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The ammonothermal method is one of the most promising candidates for large-scale bulk GaN growth due to its scalability and high crystalline quality. However, emphasis needs to be put on understanding the incorporation and effects of impurities during growth. This article discusses how impurities are incorporated in different growth zones in basic ammonothermal GaN, and how they affect the structu

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Background: Overweight and obesity are widespread chronic disorders defined as excessive fat accumulation, and are major risk factors for several chronic diseases including type 2 diabetes, coronary heart disease, high blood pressure and fatty liver. Changes in lifestyle such as increased physical activity and a healthy diet can be crucial tools for treating obesity. Intake of rose hip, the fruit

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Policies aimed to spur quality competition among health care providers are ubiquitous, but their impact on quality is ex ante ambiguous. This study contributes to the sparse empirical literature on primary care quality by examining the heterogeneous impact of recent competition enhancing reforms in Sweden. The reforms led to substantially more entry of new providers in more exposed markets, but th

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Context. At about 1000 days after the launch of Gaia we present the first Gaia data release, Gaia DR1, consisting of astrometry and photometry for over 1 billion sources brighter than magnitude 20.7. Aims. A summary of Gaia DR1 is presented along with illustrations of the scientific quality of the data, followed by a discussion of the limitations due to the preliminary nature of this release. Meth

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We study the problem of decomposing a measured signal as a sum of decaying exponentials. There is a direct connection to sums of these types and positive semi-definite (PSD) Hankel matrices, where the rank of these matrices equals the number of exponentials. We propose to solve the identification problem by forming an optimization problem with a misfit function combined with a rank penalty functio

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In the EU, it is believed that the potential benefits of academic R&D are not fully reaped. Much attention is, therefore, given to enhancing commercialisation in the form of academic spin-offs, patents and licences. There are, however, a number of problems with this way of analysing the effects of academic R&D. Its contribution must instead be captured by a systems approach and we go some

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Cloud retrievals from the Moderate Resolution Imaging Spectroradiometer (MODIS) instruments aboard the satellites Terra and Aqua and the Visible Infrared Imaging Radiometer Suite (VIIRS) instrument aboard the Suomi-NPP satellite are evaluated using a combination of ground-based instruments providing vertical profiles of clouds. The ground-based measurements are obtained from the Atmospheric Radiat

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The C-terminal domain V of the basement membrane proteoglycan perlecan was previously shown to play a major role in extracellular matrix and cell interactions. A homologous sequence of 708 amino-acid residues from Drosophila has now been shown to be 33% identical to mouse perlecan domain V. It consists of three laminin G-type (LG) and epidermal growth factor-like (EG) modules but lacks the EG3 mod

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Background: The search for a biomarker of Alzheimer's disease (AD) pathology (amyloid-β (Aβ) and tau) is ongoing, with the best markers currently being measurements of Aβ and tau in cerebrospinal fluid (CSF) and via positron emission tomography (PET) scanning. These methods are relatively invasive, costly, and often have high screening failure rates. Consequently, research is aiming to elucidate b

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The behaviour of sedimenting particles depends on the dust-to-gas ratio of the fluid. Linear stability analysis shows that solids settling in the Epstein drag regime would remain homogeneously distributed in non-rotating incompressible fluids, even when dust-to-gas ratios reach unity. However, the nonlinear evolution has not been probed before. Here, we present numerical calculations indicating th

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Spatially segregated ecosystems are frequently subsidized by cross-habitat linkages, but the extent to which the functional links between habitats influence local community attributes, such as consumer and food web structure is still poorly understood. Using the bidirectional linkage between benthic and pelagic habitats in floodplain lakes, we address this important question by looking for evidenc

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Background: Indications for negative-pressure wound therapy (NPWT) in vascular surgical patients are expanding. The aim of this review was to outline the evidence for NPWT on open and closed wounds. Methods: A PubMed, EMBASE and Cochrane Library search from 2007 to June 2016 was performed combining the medical subject headings terms 'wound infection', 'abdominal aortic aneurysm (AAA)', 'fasciotomy

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Dercum’s disease is a rare disease characterized by chronic pain (>3 months) in the adipose tissue, generalized overweight, and a number of associated symptoms. The pain is often disabling and resistant to traditional analgesics. Liposuction of Dercum’s disease was first described in 1987, and two prospective controlled studies have demonstrated that it can give pain relief and improve quality of

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The dynamic properties of the actin cytoskeleton in smooth muscle cells play an important role in a number of cardiovascular disease states. The state of actin does not only mediate mechanical stability and contractile function but can also regulate gene expression via myocardin related transcription factors (MRTFs). These transcriptional co-activators regulate genes encoding contractile and cytos

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Synthesis of intercalated composites were carried out using CaAl-LDH (layered double hydroxide) as host and the anionic form of Fe(III)-amino acid complexes as guest materials. Intercalation was attempted with two methods either introducing the preformed complexes or constructing the complex among the layers of the LDH. After optimization of the synthesis parameters, structural characterization wa

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Context While vascular endothelial growth factor-targeted therapy and mammalian target of rapamycin inhibition are effective strategies in treating clear cell renal cell carcinoma (ccRCC), the most effective therapeutic approach for patients with non-clear cell RCC (non-ccRCC) is unknown. Objective To systematically review relevant literature comparing the oncological outcomes and adverse events o

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OBJECTIVE To evaluate 2 different methods of surveillance and to estimate the incidence of norovirus (NoV) outbreaks in hospitals. DESIGN Prospective observational study. SETTING All 194 hospital wards in southern Sweden during 2 winter seasons (2010-2012). METHODS Clinical surveillance based on outbreak reports of 2 or more clinical cases, with symptom onset within 5 days, was compared with labor