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Implantable cardioverter defibrillator use in arrhythmogenic right ventricular cardiomyopathy in North America and Europe

Background and Aims: Implantable cardioverter-defibrillators (ICDs) are critical for preventing sudden cardiac death (SCD) in arrhythmogenic right ventricular cardiomyopathy (ARVC). This study aims to identify cross-continental differences in utilization of primary prevention ICDs and survival free from sustained ventricular arrhythmia (VA) in ARVC. Methods: This was a retrospective analysis of AR

Markanvändning vid byggnation av höghastighetsjärnväg; en jämförelsestudie mellan höghastighetsjärnväg på bank och höghastighetsjärnväg på viadukt.

In the construction of high-speed railways, an important starting point is to make as little Intrusion on land as possible, therefore it is of high importance to carefully investigate which construction alternatives are the most advantageous. The purpose of this work is to compare and evaluate land use and building on viaduct. The work will be based on literature and interview studies. Sections of

In vivo evaluation of electron mediators for the reduction of methemoglobin encapsulated in liposomes by using electron energies produced by red blood cell glycolysis

Previous studies clarified that the electron enriched NADH and NADPH by RBC glycolysis could be used in an extracellular chemical reaction, where electron energies are extracted by an electron mediator methylene blue (MB). The reduced form of MB permeates the phospholipid bilayer of liposomes and reduce encapsulated ferric methemoglobin (metHb) to ferrous hemoglobin. Moreover, in vitro screening s

What about disposition? Exploring millennials’ clothing disposal behaviours in fashion-oriented impulse buying.

The frequent restocking of stores and constant promotional offers associated with fast fashion presents the physical cues for consumers to engage in fashion-oriented impulse buying. This consumption behaviour has led to over consumption and the underutilization of clothes, adding to the problems of textile waste all over the world. Despite the increasing interest in consumers’ disposition behaviou

En MIFO fas 1-inventering av förorenade områden : kvarnar med kvicksilverbetning Jönköpings län

Sverige har en lång tradition av industriell verksamhet vilket har lett till att områden har förorenats. Jönköpings län har bland annat präglats av kvarnverksamhet där betning av utsäde bedrivits. Betning utfördes för att skydda sädeskornets ytskikt mot svampangrepp när det såddes ut på åkrarna. Betningsmedlet som användes var Panogen som är en metylkvicksilverförening. Användningen av detta betni

Evaluation of wire-line well logs from the borehole Kyrkheddinge-4 by comparison to measured core data

Populärvetenskaplig sammanfattning: Utvärdering av borrhålsloggar. Syftet med detta examensarbete var att göra en utvärdering av wireline borrhålsloggar från borrhålet Kyrkheddinge-4, 3 km öster om Staffanstorp i Skåne. Den undersökta delen av borrhålet Kyrkheddinge-4 befinner sig inom den potentiella reservoarsandstenen, Lundasandstenen. Wireline borrhålsloggar är geofysiska verktyg som används This study is an evaluation of formation characteristics, as derived from wire-line well logs, of the Lund Member in the borehole Kyrkheddinge-4, 3 km east of Staffanstorp, Skåne, Sweden, through the comparison to measured core data. The purpose is to assess the feasibility of using some of the porosity and permeability equations and cross-plots derived for the investigated section and applying th

Exploring financing of Swedish primary schools in the 19th century

Primary schooling was made mandatory in Sweden in 1842. Previous literature on this well-known reform centres on the related political discussions at central level. This thesis examines how local school financing evolved in the 19th century in response to increased engagement from the central government and why it evolved the way it did. A particular focus is on the largely overlooked local level

Expression of the global regulator SATB1 is an independent factor of poor prognosis in high grade epithelial ovarian cancer

Background: The global gene regulator Special AT-rich sequence-binding protein1 (SATB1) has been reported to reprogramme tumour cells into a more malignant phenotype and associate with poor clinical outcome in several cancer forms. In this study, we investigated the molecular correlates and prognostic impact of SATB1 expression in human epithelial ovarian cancer (EOC). Findings: Immunohistochemica

A Virtual Reality Version of the Trier Social Stress Test: a Pilot Study

One of the most common methods of inducing stress in the laboratory in order to examine the stress response in healthy and clinical populations is the Trier Social Stress Test (TSST). Briefly, the participant is asked to deliver a speech and to perform an arithmetic task in front of an evaluating committee. The committee, consisting of three trained actors, does not respond emotionally during the

Novel gene targets detected by genomic profiling in a consecutive series of 126 adults with acute lymphoblastic leukemia

In contrast to acute lymphoblastic leukemia in children, adult cases of this disease are associated with a very poor prognosis. In order to ascertain whether the frequencies and patterns of submicroscopic changes, identifiable with single nucleotide polymorphism array analysis, differ between childhood and adult acute lymphoblastic leukemia, we performed single nucleotide polymorphism array analys

Cholesterol in women at high cardiovascular risk is less successfully treated than in corresponding men

Objective To assess the use of lipid-lowering therapy in patients with known coronary heart disease (CHD), cerebrovascular disease or diabetes in a community-based population in Sweden considering expert recommendations. Methods A random sample of individuals aged >= 40 years who were surveyed in 1993-1994 were revisited 10 years later during 2003-2004 (n=724). A clinical investigation focused on

Introgression and rapid species turnover in sympatric damselflies

Background: Studying contemporary hybridization increases our understanding of introgression, adaptation and, ultimately, speciation. The sister species Ischnura elegans and I. graellsii (Odonata: Coenagrionidae) are ecologically, morphologically and genetically similar and hybridize. Recently, I. elegans has colonized northern Spain, creating a broad sympatric region with I. graellsii. Here, we r

The effect of different criteria on the number of patients blind from open-angle glaucoma

Background: The prevalence of blindness and visual impairment from glaucoma is influenced by the criteria used to define these entities, which differ between countries and regions, as well as among published reports. The objective of the present study was to ascertain the extent to which different criteria of blindness and visual impairment influence estimates of the number of patients classified

UV-B-induced DNA damage mediates expression changes of cell cycle regulatory genes in Arabidopsis root tips

Even though a number of studies have shown that UV-B radiation inhibits plant growth and regulates the cell cycle progress, little is known about the molecular and cellular mechanisms. Here, we developed a synchronous root-tip cell system to investigate expression changes of cell cycle marker genes and DNA damage under UV-B radiation. Expression analysis of cell cycle marker genes revealed that G1