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Predictors of default from follow-up care in a cervical cancer screening program using direct visual inspection in south-western Nigeria

Background: Increasingly evidence is emerging from south East Asia, southern and east Africa on the burden of default to follow up care after a positive cervical cancer screening/diagnosis, which impacts negatively on cervical cancer prevention and control. Unfortunately little or no information exists on the subject in the West Africa sub region. This study was designed to determine the proportio

Differing Risk Factor Profiles of Ischemic Stroke Subtypes: Evidence for a Distinct Lacunar Arteriopathy?

BACKGROUND AND PURPOSE: Differences in risk factor profiles between lacunar and other ischemic stroke subtypes may provide evidence for a distinct lacunar arteriopathy, but existing studies have limitations. We overcame these by pooling individual data on 2875 patients with first-ever ischemic stroke from 5 collaborating prospective stroke registers that used similar, unbiased methods to define ri

Patterns of background factors related to early RA patients' conceptions of the cause of their disease

The aim of the present study was to identify patterns of background factors related to the early RA patients' conceptions of the cause of the disease. Conceptions from a qualitative study formed the basis for the stratification of 785 patients from the Swedish EIRA study answering a question about their own thoughts about the cause to RA. Logistic regression analyses were used to explore the assoc

Electron and Hole Contributions to the Terahertz Photoconductivity of a Conjugated Polymer:Fullerene Blend Identified

Time-resolved terahertz spectroscopy was employed for the investigation of charge-transport dynamics in benzothiadiazolo-dithiophene polyfluorene ([2,7-(9,9-dioctylfluorene)-alt-S,S-(4',7'-di-2-thieny1-2',1',3'-benzothiadiazole)]) (APFO-3) polymers with various chain lengths and in its monomer form, all blended with an electron acceptor ([6,6]-phenyl-C61-butyric acid methyl ester, PCBM). Upon phot

Designed Quasi-1D Potential Structures Realized in Compositionally Graded InAs1-xPx Nanowires.

III-V semiconductor heterostructures are important components of many solid-state optoelectronic devices, but the ability to control and tune the electrical and optical properties of these structures in conventional device geometries is fundamentally limited by the bulk dimensionality and the inability to accommodate lattice-mismatched material combinations. Here we demonstrate how semiconductor n

Electrochemical and XAS investigation of oxygen reduction reaction on Pt-TiO2-C catalysts

Pt-TiO2-C composites with different titanium oxide loading were synthesized by photo-deposition and chemical vapor deposition methods. The changes in their electronic properties improve the electrochemical activity toward the oxygen reduction reaction (ORR) compared to the Pt-C catalyst synthesized at the same conditions. The platinum samples were physically characterized by means of Transmission

Microscopic approach to second harmonic generation in quantum cascade lasers

Second harmonic generation is analyzed from a microscopical point of view using a non-equilibrium Green's function formalism. Through this approach the complete on-state of the laser can be modeled and results are compared to experiment with good agreement. In addition, higher order current response is extracted from the calculations and together with waveguide properties, these currents provide t

Experimental verification of reciprocity relations in quantum thermoelectric transport

Fundamental symmetries in thermoelectric quantum transport, beyond Onsagers relations, were predicted two decades ago but have to date not been observed in experiments. Recent works have predicted the symmetries to be sensitive to energy-dependent, inelastic scattering, raising the question whether they exist in practice. Here, we answer this question affirmatively by experimentally verifying the

Free carrier absorption and inter-subband transitions in imperfect heterostructures

We present the results of a quantum mechanical modelling of the free carrier absorption (FCA) in semiconductor heterolayers. Elastic and inelastic scatterers are considered with emphasis on the interface defects (optical phonons) contributions to the induced photon absorption for elastic (inelastic) scatterers. Various approaches to FCA are also presented (perturbation, Green's function technique)

Self-rated health and mortality in individuals with diabetes mellitus: prospective cohort study

Objectives: To investigate whether low self-rated health (SRH) is associated with increased mortality in individuals with diabetes. Design: Population-based prospective cohort study. Setting: Enrolment took place between 1992 and 2000 in four centres (Bilthoven, Heidelberg, Potsdam, Umea) in a subcohort nested in the European Prospective Investigation into Cancer and Nutrition. Participants: 3257

The electronic structure and reflectivity of PEDOT:PSS from density functional theory

The geometric and electronic structure of condensed phase organic conducting polymer PEDOT:PSS blends has been investigated by periodic density functional theory (DFT) calculations with a generalized-gradient approximation (GGA) functional, and a plane wave basis set. The influence of the degree of doping of the PEDOT polymer on structural and optical parameters such as the reflectivity, absorbanc

Giant hollow fiber formation through self-assembly of oppositely charged polyelectrolyte brushes and gold nanoparticles

We report on the use of binary mixtures of oppositely charged gold nanoparticles (AuNPs) and spherical polyelectrolyte brushes (SPBs), consisting of a polystyrene core onto which long polystyrene sulfonate chains are grafted, as a simple model system to investigate the influence of directional interactions on self-assembly. We demonstrate that the mixing ratio, i.e., the number of AuNPs per SPB, h

The burden, distribution and risk factors for cervical oncogenic human papilloma virus infection in HIV positive Nigerian women

Background: The expected reduction in cervical cancer incidence as a result of increased access to antiretroviral therapy is yet to be seen. In this study we investigated the effect of HIV infection and treatment on high-risk (hr) human papilloma virus (HPV) prevalence and distribution. Methods: Cervical cells from 515 (220 HIV positive and 295 HIV negative) women, recruited during community cervi

Unraveling of free-carrier absorption for terahertz radiation in heterostructures

The relation between free-carrier absorption and intersubband transitions in semiconductor heterostructures is resolved by comparing a sequence of structures. Our numerical and analytical results show how free-carrier absorption evolves from the intersubband transitions in the limit of infinite number of wells with vanishing barrier width. It is explicitly shown that the integral of the absorption

Evaluation of the impact of genetic polymorphisms in glutathione-related genes on the association between methylmercury or n-3 polyunsaturated long chain fatty acids and risk of myocardial infarction: a case-control study

Background: The n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid, which are present in fish, are protective against myocardial infarction. However, fish also contains methylmercury, which influences the risk of myocardial infarction, possibly by generating oxidative stress. Methylmercury is metabolized by conjugation to glutathione, which facilitates elimination. Glut

Molecular Etiology of Graves’ Disease and Associated Ophthalmopathy

Graves' disease (GD) is a complex autoimmune disorder characterized by hyperthyroidism and diffuse goitre. 25-50% of the patients with GD develop eye symptoms, Graves' ophthalmopathy (GO). The overall aim of this thesis was to explore the molecular etiology of GD and GO. By studying gene expression in Studies I, III, and IV, we demonstrated that adipocyte-related immediate early genes (IEGs) incl