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Among different lipid nanoparticle systems, sponge-phase nanoparticles (SPNPs) have recently attracted interest due to their ability to encapsulate large macromolecules along with demonstrated high interfacial activity. The potential application of SPNPs calls for investigations into how buffer conditions affect SPNP structure and interfacial activity. Herein, we systematically investigated how di

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Popular Abstract in Swedish Populärvetenskaplig sammanfattning Inflammation i struphuvudet kan bero på annat än reflux Bakre laryngit är en form av kronisk inflammation som påverkar struphuvudets bakre del och ibland stämbanden samt ingången till matstrupen. Det kan ge upphov till symtom i form av hosta, heshet, ökad slembildning och klumpkänsla i halsen. Inflammationen kan orsakas av flera olika Posterior laryngitis (PL) is defined as an inflammation involving the posterior part of the glottal region in conjunction with symptoms. The cause is multifactorial. The aims of the work presented in this thesis were to examine symptoms, physical signs, different aetiologies and health-related quality of life (HRQOL) in patients with PL and/or oesophageal dysmotility. In paper I, a group of pati

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Loss of biodiversity in European farmland has been attributed to agricultural intensification and the resulting loss of ecological heterogeneity. To alleviate the effect of agricultural intensification, farmers are compensated via agri-environment schemes for carrying out farming in ways to preserve and restore biodiversity. However, the effectiveness of these schemes has been questioned and evalu

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The aim of this paper is to provide an explanation to why the degree of informal employment may vary substantially between different regions within a country. In Brazil, 45% of workers in the urban labor force are employed informally. The degree of informal employment, however, varies substantially across regions, with some cities having 20% and others having 80% or more of their labor force in th

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The disaccharide trehalose stabilizes proteins against unfolding, but the underlying mechanism is not well understood. Because trehalose is preferentially excluded from the protein surface, it is of interest to examine how trehalose modifies the structure and dynamics of the solvent. From the spin relaxation rates of deuterated trehalose and (17)O-enriched water, we obtain the rotational dynamics

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The metabolic syndrome is a clustering of several risk factors associated with diabetes and cardiovascular disease. Diabetes is a global problem with 90% of patients suffering from type 2 diabetes (T2D), which is attributable to various factors including genetic predispositions and lifestyle. In T2D, there is a reduction in β cell mass and function, and impaired glucose homeostasis. It is often as

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Antimicrobial peptides represent a heterogeneous group that displays multiple modes of action such as bacteriostatic, microbicidal and cytolytic properties that are sequence and concentration dependent. Life threatening infectious disease is now a worldwide crisis and treating them effectively is becoming difficult day by day, due to the emergence of antibiotic resistant strains at alarming rates.

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Syfte och frågeställning: Internet har vuxit och dess användningsfrekvens har ökat enormt under den sista delen av 1990-talet fram till idag. Detta har resulterat till att Internet har blivit en central kommunikationskanal för den västerländska befolkningen. För företag och organisationer har Internet även blivit en viktig marknadsföringskanal. Internetannonsering blir ett allt vanligare företeels

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En sammanfattning av uppsatsen på maximalt 8000 tecken.

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We study an extended bootstrap percolation process in several steps in dimension one, assuming noncyclic boundary conditions. We study the asymptotic behavior of the process as the size of the underlying graph goes to innity. We nd a phase transition with respect to the initial conditions. The phase diagram on the set of initial conditionals of the extended process is described completely. This pr

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We investigate the properties of multifractal products of the exponential of stationary diffusion processes defined by stochastic differential equations with linear drift and certain form of the diffusion coefficient corresponding to a variety of marginal distribution.

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This study has determined the fracture mechanical properties of 9 types of rock, namely fine-, medium- and coarse-grained granites, gneiss, quartzite, diabase, gabbro, and fine- and coarse-grained limestones. Test results show among other things that quartzite has the highest compressive strength and fracture energy, while diabase has the highest splitting tensile strength and modulus of elasticit

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The photodissociation dynamics of CH2ICH2I, CF2ICF2I, and CF2BrCF2I have been studied in solution after excitation at 266 nm. Formation of I-2 is apparent within tens of picoseconds in solutions of CH2ICH2I and CF2ICF2I in acetonitrile. but not from CF2BrCF2I, More I-2 is formed from CH2ICH2I rather than from CF2-ICF2I, as expected if the 12 formation is a result of secondary dissociation of the h

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A method for simultaneous determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in urine is described. These compounds are metabolites of N-methyl-2-pyrrolidone, a powerful and widely used organic solvent. 5-Hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide were purified from urine by adsorption to a C8 solid-phase extraction column and then elution by ethyl