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Objective: Citrate is widely used in dialysis, either as an acid in dialysis fluids or as a regional anticoagulant. In both cases, the concentration of citrate in the plasma of the patients will increase above physiological levels, up to 5-foldes in some cases. The aim of this study was to investigate the effect of citrate on the transcriptional level, as well as on the metabolic level and elucida

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Världens sötvattensystemen är sårbara och har upplevt betydande miljöförändringar. Utöver direkt mänsklig påverkan, innebär klimatförändringar ytterligare påfrestningar på våra färskvattenresurser. I denna studie undersöks hur klimatförändringar har påverkat tidsperioden av istäckning i svenska sjöar och vattendrag. Observationer från över 750 sjöar och vattendrag i Sverige har analyserats, med viThe worlds freshwater systems are vulnerable and have experienced significant environmental changes. In addition to direct anthropogenic impacts, climate change poses yet another source of pressure on the freshwater resources. This study investigates climate change impacts on ice cover duration in Swedish lakes and rivers. In situ observations from over 750 lakes and rivers in Sweden were analyzed

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Sandvik Coromant is the market leader of producing tools for advanced metal cutting. The tools are produced in cemented carbide, however Sandvik Coromant does not produce tools for machining cemented carbide. The aim of the thesis was to perform cutting tests in cemented carbide with diamond tools to investigate if the binder content affected the machinability of the process. The wear tests were

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High-throughput screening is one of the most extensively used methods for the identification of molecules of interest during early stages of drug development projects. It is however subject to many artifacts due to various mechanisms. Aggregation and redox cycling are examples of mechanisms of unspecific inhibition that make a large number of compounds appear as active in several high throughput s

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Even though protonemal development of bryophytes has been well studied, it remains unknown whether interspecific competition among mosses species affects their early growth and development. This study evaluated the effects of interspecific competition on in vitro germination and gametophyte development between each pair-wise combination from six common moss species: Atrichum undulatum, Bryum argen

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Abstract: The gender pay-gap is not a new phenomenon in Brazil. Since the increase of female participation on the labor market, the gap has remained a persistent problem that has generated a wide range of studies on the topic. The Human Capital Theory argues that individuals’ education and on-the-job experience are essential determinants on wage estimations. This assessment is not disputed in the

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The all-sky survey of Gaia will generate vast amounts of astrometric data, in which there are expected to be thousands of planets found. Finding a system of $n_\textup{p}$ planets requires fitting of a total $5+7n_\textup{p}$ parameters: five astrometric and seven Keplerian parameters for every planet. The problem is thus highly non-linear and computationally prohibitive. After exploiting the line

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HVAC systems are widely used to provide a good indoor air quality in buildings. Buildings stand for a substantial part of the total energy consumption in developed countries, and with an increased focus on cost reductions and energy savings, it is necessary to use intelligent and energy-efficient controllers. Accurate models describing the dynamics of the building system is a good basis for intel

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This master thesis is on Statistical Process Control (SPC). The objective is to evaluate if SPC can be used in a process that produces plates for heat exchanger, the process evaluated is located at Alfa Laval Lund AB. The products are produced in the process by punching and shearing metal coils. An ambition in the project is also to increase the knowledge about Statistical Process Control at Alfa

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Cardiovascular diseases are accountable for almost 50 % of the mortality number in Europe which is why research on its causes is highly prioritised. For practical and ethical reasons, in vitro study models are of high importance to enable research on cardiac abnormal behaviours. To meet this issue, researchers from Imec, Belgium, developed Neuray-II, the second generation of a biocompatible chip w

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This report is the result of a masters project conducted at the Division of Structural Mechanics at Lund University. The purpose of the project was to integrate a FEM mesh generator with the Python version of the code library CALFEM and improve the mesh visualisation capabilities of said library. This report describes how the mesher software Gmsh and the visualisation library visvis were integrate

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The main purpose of this explorative master thesis is to describe, explain and understand the main success factors that lie behind the regional innovation system in Silicon Wadi in Israel. This is done in order to suggest some tentative ideas on how to further develop the emerging ICT cluster in Malmö/Lund. Four sub purposes have been applied in order to achieve the main purpose: To understand why

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Det allmänna preferenssystemet GSP är ett av EU: s viktigaste unilaterala handelsavtal som ingås med utvecklingsländer. För att gynnas av behandlingen måste länderna uppfylla särskilda kriterier. Ett av villkoren är ratificering och effektiv implementering av ett antal internationella konventioner om mänskliga rättigheter. Bland dessa ingår Internationella arbetsorganisationens (ILO) internationelThe Generalised Scheme of Preferences (GSP) is one of the EU’s most important unilateral trade measures which grants tariff preferences to developing countries. In order to receive this preferential treatment countries are required to fulfil specific criteria. One of the conditions is the ratification and effective implementation of a number of international human rights conventions. Among these,

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This paper empirically investigates the relationship between product market competition and innovation in seven European countries for the period 1987-2006. To approximate change in competition level three measures are considered: mark-up level, import penetration and the number of firms on the market. Innovation is measured as R&D intensity. The analysis shows that effect of product market co

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High-spin oxoiron(IV) complexes are often postulated as intermediates in the catalytic cycle of nonheme iron oxygenases. Their C−H bond cleaving ability is attributed to the highly reactive quintet (S = 2) spin state. However, as of today, there are very few synthetic complexes that enforce the high spin state and even fewer that retain a high reactivity. In this study, a new tripodal tetradentat

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Simulation studies are today an important tool in the development of new networks. For this purpose the NS-3 network simulator can be used. The focus of this thesis work lies on 802.11ac, the latest version of the Wi-Fi standard. NS-3 does not support the IEEE 802.11ac standard and the goal was to implement features for this. Different deployment scenarios were modeled in various conditions and th

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This thesis concerns steady state equations of mass action systems and methods for solving them symbolically in Matlab. We study two different methods for solving such systems with slightly different applicability. One that is fast but limited, the other one is slower but more general. We also study the question of parameter dependence of solutions and model reduction. The parameter dependence

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The Common Agricultural Policy is one of the most important policies within the European Union. However, the support from CAP have had some unexpected consequences for the environment. Major changes were made in 2003 regarding the way payments were given to farmers, in order to reduce the environmental impact of agricultural production. The support was made decoupled, which basically meant a great