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OBJECTIVES: Measurement of transglutaminase autoantibodies (TGAA) is considered to be the most efficient single serologic test for celiac disease (CD) by the American Gastroenterological Association Institute. We hypothesized that a large international collaborative effort toward improving and standardizing TGAA measurement is both feasible and necessary. The primary aim of this workshop is to com

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A novel monolithic macroporous material was developed by cross-linking hen egg albumin (HEA) and chitosan with glutaraldehyde at subzero temperatures. A macroporous cryogel structure allowed efficient mass transport of solutes within the material. In one application, albumin was partially replaced with active enzymes (glucose oxidase and horseradish peroxidase) resulting in the production of macro

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Evolutionary change results from selection acting on genetic variation. For migration to be successful, many different aspects of an animal's physiology and behaviour need to function in a co-coordinated way. Changes in one migratory trait are therefore likely to be accompanied by changes in other migratory and life-history traits. At present, we have some knowledge of the pressures that operate a

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Nonlinear propagation of electromagnetic waves is an important problem in optics. Often the properties of the nonlinear media are not fully understood. The solution of an inverse problem can provide an aid to that understanding. An inverse transmission problem is posed; it is one of reconstructing the medium parameters, by measurement of a wave that has been propagated through the nonlinear mediu

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Motivation: Multimillion-probe microarrays allow detection of gains and losses of chromosomal material at unprecedented resolution. However, the data generated by these arrays are several-fold larger than data from earlier platforms, creating a need for efficient analysis tools that scale robustly with data size. Results: We developed a new aberration caller, Ultrasome, that delineates genomic cha

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Using the Cayley–Hamilton theorem and unique solubility of scalar Volterra convolution equations of the second kind, the inverse problem of determining the four time-dependent susceptibility dyadics of a linear, homogeneous, bi-anisotropic slab from generic scattering data at oblique incidence is shown to be well posed. An explicit formula for the crucial step is given.

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We present a physiologically stable porcine model designed for sequential assessments of pharmacological effects on mean hemispheric cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) at sustained normocapnia. The dynamic influence of continuously administered fentanyl (0.040 mg.kg-1.h-1 i.v.), nitrous oxide (70%) and pancuronium (0.30 mg.kg-1.h-1 i.v.) on these variables was

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In this paper, a fully automatic method for the diagnosis of pulmonary embolism (PE) from V/Q-scans is presented. Image analysis is applied to the ventilation and the perfusion images obtained in the V/Q-scan. The difference of the ventilation and the perfusion is calculated after transformation and hot-spot reduction of the images. From this difference image the integral of the underperfused area

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Ferrous sulphate gel dosimetry has the potential for measurement of absorbed dose distributions in proton therapy. The chemical properties of the gel are altered according to the radiation dose and these changes can be evaluated in three dimensions using MRI. The purpose of this work was to investigate the properties of a ferrous gel used with clinical proton beams. The gel was irradiated with bot

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Leaf area index (LAI) of boreal ecosystems were estimated with optical instruments at the Laxemar and the Forsmark investigation areas in Sweden. The aim was to study the relationship between LAI and the normalized difference vegetation index (NDVI) from Landsat-5 and SPOT and evaluate the applicability of the MODIS (Moderate Resolution Imaging Spectroradiometer) LAI product for small boreal regio

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We investigate the possibility to use coated metallic nanoparticles for single-molecule surface-enhanced spectroscopy by extending the Mie theory. The aggregates of metallodielectric spheres of Au and Ag show a strong local intensity enhancement in the cavity between particles, which can result in up to a 10(14)-fold increase for surface-enhanced Raman scattering. We also examine the thickness of

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Islet function is regulated by a number of different signals. A main signal is generated by glucose, which stimulates insulin secretion and inhibits glucagon secretion. The glucose effects are modulated by many factors, including hormones, neurotransmitters and nutrients. Several of these factors signal through guanine nucleotide-binding protein (G protein)-coupled receptors (GPCR). Examples of is

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An academic 12-lead electrocardiogram (ECG) core laboratory aims to provide the highest possible quality ECG recording, measurement, and storage to aid clinicians in research into important cardiovascular outcomes and to maximize the credibility of scientific results based solely, or in part, on ECG data. This position paper presents a guide for the structure and function of an academic ECG core l

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In as tationary stochastic process the wave-length and amplitude are defined as the difference in time and height between a crest and the following trough. The distributions of these quantities are of great practical importance, but no closed form expressions are known at present. In previous papers we have presented an approximation which gives correct upper and lower bounds, regardless of the co

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We study some fundamental computational geometry problems with the goal to exploit structure in input data that is given as a sequence C = (p(1), p(2), . . . ,p(n)) of points that are "almost sorted" in the sense that the polygonal chain they define has a possibly small number, k, of self-intersections, or the chain can be partitioned into a small number, X, of simple subchains. We give results th

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The variation of hole population in the resonant states of B-doped Si excited by sequences of short electric-field pulses has been investigated by the technique of time-resolved step-scan far-infrared spectroscopy. From the variation of the p(3/2) absorptions, we find that the hole population in the ground state decreases continuously with the sequential electric pulses, as a result of the breakdo

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The objectives are to relate species distributions among 110 non-fertilized grassland ('dry meadow') sites in southeastern Sweden to soil chemical, physical, exposure and management variables using correlation, stepwise regression and factor (PCA) analysis based on quantitative data. It was suggested that soil acidity variables (pH, base saturation, exchangeable Ca, Al, Mn,and Fe), P, K, Mg, and N

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Measurement of mental workload has been widely used for evaluation of aircraft design, mission analysis and assessment of pilot performance during flight operations. Heart rate is the psychophysiological measure that has been most frequently used for this purpose. The risk of interference with flight safety and pilot performance, as well as the generally constrained access to flights, make it diff