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Background: Even before the onset of age-related diseases, obesity might be a contributing factor to the cumulative burden of oxidative stress and chronic inflammation throughout the life course. Obesity may therefore contribute to accelerated shortening of telomeres. Consequently, obese persons are more likely to have shorter telomeres, but the association between body mass index (BMI) and leukoc
BACKGROUND: The Genetics of Subsequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD. METHODS: The consortium currently includes 57 studies from 18 countries, recruiting 185 614 participants with either acute coronary syndrome, stable CHD
Background The mortality in individuals with a family history of heart failure (HF) has not been determined. This nationwide sib-pair study aimed to determine mortality in individuals with a sibling affected with HF. Methods Sib-pairs were linked using the Swedish Multi-Generation Register, the Hospital Discharge Register and the Cause of Death Register for the period 1987–2012. Families with card
BackgroundIn pediatric patients, computed tomography (CT) is important in the medical chain of diagnosing and monitoring various diseases. Because children are more radiosensitive than adults, they require minimal radiation exposure. One way to achieve this goal is to implement new technical solutions, like iterative reconstruction.PurposeTo evaluate the potential of a new, iterative, model-based
The method presented in this paper is invented to address the problem of episodic memory in participants with highly restricted verbal abilities, 15-month-olds in this case. Here, we refer to episodic memory defined as a mind/brain system with three main responsibilities: to encode, to store and to recall individual memories. Episodic memory system requires three additional capacities, which make
The aim of the study was to assess possible relationships between adipocyte fatty acid-binding protein (FABP4) and total body fat (TBF), abdominal fat, body fat distribution, aerobic fitness, blood pressure, cardiac dimensions and the increase in body fat over 2 years in a community sample of children. A cross-sectional study was used in a community sample of 170 (92 boys and 78 girls) children ag
Purpose: The aim of this study was to develop a deep learning-based method for segmentation of bones in CT scans and test its accuracy compared to manual delineation, as a first step in the creation of an automated PET/CT-based method for quantifying skeletal tumour burden. Methods: Convolutional neural networks (CNNs) were trained to segme
Generation of 15 monoclonal antibodies (MAbs) allowed construction of epitope maps and specific two-site immunofluorometric assays for free prostate-specific antigen (PSA) and PSA complexed with alpha 1-antichymotrypsin (ACT). Close correlation of PSA concentrations obtained with the use of different assays of free PSA suggested extensive similarity in immunodetection of free PSA in serum. Assays
Anorexia nervosa is associated with bone loss during adulthood, but may also delay skeletal growth and mineral accrual during growth. We asked the following questions. 1) Is anorexia nervosa associated with reduced bone size and reduced volumetric bone mineral density (vBMD)? 2) Is estrogen replacement therapy (ERT) or recovery from anorexia nervosa associated with normal bone size and vBMD? Using
Denna uppsats undersöker gemenskapens uttryck och möjligheter i ett allt mer digitaliserat landskap. I takt med att allt fler relationer och kommunikationer förflyttas till den digitala sfären väcks frågor om vilka förutsättningar det sociala sammanhanget har där. Studien analyserar digitala funktioner och strukturers villkor och förutsättningar för sociala praktiker. Uppsatsen utgörs av en fallst
This essay analyzes the importance of music and dancing in Jane Austen's early novels. This is done by looking at a series of musical pastimes that were popular in the 18th century. The essay also provides an overlook of the musical period of the time.
This thesis examines the Oesch class schema in a Swedish context, and tests its ability to unveil cleavages in political preferences. The Oesch class schema operationalizes class by profession. It adds horizontal divisions based on different work logics to the vertical divisions which schemata such as ESEC build on. Two cleavages are thus captured, an economic (left-right) and a sociocultural (lib
Titel Försäljningskanalernas roll för varumärkeskapitalet – en kvantitativ studie om modeföretags val av försäljningskanaler Seminariedatum 2013-06-05 Ämne/Kurs FEKH29 Företagsekonomi: Examensarbete i marknadsföring på kandidatnivå, 15 högskolepoäng Författare Carolina Laurén, David Nilsson & Maria Rangin Handledare Clara Gustafsson Nyckelord Varumärkeskapital, Brand Resonance MoTitle The sales channels role of brand equity - a quantitative study of the fashion companies choice of sales channels Seminar date 2013-06-05 Course FEKH29 Business Administration: Degree Project in Marketing, Undergraduate Level, 15 University Credits Points (ECTS) Authors Carolina Laurén, David Nilsson, Maria Rangin Advisor Clara Gustafsson Key words Brand Equity, Brand Resonance Mo
The present study examined the relationship between perceived speechtime, therapeutic alliance, and gender in couples therapy. The aim was to investigate if there were any gender differences in therapeutic alliance and if male clients needed to rate themselves as having more perceived speech-time than female clients in order to remain in therapy. A quantitative method was used as well as questionn
Option valuation is typically done under the unrealistic assumption of perfect knowledge about model parameters. This thesis shows that risk-neutral valuation, while still adressing the parameter uncertainty, can be computed for a variety of models within the Fourier framework. This results in a computationally inexpensive method for valuating options. A study of S&P500 index option data shows
Populärkulturen spelar en viktig roll i att forma föreställningar om romantiska relationer, kärlek och intimitet. Denna uppsats syftar till att undersöka hur filmen “Fifty Shades of Grey” romantiserar makt och kontroll genom sina visuella och narrativa uttryck. Studien ägnar särskild uppmärksamhet åt hur kontroll legitimeras och hur könsroller representeras i relationen mellan de två protagonister
Bacteria and fungi, representing two major soil microorganism groups, play an important role in global nutrient biogeochemistry. Biogeographic patterns of bacterial and fungal biomass are of fundamental importance for mechanistically understanding nutrient cycling. We synthesized 1323 data points of phospholipid fatty acid-derived fungal biomass C (FBC), bacterial biomass C (BBC), and fungi:bacter
The in vivo fate of mesenchymal stromal cells (MSCs), including their clearance, interaction with host tissues, and persistence, remains incompletely understood following systemic or local clinical administration to patients. Although immune-mediated clearance mechanisms, such as triggering of the instant blood-mediated inflammatory reaction, activation of coagulation and complement pathways, apop
