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Small molecules increase direct neural conversion of human fibroblasts 1Scientific RepoRts | 6:38290 | DOI: 10.1038/srep38290 www.nature.com/scientificreports Small molecules increase direct neural conversion of human fibroblasts Ulrich Pfisterer1,2, Fredrik Ek3, Stefan Lang2,4, Shamit Soneji2,4, Roger Olsson3 & Malin Parmar1,2 The generation of human induced neurons (hiNs) via exogenous delivery

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_sci_rep.pdf - 2026-04-27

Thesis Purpose: This study aims to enhance the understanding of factors that discourage consumers from buying pre-owned fashion in a multichannel retail setting. Methodology: Rooted in a qualitative and exploratory method, this study is further guided by an abductive approach. By embracing the essence of the social constructivist epistemology and a relativistic ontological standpoint, it delves i

The study examines the narratives of the Decembrist revolt created in and around Russian state-funded cinema. By exploring the narratives surrounding a particular instance of political dissent in the past, the research seeks to uncover the factors that impact on the negotiation of cultural memory between the text and the audience in the context of state-influenced media. This exploration is based

The construction of episodic memory is an automatic process. Event segmentation theory proposed that segmentation of the continuous perceptual stream into separate memory events occurs when changes in external boundaries lead to changes in internal perceptual and conceptual boundaries. The influence of perceptual and conceptual boundaries on episodic memory encoding has been the subject of intensi

The Nordic country of Sweden portrays itself as a leader in sustainable development and human rights advocacy. However, the expansion of what is portrayed as “green” mining activities in Sami territories creates cumulative pressure on traditional livelihoods like reindeer husbandry, which raises questions about the sustainability narrative. Previous research has focused on Swedish policy documents

Cytostatika är läkemedel som används för att behandla cancer genom att hämma eller stoppa celldelning. De används även som immunhämmande medel, till exempel vid organtransplantationer och autoimmuna sjukdomar. Eftersom dessa läkemedel påverkar cellers tillväxt kan de vara skadliga även i mycket små mängder om de hamnar i miljön. Cytostatika har upptäckts i ytvatten, grundvatten och dricksvatten i Introduction: Cytostatic pharmaceuticals are increasingly detected in the aquatic environment, raising concerns due to their persistence and toxicity. Background: Conventional wastewater treatment processes do not effectively remove these compounds. Advanced oxidation processes, such as ozonation, are needed to degrade cytostatic pharmaceuticals during wastewater treatment. However, these process

A Credit Default Swap spread is a reliable measure of credit risk as it is the compensation demanded by a party to bear this risk. Officially, credit risk is denoted as credit ratings announced by credit rating agencies. Since rating announcements contain information regarding credit risk, the market should incorporate this new information into the CDS spread. The aim of this study is to investiga

This study investigates if there are any advantages in increasing foreign direct investments for members of the Association of South Asian Nations (ASEAN) regional integration area. The study explains the effect that regional integration, preferential trade agreements and free trade areas have on attracting foreign direct investments. Different aspects of regional integration are used to explain w

Relapsed or recurrent breast cancer is the chief cause of breast cancer related deaths and it is estimated that one-third of breast cancer patients would likely suffer a relapse. Due to high mortality and incidence, recurrent breast cancer requires better means of prediction, prevention and treatment. The AFFIRM platform uses recombinant antibody technology and selected reaction monitoring (SRM) m

Gas cooling is a technique used within the fire service to reduce the risks of the hot gaseous layer and create a better visibility. It is achieved by applying water into the gaseous layer. Successfully performing or implementing this technique is something that has not yet been accomplished in every brigade. This work has been focused on different parameters that affect gas cooling and is studie

The growth in Scania is expected to increase by developing Scania’s polycentric structure and create regional expansion. This regional expansion will be developed partly by investments in infrastructure, which are expected to generate better accessibility. The aim of this essay is to investigate a specific train investment in north-eastern Scania, Pågatåg Nordost, and its impacts on development an

3D-modell av höftbenet kan hjälpa till att förutspå artros Det är viktigt att förebygga sjukdomar innan de bryter ut. Vanliga 2D-röntgenbilder är inte alltid tillräckligt noggranna men med 3D-modeller kan tidiga tecken på artros lättare identifieras. Vi strävar för att få fram 3D-bilder av höften från vanliga röntgenbilder.Osteoarthritis and osteoporosis are two medical conditions involving the hip which affect the life quality of many people worldwide. These two diseases are diagnosed with 2D imaging by analysis of radiological measures, bone mineral density and joint space. Computed Tomography (CT) can provide 3D images of the hip, but has higher cost and imposes a higher radiation dose to the patient. Another op

This paper aims to examine whether the Federal Communications Commission’s (FCC) debate during 2017 regarding the bill “Restore internet Freedom” can be understood through a theoretical neo-liberal and social-liberal ideological perspective. The purpose of this paper is to clarify and bring an understanding of what was said in the debate regarding the bill, by trying to interpret what political id

Research Question: How does international knowledge and its sources impact the strategic entrepreneurship of internationalized Swedish SMEs? Methodology: A qualitative research of Swedish SMEs, where the research was predominantly cross-sectional in nature. 17 firms were investigated and semi-structured interviews were the primary source of data. The data was analyzed in an inductive matter. TheResearch Question: How does international knowledge and its sources impact the strategic entrepreneurship of internationalized Swedish SMEs? Methodology: A qualitative research of Swedish SMEs, where the research was predominantly cross-sectional in nature. 17 firms were investigated and semi-structured interviews were the primary source of data. The data was analyzed in an inductive matter. The

Reducing microorganisms by UV light is has been commonly used for drinking water for many years. In other liquid products like apple juice it is a rather novel application. The advantages would be that quality parameters like aromas and vitamins are less affected by the UV treatment compared to a heat treatment. Furthermore it would probably be cheaper, as the lamps need less electrical energy tha