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We present an updated characterization of the planetary system orbiting the nearby M2 dwarf GJ 3090 (TOI-177; d=22 pc), based on new high-precision radial velocity (RV) observations from NIRPS and HARPS. With an orbital period of 2.85 d, the transiting sub-Neptune GJ 3090 b has a mass we refine to 4.52 ± 0.47 M>, which, combined with our derived radius of 2.18 ± 0.06 R2, yields a density of 2.40-0

Background: Seafarers constitute a global workforce exposed to unique psychosocial, organisational, and environmental stressors. Despite growing attention to maritime wellbeing, empirical evidence on how these multi level determinants interact to shape mental and physical health remains limited. This thesis aims to identify key determinants of mental health, wellbeing, happiness, and self rated he

The electrification of the transportation sector is a central strategy for decarbonization, yet it raises concerns about the capacity of existing electric power grids to meet increasing demand. This thesis investigates the interaction between large-scale electrified vehicle fleets and the electric power system under the assumption of full transport electrification. The focus is on assessing the re

Despite their geological significance, the thermochemical processes leading to the formation of early carbonate cements remain elusive. To bridge this knowledge gap, we carried out here laboratory-simulated diagenesis on aragonite ooids. They were placed in autoclaves, filled with distilled water, and subjected to varying temperatures and durations. Our results focus on the transformation from ara

The chemokine monocyte chemoattractant protein-1 (MCP-1) plays an important role as chemoattractant for monocytes in atherosclerosis. It is established that MCP-1 is produced by vascular smooth muscle cells, but the underlying mechanisms for its release are not identified. Here, we investigate production and secretion of MCP-1 in primary human coronary artery smooth muscle cells. We demonstrate th

Microalgae, as photosynthetic organisms, are cultivated in photobioreactors for various industrial applications. Light intensity, a critical factor influencing their growth rate, is inherently nonuniform within photobioreactors. In regions distant from the illuminated surface, microalgae experience photolimitation due to insufficient photon availability, hindering optimal activation of the photosy

BackgroundChildren with ADHD are reported to have lower dopamine (DA) and norepinephrine (NE) levels compared to typically developing children. We exploratively investigated how blink rate and pupil diameter, which are considered to be proxies for DA and NE signaling, were related to ADHD symptom severity. Moreover, we tested whether this relation is modulated by auditory white noise stimulation,

Proper arterial versus venous endothelial lineage identity is required to establish a hierarchical network of arteries and veins and prevent the occurrence of life-threatening arteriovenous malformations. The molecular mechanisms that govern arteriovenous lineage specification remain however incompletely understood. Here, we demonstrate that the transcription factor Prdm16 is expressed in arterial

In order to elucidate the multidimensional response mechanism for migration of antibiotics and spread of resistome in riverbed driven by river water level fluctuations, dynamic reactors were set up to simulate the variation of sulfamethazine vertical migration, biotransformation and resistance genes expression according to fluctuation direction and magnitude. The upward fluctuation of water level

This paper examines prominence from a pragmatic, phonological and acoustic-articulatory perspective. Based on results of a corpus-based analysis of Topic prosodic units in four languages (Italian, Brazilian and European Portuguese, and American English), three types of topic prosodic forms (TPFs) are described. Also are reviewed studies reporting phonological organization of English prominence pat

IntroductionThe evidence for assessing whether a single stab injury to the trunk was inflicted by another person in an assault or self-inflicted has primarily been derived from autopsy studies. In this study, we investigate whether victim demographics, crime scene circumstances, and the injury characteristics of assault survivals are interchangeable with homicide characteristics, with a specific f

Polystyrene micro- and nanoplastics (PS-MNPs) are emerging environmental pollutants with potential implications for human health. This study investigated the cytotoxic effects of PS particles by using two different sizes of PS-MNPs (0.25 µm and 1 µm) on non-small cell lung cancer (A549, H460), small cell lung cancer (DMS53, H372), and normal lung epithelial (BEAS-2B) cells as well as on human-deri

Background: Caffeine in doses above 400 mg, approximately four cups of coffee, induces panic attacks in 50% of individuals with panic disorder (PD) and elevates anxiety, but it is not known how individuals with PD respond to normally consumed doses or how caffeine interacts with emotional tasks. Aims: We hypothesized that 150 mg caffeine would increase subjective anxiety (primary outcome) as well

HfO2, one of the most common materials in resistive switching devices, can stabilize in a ferroelectric orthorhombic phase, enabling two nonvolatile polarization states via oxygen displacement in the unit cell. Under certain conditions, ferroelectric and resistive switching can coexist, independently addressable, within one device. This study employs operando spectroscopic analysis to elucidate th

Introduction: The hepatic cytochrome P450 system includes the polymorphic CYP2D6 gene. CYP2D6 ultra rapid metabolizers (UMs) were 10-fold more common in suicide victims than in the general population in a previous study. The aim of this study was to investigate if the occurrence of the CYP2D6 UM genotype differs between subjects with and without previous suicide attempt in patients treated for dep

In this study, we investigated overbank sediments of the first terrace of Sava river in Šabac, exposed at a residential building construction site. Sediment characteristics such as grain size, magnetic susceptibility, chemical composition, and loss on ignition (LOI) at 550 °C and 950 °C were determined at 5 cm resolution, accompanied by visual inspection to assess color, pedogenic structure, and o

Introduction: To increase the sustainability of healthcare, clinical trials must assess the environmental impact of interventions alongside clinical outcomes. This should be guided by Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) and Consolidated Standards of Reporting Trials (CONSORT) extensions, which will be developed by The Implementing Climate and Environmental O