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BACKGROUND: Social epidemiology investigates both individuals and their collectives. While the limits that define the individual bodies are very apparent, the collective body's geographical or cultural limits (e.g., "neighbourhood") are more difficult to discern. Also, epidemiologists normally investigate causation as changes in group means. However, many variables of interest in epidemiology may

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Dermatan sulfate is a highly sulfated polysaccharide and has a variety of biological functions in development and disease. Iduronic acid domains in dermatan sulfate, which are formed by the action of two DS-epimerases, have a key role in mediating these functions. We have identified the catalytic site and three putative catalytic residues in DS-epimerase 1, His205, Tyr261 and His450, by tertiary s

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The question of subgroups in eating disorders was addressed in this study. According to the DSM-IV manual, the two subtypes for anorexia nervosa are restricting and binge-eating/purging. For bulimia nervosa, the subtypes are purging and non-purging. An attempt was made here to examine alternative ways to create meaningful subgroups in the eating disordered patient group. A cluster analysis was per

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Background: The link between colorectal cancer (CRC) and type 2 diabetes mellitus (T2D) has been extensively studied. Although it is commonly accepted that T2D is a risk factor for CRC, the underlying mechanisms are still poorly understood. Research Design and Methods:Given that the genetic background contributes to both traits, it is conceivable that genetic variants associated with T2D may also

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Radiative lifetimes of nine levels in Eu II (4f(7)6p, 4f(6)5d6s and 4f(6)5d(2)) and Eu III (4f(6)5d) have been measured using time-resolved laser-induced fluorescence spectroscopy on a laser-produced europium plasma. Oscillator strengths for a number of Eu II lines have been derived by combining the lifetimes with branching ratios measured in the emission spectrum of a hollow-cathode lamp.

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BACKGROUND: Tumor development requires angiogenesis, and antiangiogenesis has been introduced in the treatment of cancer patients; however, how the cardiovascular phenotype correlates with cancer risk remains ill-defined. Here, we hypothesized that vasoactive peptides previously implicated in angiogenesis regulation predict long-term cancer risk.METHODS: We measured midregional proatrial natriuret

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Popular Abstract in Swedish Hormonerna vasopressin och oxytocin frisätts från hypofysens baklob. Hypofysen är en körtel, som är belägen på undersidan av hjärnan och utsöndrar en rad olika hormoner vilka i sin tur påverkar och reglerar aktiviteten i en mängd andra organ. Vasopressin medverkar till regleringen av vatten- och saltbalansen i kroppen, men verkar också sammandragande på icke-viljestyrdVasopressin and oxytocin seem to have pivotal roles in the pathophysiology of primary dysmenorrhoea and preterm labour. Prostaglandins are also involved in the regulation of uterine activity with different receptors mediating both stimulation and relaxation. We explored different aspects of synthesis, release and receptor pharmacology of vasopressin and oxytocin. We also tested a vasopressin and o

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In their natural habitats, bacteria and plants can be exposed to abiotic stresses such as drought, high salt concentrations and freezing, which are factors limiting their capacity for growth and proliferation. To withstand environmental stresses, they have evolved specific stress responses. These responses include physiological adaptations, alterations in gene expression and production of protecti

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Popular Abstract in Swedish Balans i vardagens sysslor - en förutsättning för kvinnors hälsa. Psykisk sjukdom och stress anges ofta som orsak till längre sjukskrivning och drabbar kvinnor till övervägande del. Majoriteten av Sveriges kvinnor är idag yrkesarbetande, de tar större ansvar för hem och familj, de arbetar oftare deltid, tar oftare ut ledighet för vård av sjuka barn och utför 65 % mer hThis thesis investigated the concept of balance in daily occupations. The overarching aim was to explore women’s patterns of everyday occupations and to investigate relationships between different aspects of patterns of daily occupations and health and well-being. The participants were working, cohabitant women with pre-school children. The methods used focused on exploring patterns of daily occup

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Popular Abstract in Swedish Vilken musiksmak har blodceller? Forskningen som presenteras i denna avhandling undersöker och drar nytta av hur olika celler uppför sig när de utsätts för ljud. På samma sätt som människor uppskattar olika sorters musik så reagerar olika typer av celler annorlunda beroende på vilka ljud de utsätts för. Cellerna är dessutom ganska konservativa. När de utsätts för ett vOver the last decades the ongoing work in the fields of Lab-on-a-Chip and Micro-Total-Analysis-Systems has led to the discovery of new or improved ways to handle and analyse small volumes of biofluids and complex biosuspensions. The benefits of working on the microscale include: miniaturization of the analysis systems with less need for large sample volumes; temporal and spatial control of suspend

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Popular Abstract in Swedish Bakgrund Effekterna av en behandling vid lungsjukdomar såsom KOL (KOL = kroniskt obstruktiv lungsjukdom) och astma kan utvärderas på olika sätt och objektiva mätmetoder såsom lungfunktion används vanligen som mått på utfallet. Metoder som är rapporterade direkt av patienter är numera benämnda “Patient-reported outcome” (PRO) och är ett samlingsbegrepp för alla subjektivBackground - The effects of intervention can be evaluated in different ways, and objective measurements of changes in lung function are commonly used as the outcome measure. Patient-reported outcome (PRO) is an umbrella term used for all patient-based assessments. One important PRO is health-related quality of life (HRQL), which may be used as an evaluative or discriminative measure. Objectives -

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The article investigates conceptions of freemasonry and civil society in the eighteenth century periodical Journal für Freymaurer (1784-1786).

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Product gas obtained through biomass gasification can be upgraded to hydrogen-rich synthesis gas. The synthesis gas can be further converted to liquid or gaseous fuels. However, the raw product gas contains both gas- and particle-phase impurities that can negatively affect both catalysts and hot-gas filters used for upgrading and cleaning. The present study aimed to characterize, both physically a