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A new technology has emerged the last decade, based on a new group of materials; Soft Magnetic Composites (SMC), instead of laminated steel that facilitates production of products with more integrated, smaller, lighter, less costly and highly efficient electromagnetic machines. The application of this technology is a change of paradigm regarding integrated design and energy efficiency. This articl
According to the Global Burden of Disease study, occupational exposures to particulates, gases and fumes were responsible for 0.36 million deaths and 8.8 million disability-adjusted life years globally in 2015. This thesis focuses on two occupational groups that are at risk for developing adverse health effects from the time they spend in their working environments: cleaning workers and workers in
We report 43 novel genes in the water flea Daphnia pulex encoding 73 predicted neuropeptide and protein hormones as partly confirmed by RT-PCR. MALDI-TOF mass spectrometry identified 40 neuropeptides by mass matches and 30 neuropeptides by fragmentation sequencing. Single genes encode adipokinetic hormone, allatostatin-A, allatostatin-B, allatotropin, Ala(7)-CCAP, CCHamide, Arg(7)-corazonin, DENam
Introduction: Low aerobic fitness, low muscular strength, and obesity have been associated with premature mortality, but their interactive effects are unknown. This study examined interactions among these common, modifiable factors, to help inform more-effective preventive interventions. Methods: This national cohort study included all 1,547,478 military conscripts in Sweden during 1969-1997 (97%-
The shear plate dowel joint (SPDJ) is a novel connection design for use in heavy timber structures. Load transfer between timber members is enabled using a single large diameter dowel and externally glued steel plates. The steel plates are glued to the timber using bond lines of low stiffness and high fracture energy to achieve a uniform shear stress distribution, thus maximizing the load carrying
In a controlled and randomised double-blind study, 26 healthy adult volunteers consumed, for 21 d, 400 ml of a rose-hip drink containing oats (0.7 g/100ml) fermented with Lactobacillus plantarum DSM 9843 (RHL; containing 5 x 10(7) cfu ml(-1)), and 22 volunteers in a second group the same amount of a pure rose-hip drink (RH). Significant increases in the total faecal concentration of carboxylic aci
Background: Nerve growth factor (NGF) and brain-derived neural factor (BDNF) are important for brain function and detectable in the blood. This study explored the longitudinal associations of physical activity and body fat with serum NGF and BDNF in children. Methods: Two waves of measurements were performed 2 years apart in 8- to 11-year-old children, including physical activity using the ActiGra
Rapeseed press cake (RPC), the by-product of rapeseed oil production, contains proteins with emulsifying properties, which can be used in food applications. Proteins from industrially produced RPC were extracted at pH 10.5 and precipitated at pH 3 (RPP3) and 6.5 (RPP6.5). Emulsions were formulated at three different pHs (pH 3, 4.5, and 6) with soy lecithin as control, and were stored for six month
The human gastrointestinal tract (GIT) is home to a large community of microorganisms that contribute to human health. Delivering live bacteria to the gut for therapeutic purposes can thus be highly beneficial. However, delivering live biotherapeutic products or probiotic bacteria to the GIT presents challenges because the cells must remain viable during production, storage, and administration. En
Background: High-resolution computed tomography (HRCT) is dependent on detailed morphology in diagnostic assessment of interstitial lung diseases. Photon-counting CT (PCCT) enables improved resolution while reducing radiation. Purpose: To compare if the image quality, detailed morphology, and radiation dose in HRCT of the lung improves with PCCT compared to energy-integrated CT (EICT). Material an
Objectives Patients with type 2 diabetes mellitus (DM) run lower risk for abdominal aortic aneurysm (AAA, aortic diameter ≥ 30 mm) and its complications. We aimed to evaluate associations between disturbances in glucose metabolism and arterial stiffness, AAA, and abdominal aortic diameter in 65-year-old men. Methods Forty-eight 65-year-old men with screening-detected AAA and 115 men with normal ab
In celiac disease, intestinal transglutaminase (TG2) produces immunogenic peptides by deamidation of gluten proteins. These products drive the celiac immune response. We have previously identified an interaction between gliadin and a food additive, E304i, which prevents gliadin processing (both deamidation and transamidation) by TG2, in vitro. In this study, we investigated if E304i could prevent
BACKGROUND: In Bangladesh, diarrhoea in children under-five is a major public health problem with cost implications. Although under-five diarrhoea mortality and morbidity have declined from 2007 to 2018, change in the economic burden is unknown. This study determined the change in the societal economic burden of under-five diarrhoea in Bangladesh comparing 2007 to 2018.METHODS: A prevalence-based,
Loess provides a valuable terrestrial record of past environmental conditions, including the dynamics and trajectories of air mass circulation responsible for dust transport. Here we explore variations in the luminescence sensitivity characteristics of sedimentary quartz and feldspar as possible tools for identifying changes in source down a loess-palaeosol sequence (LPS). Luminescence sensitivity
The capability of the antibody (Ab) repertoire to mount a response to appropriate epitopes on infectious agents will strongly affect the ability of the immune system to provide protection against disease. Certain epitopes may be poor inducers of immunity but are nevertheless able to promote biologically important protection when recognized by the immune repertoire. We have investigated the recogni
BACKGROUND: Clinical guidelines seldom provide in depth information about the most suitable type and intensity of exercise to obtain optimal benefit in different subgroups of T2D individuals. The aim of this study was to examine the effect of group exercise training on exercise capacity, insulin sensitivity and HbA1c in women with diabetes. METHODS: Twenty-two women with T2D participated in a supe
How are public spaces regulated in tourist cities? In this doctoral dissertation I seek to answer this question by exploring the intersections between urban tourism and public space regulation. I argue that public space regulation substantially differs from the tourist to the non-tourist zone. This thesis contradicts the common belief that public space regulation may vary from city to city, but re
The structure, biosynthesis, and metabolism of proteoglycans in the HL-60 human promyelocytes were studied by metabolic labeling in culture with [35S]sulfate, [3H]glucosamine, [3H]serine, and [3H]leucine. These cells synthesize a single predominant species of intracellular proteoglycan with an approximate molecular weight of 100,000. The cells contain about 1 μg of proteoglycan/million cells. The
Spark ablation is an established method for generating aerosol nanoparticles. By changing the electrodes, synthesis of monometallic, multimetallic and semiconducting nanoparticles has been demonstrated. Apart from using electrodes of specific composition, compositional tuning of bimetallic nanoparticles during synthesis has recently been demonstrated (Kohut, et al., 2021). In many applications, it
Enzyme-responsive hydrogels, formed by step growth photopolymerization of biscysteine peptide linkers with alkene functionalized polyethylene glycol, provide interesting opportunities as biomaterials and drug delivery systems. In this study, we developed stimuli-responsive, specific, and cytocompatible hydrogels for delivery of anti-inflammatory drugs for the treatment of inflammatory skin disease
