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The first part of the thesis aims to investigate the applicability of JGrafchart and its associated Model of Computation(MoC) for describing sequential control in aircraft primary power distribution systems. The motivation behind this is the need for better modeling tools and in particular support for separation between nominal control and fault handling. Also, as system complexity increases, bett
This master thesis describes how to compensate for the compliance of the Gantry-Tau robot. The main reason for this is to improve the performance of the robot. The compliance is modeled as nine springs, one for each cart and each link. The model seems promising but has only been tested in homing position of the robot but shows a positive result in decreasing the compliance. External control of the
The complexity with which modern science develops and drives the scientific community to reorganise makes it important to analyse what organisational forms research activity takes and why. Collaboration becomes a flexible arrangement designed to meet scientific challenges by scientists and non-scientists in common. It is increasingly recognised to be the best, or even perhaps the only way of achie
For many years the benefits of using stockings that exert a pressure on the legs, to prevent and treat a number of health conditions, have been well known. For just as many years carers and caretakers have been struggling to put on these stockings onto the legs. The high compression strength of the stockings makes it very difficult to put them on the way one does with ordinary stockings. Today, me
In this project, the several steps in a product development process can be followed, from the first brainstorming of basic concepts to the final implementation of the manufactured product in the factory. The project was assigned by Faiveley Transport Nordic AB and its aim was to design a well functioning test rig for testing of their train brake units. The new rig’s advantages compared to old exi
Aim of this study is to explore the term normalization as a social process that shifts the level of tolerance in societies through examination of the association between cannabis usage as daily life leisure activity and the growing tolerance of this substance use. Contemporary studies suggest that consumption and usage of cannabis should be examined as any other social processes, which are unavoid
The interaction of antikaons (K) with nucleons and nuclei in the low-energy regime represents a very active research field in hadron physics. A unique and rather direct experimental access to the antikaon-nucleon scattering lengths is provided by precision X-ray spectroscopy of transitions in low-lying states in the lightest kaonic atoms (i.e. kaonic hydrogen and deuterium). In the SIDDHARTA exper
Neuropeptide Y (NPY-(1-36)) acts on Y1 and Y2 receptors at the sympathetic neuroeffector junction. Various truncated NPY analogs were tested in the isolated guinea-pig caval vein where NPY is a vasoconstrictor (Y1 receptors) and in isolated rat vas deferens, by monitoring the suppression of electrically evoked contractions (Y2 receptors). The aim of this study was to define which parts of the NPY-
The water use associated with electricity generation and consumption has been the focus of research for decades. This study provides an overview of the water–electricity nexus from the perspectives of electricity production and consumption. In terms of production, the electricity generation and associated water use for various regions are summarized and compared. The spatial mismatch between water
Biobjective and bidisciplinary optimal design of high-performance airfoil and wing applying two kinds of optimization methods and genetic algorithm are discussed. An objective function combination method (OFCM) of constructing a resultant objective function in DOM or a fitness function in GA for biobjective optimization.
Not only has recombinant DNA added another source of insulin for treatment, but also, and perhaps more important, it has allowed the development of new techniques for studying the structure and function of the B cell at the gene level. We can only hope that this information will bring us closer to the understanding of the disease, so the diabetic patient may benefit from other measures of treatmen
A model based on rate-equation analysis has been developed for simulation of two-photon-excited laser-induced fluorescence of carbon monoxide (CO) in the Hopfield-Birge band at 230 nm. The model has been compared with experimental fluorescence profiles measured along focused beams provided by lasers emitting nano-, pico-, and femtosecond pulses. Good quantitative agreement was obtained between sim
To elucidate the role of biogenic amines in insulin secretion, pancreatic islets rich in β-cells were microdissected from obese-hyperglycemic mice and were incubated with 14C-labelled 5-hydroxytryptamine (5-HT). The saturability of uptake and the fact that 5-HT was accumulated to high levels indicated that the β-cells possess a transport system with great capacity for this amine. The initial uptak
Background: Early-onset pancreatic cancer (< 50 years, EOPC) is uncommon and limited data exist on clinical presentation and long-term survival. The aim of this study was to compare outcomes between patients with EOPC and those with later-onset pancreatic cancer (≥ 50 years, LOPC) using a large population-based cohort. Methods: The Surveillance, Epidemiology, and End Results (SEER) database was qu
Proteinase activated receptor-2 plays a crucial role in a wide variety of conditions with a strong inflammatory component. We present the discovery and characterization of two structurally different, potent, selective, and metabolically stable small-molecule PAR-2 agonists. These ligands may be useful as pharmacological tools for elucidating the complex physiological role of the PAR-2 receptors as
Recently, the geographical origins of Ashkenazic Jews (AJs) and their native language Yiddish were investigated by applying the Geographic Population Structure (GPS) to a cohort of exclusively Yiddish-speaking and multilingual AJs. GPS localized most AJs along major ancient trade routes in northeastern Turkey adjacent to primeval villages with names that resemble the word "Ashkenaz." These finding
This paper argues that an economic system of large and small technology-based firms which interact through technology-related acquisitions and spin-offs can be highly conducive to overall innovativeness and growth. Based on Williamson's (1975) suggestion of a 'systems solution by classical specialisation', and the empirical research on Swedish technology-based firms reported by Lindholm (1994), an
Soil organic matter (SOM) plays a significant role in the global carbon (C) and nutrients cycles, not only since SOM is a major storage reservoir of C and plant nutrients, but also since microbial decomposition of SOM releases large quantities of CO2 to the atmosphere. The accelerated or reduced turnover rate of SOM after the input of labile C compounds is a phenomenon known as the priming effect
Recent research has provided broad accounts of what high institutional quality is; bureaucrats should be impartial and recruited on merit, public power should not be used for private gain, there should be rule of law, and property rights should be secure. Many scholars argue the reason why, in spite of this knowledge, recent institutional reforms have had limited success is that improvements are n
