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During the formation of peribronchial fibrosis in asthma, remodeling of connective tissue is due to an increase in deposition of extracellular matrix components like that of specific types of collagens and proteoglycans. By taking bronchial biopsies, we were able to isolate cell cultures derived from asthmatic patients and healthy volunteers, which provides a good model system to study differences
Two different dowel-type joints of differing size were loaded in tension parallel to the grain. The strain distribution in the joint area was studied using a contact-free measurement system. The results were compared with those of numerical analysis. The measurement system was found to be a valuable complement to traditional measurement techniques and also to numerical analyses performed in parame
A model of pleural fluid turnover, based on mass conservation law, was developed from experimental evidence that 1) pleural fluid filters through the parietal pleura and is drained by parietal lymphatics and 2) lymph flow increases after an increase in pleural liquid volume, attaining a maximum value 10 times greater than control. From the differential equation describing the time evolution of ple
Transfer of collagen type H (CH)-specific monoclonal antibodies induces an acute form of arthritis (collagen type H antibody-induced arthritis, CAIA) in nave mice. Arthritis was induced using a pair of monoclonal antibodies M2139 and CIIC1, binding to J1 and C1(I) epitopes of CH, respectively. Thereafter, lipopolysaccharide injection was used to increase the incidence and severity of the disease.
An outline of the activities and history of the Centre for European Studies at the University of Lund, Sweden.
Lean premixed dry low emission (DLE) combustion system in a gas turbine engine is a globally accepted concept to reduce pollutant emissions and to improve combustion efficiency. This study is focused on an industrial downscaled prototype burner (4th Generation Dry Low Emission Burner for SGT-750 designed and manufactured by Siemens Industrial Turbo machinery AB), which has been tested extensively
The aggregating proteoglycans of the lectican family are important components of extracellular matrices. Aggrecan is the most well studied of these and is central to cartilage biomechanical properties and skeletal development. Key to its biological function is the fixed charge of the many glycosaminoglycan chains, that provide the basis for the viscoelastic properties necessary for load distributi
Within recent years, there has been a renewed focus on sound in urban environments. From sound installations in public space to sound festivals in alternative settings, we find a common interest in sound art relating to the urban environment. Artworks or interventions presented in such contexts share the characteristics of site specificity. However, this article will consider the artwork in a broa
Identification and quantitative monitoring of mutant BCR-ABL1 subclones displaying resistance to tyrosine kinase inhibitors (TKIs) have become important tasks in patients with Ph-positive leukemias. Different technologies have been established for patient screening. Various next-generation sequencing (NGS) platforms facilitating sensitive detection and quantitative monitoring of mutations in the A
In the modern age of mediated visibility, media scandal is an immense risk that threatens to destroy the lives of people who have become the focus of public attention. The paper is concerned with the question of how the individual is affected by the attention when the media hype a story. Empirically, it is based upon in-depth interviews with Swedish persons who have been in the epicenter of scanda
