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The coding sequence of rat liver catechol-O-methyl-transferase (COMT; EC 2.1.1.6) was determined from rat cDNA and genomic libraries were screened with DNA probes and specific antiserum. The open reading frame consisted of 663 nucleotides coding for a 221-amino acid (aa) polypeptide with a deduced Mr of 24747. No obvious hydrophobic signal sequence, membrane-spanning domains, or potential N-glycos

Low-energy electron diffraction, scanning tunneling microscopy, and photoelectron spectroscopy results from the submonolayer Sm- and Yb-induced surface structures are presented. Several similar metal-induced surface reconstructions are found to exist for Yb and Sm on Si(111) for low submonolayer coverages: 3×2, 5×1, and 7×1. At higher submonolayer coverage, Yb induces a 2×1 reconstruction while Sm

The compressibility and thermal expansion of the cubic silicon nitride (c-Si3N4) phase have been investigated by performing in situ x-ray powder-diffraction measurements using synchrotron radiation, complemented with computer simulations by means of first-principles calculations. The bulk compressibility of the c-Si3N4 phase originates from the average of both Si-N tetrahedral and octahedral compr

This unique collection gathers together important instruments dealing with the relationship between business and a range of topics such as labour rights, security issues, environmental protection, anti-corruption, good governance, poverty alleviation and development, which all have important human rights dimensions. The premise for the collection is that business has both the responsibility and th

Geomagnetic and mineral magnetic data provide geological indices that are both independent of human impact (i.e. geomagnetic) and respond to human-induced environmental impact (i.e. mineral magnetic). We provide the first discussion of such magnetic events for help in defining the Anthropocene. Within the Holocene, a potential geomagnetic marker for the Anthropocene is the low dipole latitude at c

This thesis presents experimental investigation and modelling of the mechanical response of glassy polycarbonate (PC) during deformation. The mechanical response is studied experimentally over a wide range of length-scales using X-ray scattering techniques and optical full-field deformation measurement by Digital Image Correlation (DIC). Results from the experimental work have been used to develop

The title compound, [PdCl2(C11H9N)(C13H14N2)], represents a new class of palladium-based polymerizable monomer which could give a potentially catalytically active polymer. It was synthesized via transmetallation from the corresponding silver complex. The PdII ion coordinates two Cl anions, one C atom from the N-heterocyclic carbene (NHC) ligand and one N atom from the 4-phenylpyridine ligand, disp

In this work extensions to principal component analysis (PCA) for wastewater treatment (WWT) process monitoring are discussed. Conventional PCA has some limitations when used for WWT monitoring. Firstly, PCA assumes that data are stationary, which is normally not the case in WWT monitoring. Secondly, PCA is most suitable for monitoring data that display events in one time-scale. However, in WWT op

Minimal encephalopathy was originally associated with chronic liver disease but is increasingly associated with most other chronic diseases and particularly with diabetes and also chronic disorders in other organs: kidneys, lungs, thyroid and with obesity. It is increasingly with dramatically increased and more or less permanent increase in systemic inflammation, most likely a result of Western li

Embedded computer systems are subject to a multitude of requirements. These include real-time requirements, that is, such computers must respond to external events within limited time. Many systems, such as satellites and telephone switches, must also operate unattended for long periods of time. They must not fail due to defective software. Modern object-oriented programming languages, particular