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Background: Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA-PET/CT) is affecting the management of patients with prostate cancer with biochemical recurrence after radical prostatectomy. The long-term outcomes of tailoring salvage treatment on the basis of PSMA-PET/CT status remain to be determined. Methods: A decision-analytic model was developed to projec

BACKGROUND: So far, the ImmuKnow Immune Cell Function Assay (Cylex, Inc., Columbia, MD, USA) has been used to assess risks of infection and rejection in transplant patients. We hypothesized that the ImmuKnow assay might be used for mortality screening in transplant patients overall.METHODS: In the period of February 2007 to December 2009, at the Uppsala University Hospital, 362 patients who receiv

Background: Patients with hemophilia are reported to have a high prevalence of established and potential risk factors for kidney dysfunction and damage. However, comprehensive studies specifically evaluating kidney function in hemophilia, particularly hemophilia B (HB), are limited, with most research focusing on hemophilia A. Objectives: This study aimed to assess markers of glomerular filtration

Introduction. The fourth edition of the Transatlantic Orthopedic Surgery Webinar 2022 took place on December 12th, 2022. The main theme of the webinar was the treatment of crouch gait in children with cerebral palsy (CP). Speakers from Australia, Canada, China, Germany, India, Poland, Spain, Sweden, Turkey, the United Kingdom, and the United States participated. Results. The first general session

Background: Peritoneal carcinomatosis (PC) from colorectal cancer (CRC) is a metastatic condition associated with poor prognosis. Tumor dissemination within the peritoneal cavity is influenced by inflammatory responses, immune activation, and tumor-matrix interactions, particularly following surgical trauma. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC

This thesis consists of four self-contained papers in the economics of education and labor economics.In the first chapter, we study whether differences in teacher quality across countries are a contributor of international learning gaps. In particular, we study the effects of two dimensions of teacher quality, subject knowledge and didactic skills, on student learning in francophone Sub-Saharan Af

Introduction: Exposure to high acoustic noise levels generated during 7 Tesla (T) magnetic resonance imaging (MRI) may affect auditory function. To better understand these effects, this study examines how such noise exposure influences outer hair cell function in healthy adults, with a focus on the efficiency of a dual hearing protection method. Methods: In this within-subjects longitudinal study,

Background Obstructive sleep apnea (OSA) is associated with autonomic dysfunction and increased cardiovascular risk, but the effects of continuous positive airway pressure (CPAP) on exercise-derived autonomic responses in patients with coronary artery disease (CAD) remain unclear. Methods This study included nonsleepy patients (Epworth Sleepiness Scale score <10) with CAD and OSA (apnea–hypopnea i

BACKGROUND: CFTR modulators, including Elexacaftor/Tezacaftor/Ivacaftor (ETI), have markedly improved clinical outcomes for people with cystic fibrosis (pwCF), but the molecular impact on airway inflammation remains incompletely understood. This study aimed to characterise longitudinal changes in airway inflammation and sputum proteomes following ETI treatment.METHODS: Sputum from pwCF (n = 30) wa

The growing passion for indoor optical wireless networks reflects their immense capability to deliver consistent high-quality data connectivity across diverse indoor environments. This study examines how polarization can be engineered to enhance near-field beam focusing in optical wireless indoor networks using a modular clustered optical phased array aperture. The aperture follows a ceiling-mount

More than 600 million people are living in coastal areas in the world. According to the trend of population migration, the global coastal area population may increase to more than 1 billion by 2050. In a long term, a series of activities such as sea-level rise due to global warming and unpredictable natural disasters increase the extent of coastal erosion. As coastal erosion continues to intensify

Efterfrågan på nybyggnation och behovet av infrastruktursatsningar är en ständig och stor uppgift som kommuner och andra myndigheter arbetar med. Stora krav ställs på att samhällsplaneringen ska ske utifrån ett långsiktigt hållbart perspektiv. Att intensiva och omfattande regn har blivit allt vanligare på senare tid resulterar i att samhällsplaneringen måste anpassas därefter, och flödesanalyser o

The aim of this thesis is to examine if fiction books can be used as a support for young adults in families where one of the parents suffer from mental illness. I have used a qualitative method and have made a content analysis on five fiction books for young adults. The fiction books were found on a list of book recommendations published on Psykiatri Skåne’s webpage dedicated for relatives of peop

Despite prayer being one of the most central tenets of Islam, this subject has drawn the attention of surprisingly little scholarship, especially when it comes to studying its origin against pre-Islamic analogues. Thus, this thesis proposes a reconstruction of the very early history of the fivefold daily Islamic liturgy, attempting also to weigh the extent of the influence that pre-Islamic religio

År 2014 presenterade åtta forskare ett nytt maskininlärningsramverk för artificiell intelligens där två neuronnätverk samverkar för framställning av manipulerat verklighetstroget material. Teknologin har bidragit i värdefulla forskningsframsteg, men kan också användas för framställning av manipulerat intimt material. I samband med teknisk innovation uppstår därmed nya tillvägagångssätt för användaIn 2014, eight researchers presented a new framework for artificial intelligence in which two neural networks collaborate to produce manipulated, realistic material. While this technology has contributed to valuable research advancements, it can also be used for the production of manipulated intimate material. With use of this technological innovation, new methods for users to create realistic por