Filtyp
The fifth generation (5G) of mobile communications introduces improvements on many fronts when compared to its previous generations. Besides the performance enhancements and new advances in radio technologies, it also integrates other technological domains, such as cloud-to-things continuum and artificial intelligence. In this work, the 5G-DIVE Elastic Edge Platform (DEEP) is proposed as the linki
Many Gram-positive pathogenic bacteria employ ribosomal protection proteins (RPPs) to confer resistance to clinically important antibiotics. In Bacillus subtilis, the RPP VmlR confers resistance to lincomycin (Lnc) and the streptogramin A (SA) antibiotic virginiamycin M (VgM). VmlR is an ATP-binding cassette (ABC) protein of the F type, which, like other antibiotic resistance (ARE) ABCF proteins,
The stringent response is a global reprogramming of bacterial physiology that renders cells more tolerant to antibiotics and induces virulence gene expression in pathogens in response to stress. This process is driven by accumulation of the intracellular alarmone guanosine-5′-di(tri)phosphate-3′-diphosphate ((p)ppGpp), which is produced by enzymes of the RelA SpoT homologue (RSH) family. The Gram-
We have studied the accuracy of 16 different density functional theory methods to reproduce experimental data for bond lengths, angles, vibrational frequencies, as well as enthalpies and entropies for the binding of N2, H2, CO and hydride ions to various transition-metal complexes (with Fe, Ni, Cr, Mo andW) with relation to nitrogenase.We show that generalized gradient approximation functionals gi
Willow (Salix spp.) trees have been used commercially since the 1980s to produce renewable energy. Some benefits with these trees are that they can clean soil from heavy metals, reduce the risk of nutrient leakage and eutrophication. They could be an alternative to reduce carbon dioxide emissions from fossil fuel, but they are known to emit high rates of biogenic volatile organic compounds (BVOCs)
Transcriptional profiling of acute leukemia, specifically by RNA-sequencing or whole transcriptome sequencing (WTS), has provided fundamental insights into its underlying disease biology and allows unbiased detection of oncogenic gene fusions, as well as of gene expression signatures that can be used for improved disease classification. While used as a research tool for many years, RNA-sequencing
A flow injection thermal microbiosensor was designed for the simultaneous determination of multiple analytes. The biosensor consisted of five thin-film thermistors which were located along a single microchannel. The device was fabricated on a quartz chip by micromachining. The feasibility of employing this system for the detection of two independent enzyme reactions was demonstrated using two diff
Capsule A combination of several biometric measures enables the reliable sexing of the European Bee-eater Merops apiaster, a species with subtle sex differences in plumage and morphometry. Aims To explore variation in biometrics and their suitability to discriminate sex in adult European Bee-eaters Merops apiaster. Methods We sampled populations of a long-distance migratory species with low sexual
In this study, amino acid functionalized poly(2-hydroxyethyl methacrylate-N-methacrylolyl-l-phenylalanine) [PHEMAPA] cryogel discs were prepared. In this respect, phenylalanine containing N-methacryloyl-(L)-phenylalanine methyl ester (MAPA) was polymerized with 2-hydroxyethyl methacrylate (HEMA) without requirement of any activation step. Laccase bound poly(2-hydroxyethyl methacrylate-N-methacrylo
The Convention on Biological Diversity, and the Nagoya Protocol in particular, provide a framework for the fair and equitable sharing of benefits arising from the utilization of biological resources and traditional knowledge, and ultimately aim to promote capacity-building in the developing world. However, measuring capacity-building is a challenging task due to its intangible nature. By compiling
Aim: To report on the results of the online international consensus process to develop the comprehensive and brief International Classification of Functioning, Disability and Health (ICF) Core Sets for adults with cerebral palsy (CP). Method: An online iterative decision-making and consensus process involved 25 experts, including clinicians and researchers working with adults with CP, an adult wit
This paper presents a bottom boundary layer model for the unsteady and non-uniform flow in the swash zone, by extending the momentum integral method so as to include spatial gradients. The developed model is further incorporated into a hydrodynamic model based on the Nonlinear Shallow Water Equations. Two swash zone cases are examined to investigate the effect of the inclusion of spatial gradients
This chapter revisits the ideas of radical empiricism and sensuous scholarship, embedded in current music education research. Focusing on the development of methodological implications of cultural responsiveness and arts-based research methods, the chapter argues for epistemic openness. The discussion is located within the author’s own experiences of course development for Swedish music teacher st
Atmospheric inversion approaches are expected to play a critical role in future observation-based monitoring systems for surface fluxes of greenhouse gases (GHGs), pollutants and other trace gases. In the past decade, the research community has developed various inversion software, mainly using variational or ensemble Bayesian optimization methods, with various assumptions on uncertainty structure
Creating a more sustainable society is increasingly an urban challenge (Pincetl 2010). Upwards of 50 per cent of the world’s population currently dwell in cities, and this figure is forecast to rise dramatically over the coming decades (Grimm et al. 2008). Cities both concentrate the activities that produce carbon emissions, and suffer disproportionately from their negative impacts such as air pol
Background: The aim of the study was to demonstrate the safety and effectiveness of a suture-mediated vascular closure device to perform hemostasis after an axillary artery access during endovascular procedures on the aortic valve, the aorta and its side branches. Methods: A physician-initiated, international, multicenter, retrospective registry was designed to evaluate the success rate (VARC-2 re
Motivated by the novel coronavirus disease (COVID-19) pandemic, this paper aims to apply Gunter Stein's cautionary message of respecting the unstable to the problem of controlling the spread of an infectious disease. With this goal, we study the effect that delays and capacity constraints have in the test, trace, and isolate (TeTrIs) process, and how they impact its ability to prevent exponential
Bladder exstrophy is a rare congenital malformation leaving the urinary bladder open in the midline of the abdomen at birth. There is a clear genetic background with chromosome aberrations, but so far, no consistent findings apart from 22q11-duplications detected in about 2%–3% of all patients. Some genes are implicated like the LZTR1, ISL1, CELSR3, and the WNT3 genes, but most are not explained m
We consider a spectral problem associated with steady water waves of extreme form on the free surface of a rotational flow. It is proved that the spectrum of this problem contains arbitrary large negative eigenvalues and they are simple. Moreover, the asymptotics of such eigenvalues is obtained.
