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Background: Adequate resource allocation is an important factor to ensure equity in health care. Previous reimbursement models have been based on age, gender and socioeconomic factors. An explanatory model based on individual need of primary health care (PHC) has not yet been used in Sweden to allocate resources. The aim of this study was to examine to what extent the ACG case-mix system could exp
Growing demand for transport biofuels in the EU is driving an expansion of the industry in developing countries. Large-scale production of energy crops for biofuel, if mismanaged, could cause detrimental environmental and social impacts. The aim of this study is to examine whether the newly adopted EU Directive 2009/28/EC and its sustainability certification system can effectively ensure sustainab
Therapy-induced resistance remains a significant hurdle to achieve long-lasting responses and cures in cancer patients. We investigated the long-term consequences of genetically impaired angiogenesis by engineering multiple tumor models deprived of endoglin, a co-receptor for TGF-beta in endothelial cells actively engaged in angiogenesis. Tumors from endoglin-deficient mice adapted to the weakened
The topological characteristics of an IEEE 802.16 mesh network including the tree’s depth and degree of its nodes affect the delay and throughput of the network. To reach the desired trade-off between delay and throughput, all potential trees should be explored to obtain a tree with the proper topology. Since the number of extractable tree topologies from a given network graph is enormous, we use
Knowledge of the forest biomass and its change in time is crucial to understanding the carbon cycle and its interactions with climate change. LiDAR (Light Detection and Ranging) technology, in this respect, has proven to be a valuable tool, providing reliable estimates of aboveground biomass (AGB). The overall goal of this study was to develop a method for assessing AGB using a synergy of low poin
This document describes the technical layout and the expected performance of the Straw Tube Tracker (STT), the main tracking detector of the PANDA target spectrometer. The STT encloses a Micro-Vertex-Detector (MVD) for the inner tracking and is followed in beam direction by a set of GEM stations. The tasks of the STT are the measurement of the particle momentum from the reconstructed trajectory an
Objective:To compare the diagnostic accuracy of CSF biomarkers and amyloid PET for diagnosing early-stage Alzheimer disease (AD).Methods:From the prospective, longitudinal BioFINDER study, we included 122 healthy elderly and 34 patients with mild cognitive impairment who developed AD dementia within 3 years (MCI-AD). -Amyloid (A) deposition in 9 brain regions was examined with [F-18]-flutemetamol
Learning from incidents is considered a very important source for learning and improving safety in the process industries. However, the effectiveness of learning from reported incidents can often be ques-tioned. Therefore, there is a need to be able to evaluate the effectiveness of learning from incidents, and for that purpose we need methods and tools. In this paper, a method is described for eva
Photodynamic therapy (PDT) is one of the most interesting methods of photo treatment. In general, PDT is a modality for the treatment of non-muscle invasive tumors. PDT is very well suited in managing bladder cancer, as the bladder is accessible by endoscopy and the tumors are most often limited to the mucosa or sub-mucosa. PDT is likely more useful for patients with recurrent tumors after convent
Purpose The aim of this paper is to explore key challenges of adopting, designing and managing performance-based contracts (PBC) for advanced logistics services, as seen by providers. The shift towards performance-based solutions has proved challenging since providers often struggle to link performance to their payment. Despite such managerial challenges, empirical research in this area has been l
SNP allelic copy number data provides intensity measurements for the two different alleles separately. We present a method that estimates the number of copies of each allele at each SNP position, using a continuous-index hidden Markov model. The method is especially suited for cancer data, since it includes the fraction of normal tissue contamination, often present when studying data from cancer t
During the latest years there has been a strategic decisive change when it comes to how the larger producers regard and treat their subcontractors. This is partly due to the increasing globalization and the fact that the economy is becoming more and more knowledge and networks based. The subcontractors are facing higher demands from the producers to deliver system solutions with more complex compo
The Swedish technical consultancy firms are today facing a number of exciting challenges. A majority of the firms’ larger customers have already established themselves in the international market. Simultaneously they have also begun to appreciate the need of a closer cooperation with a selected number of their suppliers. Hence, opportunities arise for the technical consultants to take on a larger
Background: Customers for buses and coaches on the European market ask for complete vehicles from one supplier. Since Scania CV are only manufacturing chassis, their sales companies must co-operate with body builders in order to offer a complete product and service backup. This means that the sales companies in connection with every order have to deal with two order processes, one for Scania CV an
Purpose: The purpose of this thesis is to create an integrative understanding of how OBCs are fostered by developing a framework for strategic implementation. Methodology: The chosen method is of an explorative nature with an abductive approach. The authors will develop an integrated OBC framework by synthesising relevant brand community literature. This OBC framework will then be scrutinized by e
Accessibility is something often taken for granted in our society, but it is a necessity for people with disabilities. Railway stations are a public place and are often a connecting point for several modes of transport. Design of railway stations in terms of accessibility for persons with disabilities is governed by several national and international governing documents. The purpose of this thesis
Soil degradation has developed into a global problem that threatens food security of millions of people by annually causing serious damage and lowering productivity of hundreds of millions of hectares of arable land. Soil conservation measures that are aimed at abating or preventing various types of soil degradation can thus hold one of the keys to solving the worsening global food crisis. This pa
