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Advanced melanoma has for long been associated with poor prognosis. Recent advance- ments have improved outcomes; however, many challenges are yet to be overcome. Targeted therapy has in recent years been a good option for patients. Despite positive early responses to the treatment, tumours often grow resistant to these therapies over time rendering them ineffective. The development of resistance

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Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterised by motor and non-motor symptoms, including significant speech impairments. Early and accurate diagnosis is crucial for effective management and treatment. However, traditional diagnostic methods are often limited because they rely on subjective assessments and only detect symptoms after they have become noticeable.

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Gängkriminaliteten och dödsskjutningar har blivit ett allvarligt problem i Sverige, vilket väcker frågor om hur problemet ska hanteras. Införandet av säkerhetszoner har föreslagits som ett verktyg för att bekämpa kriminaliteten och öka tryggheten för medborgarna. Säkerhetszonen ger polisen utökade be- fogenheter att utan konkret brottsmisstanke genomföra kroppsvisitationer och genomsöka fordon i sGang-related crime and fatal shootings have become a serious issue in Swe- den, raising the questions about how the problem should be handled. The in- troduction of security zones has been proposed as a tool to combat crime and enhance public safety. Security zones grant police extended authority to con- duct body searches and search vehicles without concrete suspicion of crime, in order to find w

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Lojalitetsplikten är en allmän rättsprincip i svensk rätt som berör flera olika rättsområden. Principen saknar legaldefinition, men brukar beskrivas som en skyldighet att iaktta eller beakta motpartens intresse. Inom aktiebolagsrätten är den vedertagna uppfattningen att styrelseledamöter och verkställande direktör omfattas av en långtgående lojalitetsplikt gentemot bolaget. För aktieägares vidkommThe duty of loyalty is a general legal principle in Swedish law that influences several areas of law. While the principle lacks a precise legal definition, it is often described as an obligation to observe or consider the interests of the other party. In company law, it is widely accepted that board members and the CEO are bound by an extensive duty of loyalty toward the company. Howev-er, the sit

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Uppsatsen undersöker brottet folkmord med särskilt fokus på uppsåtsrekvisitet och hur det har hanterats av internationella domstolar. Uppsatsen syftar till att analysera rättspraxis från ad hoc-tribunaler som Jugoslavien- och Rwandatribunalen. Uppsatsen tar också upp det pågående målet mellan Sydafrika och Israel vid Internationella domstolen, där Israel anklagas för folkmord mot palestinier i GazThis thesis examines the crime of genocide with a specific focus on the intent requirement and how it has been addressed by international courts. It aims to analyze jurisprudence from ad hoc tribunals such as the International Criminal Tribunal for the Former Yugoslavia and International Criminal Tribunal for Rwanda. The thesis also discusses the ongoing case between South Africa and Israel at the

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Forskningsfråga: Hur förklarar konsumenter hanteringen av gapet mellan hållbarhetsattityd och beteende vid konsumtion av friluftskläder? Syfte: Studien syftar till att undersöka hur konsumenter förklarar och beskriver diskrepansen mellan hållbarhetsattityden och beteendet vid konsumtion av friluftskläder. Vidare belyses detta utifrån teoretiska ramverk gällande hantering av gapet för att tillför

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This work concerns the creasing and folding of a continuum paperboard material model developed by Eric Borgqvist. Creasing is an operation that induces permanent deformation in the material, undertaken for the folding to be performed along a straight fold line without any in-plane cracks. The material model concerned is complex and involves a high degree of anisotropy, and it has earlier been prov

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Background: Scoliosis is a condition where a person's spine is curved and rotated in three dimensions. In severe cases, surgery is needed to straighten the spine. Before such complex procedures, meticulous planning is needed. By performing a CT-scan, images of the spine can be acquired. From these images, it is possible to segment the spine in three dimensions to facilitate the preparation. Ho

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Svenska Kärnbränslehanteringen (SKB) startade ett projekt under 2020 i närheten av Forsmark i Sverige med målet att utöka deformationszonsmodellen till att inkludera hela dräneringsområdet runt om det planerade slutförvaret för använt kärnbränsle. Detta arbete bygger på en lineamentmodell som var skapad för SKB. Denna modell använder sig av magnetiska data tillsammans med höjddata samt data insamlThe Swedish Nuclear Fuel and Waste Management Co. (SKB) started a project in 2020 near Forsmark, Sweden with the aim to expand the deformation zone model to encompass the entire catchment area around the planned repository for spent nuclear fuel. This thesis builds upon a lineament model that was constructed for SKB which utilizes airborne magnetic data supported by airborne Very Low Frequency (VL

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The ability to navigate from breeding sites and wintering grounds has fascinated numerous avian studies examining the bird orientation performances. The migratory avian navigational toolbox consist of route- and map-based orientation, non-compass, vector and compass orientation. The compass orientation consist of celestial and geomagnetic cues, which are divided into the three main compasses known

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Increasing urbanization and the commodification of housing have contributed to limited availability of affordable housing in many cities worldwide. Marked-based rent regulations and the redevelop-ment of post-industrial harbor districts have given rise to the emergence of new-build gentrification in many cities. Sweden, formerly known for its social democratic and welfare state policies, has under

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When a sliding door is opened there is a sudden current peak that the electric network is subjected to. As a result of this it is difficult to design a power supply that operates the door with adequate performance while still maintaining a low power rating. In the current solution the power rating is designed for the sudden peaks and as there is no buffer of energy everything has to be taken direc

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The present study is grounded upon the traditional concepts of cohesion and differentiation in fashion by Simmel (1904) and Bourdieu (1984). The study reviewed these concepts in the social context of sustainable fashion consumption, with consideration of identity construction and expression. Furthermore, the study looked at the literature on certification labels and their value for consumers. Due

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The aim of this master thesis was to develop adaptive control for a quadrotor using Gaussian process regression (GP). Online regression with GPs can provide many benefits as it is a flexible non-linear regression model that can provide uncertainty measures of the estimate. However, online GP regression may also gives rise to problems. Because of the high numerical complexity of GPs, sparse approxi