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We show here, by using surface biotinylation, followed by Western blotting or surface plasmon resonance analysis, that very low levels of S100A8 and/or S100A9 can be detected on the surface of THP-1 cells or freshly isolated human monocytes. This was supported by immune-electron microscopy where we observed membrane-associated expression of the proteins restricted to small patches. By using confoc
Since its establishment, the Android applications market has been infected by a proliferation of malicious applications. Recent studies show that rogue developers are injecting malware into legitimate market applications which are then installed on open source sites for consumer uptake. Often, applications are infected several times. In this paper, we investigate the behavior of malicious Android
Background More than one in five patients who undergo treatment for breast cancer will develop breast cancer-related lymphedema (BCRL). BCRL can occur as a result of breast cancer surgery and/or radiation therapy. BCRL can negatively impact comfort, function, and quality of life (QoL). Manual lymphatic drainage (MLD), a type of hands-on therapy, is frequently used for BCRL and often as part of com
Individual and trophic efficiencies of size-structured communities are derived from mechanistically based principles at the individual level. The derivations are relevant for communities with a size-based trophic structure, i.e. where trophic level is strongly correlated with individual size as in many aquatic systems. The derivations are used to link Lindeman's trophic theory and trophic theory b
Attosecond pulses are used to study electron dynamics in atoms and molecules. In this thesis, schemes to control the generation of attosecond pulses and pulse-shaping techniques to compress the pulses are presented. Generation of attosecond pulses requires high intensity, which is reached by focusing a pulsed femtosecond laser. The emitted pulses come isolated or in an attosecond pulse train (APT
The relationship between palynological diversity and floristic diversity was studied on the basis of sediment surface sample pollen data from nine small lakes and vegetation data within a 250 m radius from the lake shore of each. The nine study areas are situated in the patchy cultural landscape of Southern Estonia and were chosen to represent landscape changes along a gradient from closed forest
Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between genetic, epigenetic and environmental factors. While the major environmental factors, diet and activity level, are well known, identification of the genetic factors has been a challenge. However, recent years have seen an explosion of genetic variants in risk and protection of T2D due to the technical developm
Popular Abstract in Swedish Presenterar resultat inom algoritmer och datastrukturer för att hantera sekventiella data (strängar), med användningar bland annat inom datakomprimering. Särskilt behandlas varianter av suffixträd och näraliggande ämnen, som sortering av suffix. Vad gäller komprimering behandlas modellering av källor med hjälp av både strängbaserade metoder (t.ex. Ziv-Lempel) och probabThis doctoral dissertation presents a range of results concerning efficient algorithms and data structures for string processing, including several schemes contributing to sequential data compression. It comprises both theoretic results and practical implementations. We study the suffix tree data structure, presenting an efficient representation and several generalizations. This includes augmenti
DNA- cationic amphiphile and DNA-cationic polymer systems were studied with respect to the intermolecular interactions, as well as structure and stability of formed complexes. The thesis is divided in two parts: one section is a summary and the other section contains five papers. The summary is organized as follows; Chapter 2 gives an overview on the behavior of polyelectrolytes in solutions with
The mechanisms of protein folding and aggregation are investigated by computer simulations of all-atom and reduced models with sequence-based potentials. A quasi local Monte Carlo update is developed in order to efficiently sample proteins in the folded phase. A small helical protein, the B-domain of staphylococcal protein A, is studied using a reduced model. In the thermodynamically favoured topo
This text offers some principal and methodogical issues on studies of timbre in words, music and vocal performance. Timbral relationships between word and music can be conceptualized as a continuum following an fictive axis running from meaning and timbre of words, through melody and music to performance. Sometimes the order might be different, but the ingredients will always be there. To get a gr
Neutrino physics is one of the fastest growing topic in phenomenological high energy physics. Neutrinos are elementary neutral particles and participate only in the weak interactions. For this reason it is very difficult to detect them experimentally. Nevertheless, much experimental progress has been obtained in the recent years. In particular our knowledge of the neutrino masses and mixing angles
This chapter investigates the tension between mass production and individual well-being, and how the actors who have positioned themselves in this market attract customers and meet their needs. In order to approach these questions, it is grounded in empirical material gathered from two specific spas and the cultural context in which they operate: Varberg Kurort Hotel & Spa and Hasseludden Conf
Popular Abstract in Swedish Kemi finns överallt omkring oss, både i vår omgivning såväl som inuti oss. Vi kanske inte alltid tänker på det, men kemiska processer påverkar oss dagligen och är en förutsättning för vår existens. Det kanske därför inte är så konstigt att människan alltid varit intresserad och fascinerad av just kemi. Ämnet kemi används dock inte bara för att förstå kemiska processer iA considerable part of all chemistry in nature and in industry occurs in solvents. Sol- vents affect both the interactions and the reactions of the particles immersed in them. The work in this thesis concerns the properties of ionic and polar solvents, as well as the interactions between solutes and/or dispersed particles. Molecular simulations and simple approximate theories were used to study th
