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This thesis examines whether implied volatility derived from Swedish equity options provides superior predictive information relative to historical volatility for future realized volatility and stock returns, and whether this information improves portfolio risk outcomes. Using monthly option and stock data for OMXS30 firms, the study applies predictive regressions and constructs minimum variance p
This thesis investigates probing antennas within a small shielded test enclosure for IoT, Internet of Things, products for the detection of manufacturing deviations. The small enclosure forces the transmitter and receiver to be in the near-field. Shielding of the enclosure additionally generates a multipath environment, which becomes sensitive to displacements of objects such as wires or metallic
Malaria is a well-known disease and affects large regions around the world. Medicines used for treatment already exist, but due to increasing resistance and unpleasant side effects it has become critical to develop new drug candidates. Several palladium complexes were synthesised and studied to understand their properties for treating malaria. The ligands and the complexes were synthesised and cha
Health applications have increasingly been used to improve physical, mental and social well-being. Chronic pain (CP) is defined as pain that lasts for a period of three months and causes sporadic or constant discomfort. In Portugal, the treatments for this type of pain are almost exclusively pharmacological and with known limited effects. Endowing patients with self-management skills, will help th
Derivatives of 3-ethyl-3-(hydroxymethyl)oxetane (trimethylolpropane oxetane), potentially useful in cationic UV-curable formulations, were prepared by the simple acid-catalyzed addition of alcohols to 1-alkenyl ethers. Examples include several difunctional oxetane derivatives along with one fluorinated and one acryloylated oxetane derivative. These new materials may find use as reactive diluents o
The stochastic behavior of FM-clicks in an unmodulated carrier plus noise is studied in terms of the conditional behavior of stationary Gaussian processes after level crossings. By a systematic use of thc Slepian model processes it is shown that the normalized shape of a positive FM-click approaches a certain rational function with simple random coefficients as the carrier-to-noise ratio tends to
Nuclear knockout reactions at relativistic energies provide a sensitive tool to determine the ground state properties of nuclei close to the drip line. Studies with kinematically complete measurements reveal the initial correlations in the reacting systems and yield spectroscopic information on the continuum states populated in the decay channel. The coincident data of charged fragments and neutro
Salt linkages, electrostatic effects, and modified water structure are important for the properties of gluten, wheat flour dough, and baking (Belitz et al 1986). These effects have been studied at various levels of salt concentration, pH, and ion strength (Doguchi and Hlynka 1967; Salovaara 1982; Kinsella and Hale 1984; Holmes and Hoseney 1987 Preston 1989; He et al 1992). Sodium chloride usually
Parkinson's disease is a devastating neurological condition that affects at least four million people. A striking feature of this disorder is the preferential loss of dopamine-producing neurons in the midbrain. Several aetiological triggers have been linked to Parkinson's disease, including genetic mutations and environmental toxins, but the pathway that leads to cell death is unknown. Recent deve
This introduction to the biology of standing waters integrates the effects of abiotic constraints and biotic interactions at both the population and community level, and examines how the distribution and success of different organisms in this freshwater habitat can be explained and predicted
Thermal stability of food-borne pathogens in apple cider is influenced by the composition of the product. As a preliminary step to determine the effect of pasteurization of apple cider on the survival of Escherichia coli O157:H7, a study was carried out to characterize apples and unpasteurized apple cider produced by a Guelph area orchard. Samples of commercial unpasteurized cider and the constitu
Popular Abstract in Swedish Pyrimidiner är DNA-byggstenar som är essentiella för cellens överlevnad och delning. I mänskliga celler finns pyrimidiner att tillgå antingen genom återupptag eller genom biosyntes (nysyntes). Biosyntesen av pyrimidiner sker i flera steg och i ett av dem spelar enzymet Dihydroorotat dehydrogenas (DHODH) en avgörande roll genom att katalysera en oxidationsreaktion. När cIn the first part of the PhD work, small chemical entities (fragments) found to inhibit human dihydroorotate dehydrogenase (DHODH), were chemically optimized. As part of an ample program at Active Biotech to find new drugs against autoimmune diseases, expanded fragments were repeatedly designed, synthesized and evaluated in a human DHODH assay. Potent inhibitors were identified within three classe
Would slightly better performance be significantly more valuable from a market perspective? Would significantly better performance be just slightly more expensive to implement? When dealing with quality requirements, we often end up in a difficult trade-off analysis. Aspects such as release targets, end-user experience, and business opportunities must be taken into consideration. But when is the q
In recent years, the International Maritime Organization agreed on aiming to reduce shipping's greenhouse gas emissions by 50% with respect to 2009 levels. Meanwhile, cruise ship tourism is growing at a fast pace, making the challenge of achieving this goal even harder. The complexity of the energy system of these ships makes them of particular interest from an energy systems perspective. To illus
