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Malaria is a life-threatening disease, but widespread antimalarial drug resistance has become a major obstacle when it comes to malaria treatment. Derivatives of existing drugs are potential drug candidates that can overcome this resistance and in recent years metal derivatives of chloroquine (CQ) have been of interest for their potential antimalarial activity. Three new organometallic complexes o
Background: In today’s business climate, companies need to make sure they have efficient resource management and that the quality of product and services fulfills the customers constant changing expectations, potential regulations, and global environmental policies. Possible approaches for companies to address this is through more strategic purchasing and earlier involvement of purchasers in proc
We utilize data from the Survey of Health, Ageing and Retirement in Europe (SHARE) 1 to investigate the impact of retirement on mental health in a multi-country setting. To deal with endogeneity in retirement behaviour, we employ an individual-fixed effects IV strategy where pension eligibility thresholds at which financial incentives to retire are exploited to predict retirement behaviour. The co
Cancer is a disease affecting many people where a possible treatment is immunotherapy. Immunotherapy has possible side effects called immune-related adverse events (irAEs) where cytokine release syndrome (CRS) is one. CRS differs in severity and an increased amount of cytokines are secreted. In this project, the aim was to explore key events of irAEs and to develop an assay to predict CRS. The eff
Dark Academia är en av flertalet digitala subkulturer som uppkommit på sociala medier under senare år. Bilder och videor föreställande akademiska sammanhang, klassisk litteratur, och stilguider i en mörkare färgskala är typexempel på sådant som kan visas i relation till estetiken. Genom ett kartläggande av estetikens bildliga uttryck på forumet Pinterest undersöker denna uppsats hur dessa uttryck
Farm size expansion in some countries in Sub-Saharan Africa, including in Ghana, is a recent phenomenon, and is indicative of the agricultural transformation process taking place in the region. Technology use and adoption level is an integral and complex part of this process, which is studied in relation to the expanding farm sizes and agricultural transformation in this study. It follows an explo
Organizational change due to digitalization trends puts established organizations under pressure to constantly adapt in order to compete in today’s markets. The disruptive nature of such transformational changes significantly impacts what organizations stand for and, thus, how organizational members relate to their organization. Taking an interpretivist stance, the aim of this study is to understa
HIV is the world’s leading infectious killer and young people constitute a large part of those who are infected. Preventative interventions directed to young people often fail to provide the comprehensive information about HIV/AIDS that the young people need and the information given is not always accurately understood. The aim of this study was to explore adolescents’ comprehension regarding HIV/
Bangladesh is the most densely populated country in the world with a high poverty rate. It is a man's country and the women are highly disadvantaged in all areas. It is concluded that gender discrimination has a negative impact on women’s reproductive and mental health. In Bangladesh the work of non governmental organisations has improved women's access to social organisations and networks
Childhood malnutrition is a considerable health problem in developing countries. The study took place in Kerala, India. The aim of the study was to describe the communication between nurses and mothers concerning prevention of child-malnutrition, in aspects of how this communication was carried out and what information was given. A qualitative study was performed with unstructured interviews and p
The following research explores a critical intersection between the work of mine action and the climate. It addresses the amplified impacts of climate change on water in Yemen, a country afflicted by protracted conflict and growing climate threats. This study showcases the necessity of integrating climate considerations into the mine action strategies and underpins the impact of climate change on
Abstract Author: Dana Štěpánková Title: Breaking the Stereotypes: Exploring Control and Self-Expression of ModernDay Freak Show Performers Supervisor: Sébastien Tutenges Master’s Thesis SOCM04, Cultural Criminology, 30 credits Department of Sociology, Spring 2023 Freak shows have been historically depicted as dehumanizing spectacles exhibiting individuals with physical anomalies. Over time, these
The aim of the project is to develop a framework for an insurance policy for digital assets. The project comprised several stages, starting with the identification of risks associated with these assets. Policyholders were then categorized into two groups based on a predefined rating factor. Subsequently, data about previous thefts was gathered, two different approaches were explored. In the first
This study explored the importance of short-chain fatty acids (SCFAs) in maintaining gut health and how different diets affect their levels. Blood plasma and serum samples from mice subjected to two intervention studies on oats and fruits were analysed to determine SCFA concentrations. Using a one-way ANOVA, the study compared SCFA levels in five different diet groups focused on fruit supplementa
Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma with poor response to generalized treatment regimens. Tools for stratifying patients based on molecular profiles of the tumor, such as the expression level of a biomarker, are needed to enable more targeted therapies. A potential biomarker for MCL patient stratification is the surface protein CD25. This study aimed to assess the frequency
Malaria is one of the most widespread and life-threatening infectious diseases in the world and is caused by parasites from the genus Plasmodium, transmitted to humans through mosquito bites. Despite great progress in the development of antimalarial drugs, the growing resistance to them, especially chloroquine, is a major problem. New drugs therefore need to be developed and chloroquine analogues
Den ökande andelen variabla förnybara energikällor i det svenska elsystemet har medfört ett växande behov av flexibilitet och balanstjänster. Batterienergilagringssystem betraktas som en nyckelteknik för att möta dessa behov, men deras ekonomiska lönsamhet är i hög grad beroende av marknadens utformning, geografisk placering samt vald operativ strategi. Syftet med detta examensarbete är att analysThe increasing share of variable renewable energy sources in the Swedish power system has led to growing demand for flexibility and balancing services. Battery energy storage systems (BESS) are widely regarded as a key technology to meet these needs, yet their economic viability depends strongly on market design, geographical location, and operational strategy. This thesis assesses the revenue pot
Linear regression is a standard tool for numerical prediction, but there are several estimators to choose from, and this choice can greatly affect prediction accuracy. This thesis empirically explores how the out-of-sample predictive performance of ordinary least squares (OLS), ridge regression (Ridge), and the lasso (Lasso) is affected by varying key model conditions, given a baseline setting. Fo
I denna fallstudie kommer det virala sociala mediefenomenet “Get Ready With Me” (GRWM) att utforskas. Genom en kvalitativ innehållsanalys har vi analyserat detta fenomen, för att kunna redogöra för hur Get Ready With Me-videor främjar ett inkluderat flickskap samt formar unga tjejers identiteter. Vårt analyserade material består av olika kreatörers Get Ready With Me-videor från plattformen TikTok.
