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Objective: To determine the incidence and clinical significance of neutralizing antibody (NAb) formation in patients with relapsing multiple sclerosis ( MS) who participated in the European Interferon Beta-1a IM Dose-Comparison Study. Methods. Patients were randomized to treatment with interferon beta-1a (IFN beta-1a) 30 mu g or 60 mu g IM once weekly for up to 4 years. Serum samples obtained at b
Foraging strategies, the cost-benefit associated with the search for new resources, have only begun to be explored in arbuscular mycorrhizal fungi (AMF). We show the use of C-13-labelling, via shoot photosynthesis, of the 16: 1omega5 fatty acid biomarker (the dominant and rather specific fatty acid in AMF storage lipids) to study the immediate patterns of carbon allocation to fungal lipids in resp
The evaporative gas turbine (EvGT) pilot plant has been in operation at Lund University in Sweden since 1997. This project has led to improved knowledge of evaporative techniques and the concept of introducing fuel into gas turbines by evaporation. This results in, amongst others, power augmentation, efficiency increase and lower emissions. This article presents the experimental and theoretical re
The thesis is focused on an attempt to delay photoreceptor cell death in the rd1 mouse using Lens Epithelium Derived Growth Factor (LEDGF), Glutathione S-Transferase mu (GST-?? and Glutathione S-Transferase alpha (GST-?? in an organ culture paradigm as well as the role of metalloproteases (MMPs) and their tissue inhibitors in photoreceptor degeneration (TIMPs). The rd1 mouse model displays a reti
The Swedish government decided in 1994, as part of the so-called 50,000 Swedish crowns scheme, to set aside a portion of the labour market budget for the further training and retraining of local government and country council employees. The present article reports on the experiences of the training effort that took place in 1994–1995 and provides a theoretical framework for discussing staff traini
An evaluation and review of a structurally related group of fragrance materials.
Popular Abstract in Swedish Baserat på ett nytt data material bestående av observationer på 16 variabler i 232 val i Afrika, görs tre olika analyser. Först avvisas ett antal etablerade hypoteser om nutida Afrikansk politik och demokratisering. Sedan påvisas valens självförstärkande och självförbättrande kraft med hänvisning till institutioners interna logik och strukturering av aktörers incitamenThis book is about elections and democracy in newly democratizing countries. Building on a new data set of 5,568 observations in 232 elections, it provides evidence elections have a casual impact on improving the quality of democracy in Africa in more than one way. The study demonstrates multiparty elections do not signal the end of transitions to democracy but rather foster liberalization and hav
Optical region spectra of 31 HgMn stars have been studied for the abundance and isotope mixture of mercury. In the course of the investigation the lines Hg I lambda 4358 and Hg Ii lambda lambda3984,6149 have been studied, with abundances established for all three lines in several HgMn stars. The mercury isotope mixture has been determined from high resolution spectra of the lambda 3984 line.Possib
The middle Cambrian -Furongian transitional interval was a time of significant biotic and environmental changes. Strata of this age in Scania, southern Sweden, contain two interlayered biofacies, a normal one dominated by trilobites and an anomalous one dominated by phosphatocopines (small bivalved arthropods). In places these biofacies are separated by intervals barren of fossils. In a phosphatoc
Bacillus subtilis YtlP is a protein that is predicted to belong to the bacterial and archael 2'-5' RNA-ligase family. It contains 183 residues and two copies of the HXTX sequence motif conserved among proteins belonging to this family. In order to determine the structure of YtlP and to compare it with the paralogue YjcG and identified 2'-5' RNA ligases, the gene ytlP was amplified from B. subtilis
Discussions about values are common in many contexts. Often, what is debated is the choice of means to realize or protect various values, but sometimes the discussion concerns the very values that ought to be realized or protected. Philosophical debate in this area has mainly been focused on two kinds of issues. Philosophers have tried to identify the set of fundamental values, i.e., to provide wh
We calculate the one-loop effective action of the SU(2) Yang-Mills theory for center-vortex configurations, both in 3D and 4D. We find that in both cases there are minima of the effective action, corresponding to vortices of the transverse size approximately 4/g(3)(2) and 1.7/Lambda((MS) over bar), respectively. The values of the effective actions at the minima are negative, suggesting that the Eu
Sulfate adsorption was implemented in the dynamic, multi-layer soil chemistry model SAFE. The process is modeled by an isotherm in which sulfate adsorption is considered to be fully reversible and dependent on sulfate concentration as well as pH in soil solution. The isotherm was parameterized by a site-specific series of simple batch experiments at different pH (3.8–5.0) and sulfate concentration
Popular Abstract in Swedish Numeriska methoder har används för att beräkna turbulent strömning och värmeöverföring i komplexa kanaler med olika turbulens modeller.Th need for a reliable and reasonable accurate turbulence model without specific convergence problem for calculating duct flows in industrial applications has become more evident. In this study a general computational method has been developed for calculating turbulent quantities in any arbitrary three dimensional duct. Four different turbulence models for predicting the turbulent Reynolds stresse
Empirical evaluations in software engineering are important in order to build a body of knowledge of methods that work in different environments. This thesis presents six empirical investigations of two techniques applied to software inspections, namely reading techniques and fault content estimation techniques. The first part of the thesis presents a series of experiments of a novel reading tech
Theories of democracy consider communicative interaction among citizens central, In recent years the idea of deliberative democracy has galvanised elements of political theory with perspectives on communication. This concept emerges to a large extent from the Habermasian trajectory and links currents from theories of civil society and citizenship. It has thus a rather forceful normative dimension.
