings is, however, still a challenging task. Wood is high in both strength and stiffness in relation to its weight, but its variability has repercussions on how sound propagates, this triggering sound insulation probl

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The topics of regional innovation systems (RIS) and cross-border regions attract increasing attention, but few studies combine the themes. Further, the existing empirical studies of cross-border innovation and knowledge creation analyse one case at one point in time, thus, making it difficult to assess the progress of integration in the regions, as well as the effect of cross-border innovation pol

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The presence of Fe-bound cyanide ligands in the active site of the proton-reducing enzymes [FeFe]-hydrogenases has led to the hypothesis that such Bronsted-Lowry bases could be protonated during the catalytic cycle, thus implying that hydrogen isocyanide (HNC) might have a relevant role in such crucial microbial metabolic paths. We present a hybrid quantum mechanical/molecular mechanical (QM/MM) s

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The COVID-19 pandemic sparked a global debate on intellectual property rights involving various actors including nation states, civil society, and business. In October 2020, South Africa and India proposed that certain intellectual property rights on COVID-19 health products should be temporarily waivered for the remainder of the pandemic invoking strong opposition from the pharmaceutical industry

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Purpose: The purpose of this paper is to explore political leaders as archetypal brands. Moreover, this study aims to add knowledge to the concept of archetypes in political brand communication. Methodology: This study combines qualitative and quantitative research. Therefore, three cases of different political leaders (Donald Trump, Angela Merkel & Volodymyr Zelensky) are being examined. Seco

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The main purpose of this thesis is to add to the conceptual understanding of gender in management consulting, as portrayed through the lens of popular culture. It is further aimed to highlight the reciprocal relationship between popular culture research and the study of organization/ management consulting studies. Thereby, we hope to contribute to the existing literature that treats gender in mana