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Background: Subjects born with low birth weight (LBW) display a more energy-conserving response to fasting compared with normal birth weight (NBW) subjects. However, the molecular mechanisms explaining these metabolic differences remain unknown. Environmental influences may dynamically affect epigenetic marks, also in postnatal life. Here, we aimed to study the effects of short-term fasting on lep

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Simultaneously planar laser-induced fluorescence (PLIF) measurements of OH, CH, CH2O and toluene are carried out to investigate the structures of turbulent premixed methane/air jet flames in the flamelet regime and the thin-reaction zones regime. A premixed flame jet burner of an inner diameter of 1.5 mm is employed. Stoichiometric methane/air mixtures introduced as a jet are ignited and stabilize

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Agricultural intensification is a leading cause of global biodiversity loss, which can reduce the provisioning of ecosystem services in managed ecosystems. Organic farming and plant diversification are farm management schemes that may mitigate potential ecological harm by increasing species richness and boosting related ecosystem services to agroecosystems. What remains unclear is the extent to wh

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Objective: The glucose stimulation of insulin secretion (GSIS) by pancreatic β-cells critically depends on increased production of metabolic coupling factors, including NADPH. Nicotinamide nucleotide transhydrogenase (NNT) typically produces NADPH at the expense of NADH and δpH in energized mitochondria. Its spontaneous inactivation in C57BL/6J mice was previously shown to alter ATP production, Ca

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Purpose: Deficiency of interleukin-1 receptor antagonist (DIRA) is a rare life-threatening autoinflammatory disease caused by autosomal recessive mutations in IL1RN. DIRA presents clinically with early onset generalized pustulosis, multifocal osteomyelitis, and elevation of acute phase reactants. We evaluated and treated an antibiotic-unresponsive patient with presumed DIRA with recombinant IL-1Ra

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Non-native animals can encounter very different environments than those they are adapted to. Functional changes in morphology, physiology and life-history following introduction show that organisms can adapt both fast and efficiently. It remains unclear, however, if female reproductive characters and male sexually selected behaviour show the same adaptive potential. Furthermore, the invasion succe

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Protest and activism are endemic and potent features of many nations’ political life and critical potential counters to democratic backsliding and authoritarianism. In this review article, we meta-analytically examine six decades of research findings on what explains participation, focusing particularly on two well-studied protest forms: marches and demonstrations. Focusing on these iconic and com

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Shifts in dissolved organic matter (DOM) composition, caused by seasonal or episodic events, can significantly alter the removal of per- and polyfluoroalkyl substances (PFAS) by granular activated carbon (GAC). To investigate how changes in feedwater composition impact PFAS removal in aged GAC, a 20-day experiment was conducted in eight parallel small-scale columns. Columns were filled with aged G

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Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes classified into the auxiliary activity (AA) families of the CAZy database. They oxidatively cleave glycosidic bonds in recalcitrant polysaccharides, playing a key role in biomass degradation and contributing to the virulence of some pathogens. The redox state of the active-site copper and its coordination geometry are central

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This case study aims to dissect the world famous Wenzhou footwear manufacturing industry in order to discover how, if at all, the case complies with an industrial organisation framework, namely the industrial district model, which is becoming more and more prevalent in less developed countries (LDCs). In order to examine the extent to which the industrial district model may have developed and adv

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In this report, an urban water sector CDM project in Karnataka, India, is profiled as a case-study to analyse causes, effects and impacts of various barriers and to identify opportunities to overcome these barriers. The study attempts to identify key elements of a strategy for application to municipal sector CDM/EE projects both in Karnataka and in other parts of India. Like their counterparts in

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The report, designed for interested parties of the industrial food industry in France, is founded on three research questions inspired by literature studies of sustainable development, management of corporate social responsibility, industrial food production and food product quality. The research questions search for the identification and explanation of critical categories of concern relevant for

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UPPSATSEN ÄR SKRIVEN I ÄMNET TJECKISKA (KURS TJE252). The history of gender equality in the Czech Republic i's long and diverse. Thi's thesi's aim's to provide a concise mapping of it's development, with the purpose to illustrate and explain factor's that have consequence's to thi's day. The principal focu's of the study i's the civic women''s movem

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The thesis is investigating creation of Karen transnationality as a result of mass-resettlement of Karen refugees to third countries focusing on transnational identity and political, social and economic activism towards the territory of origin. The methodology used for the purpose of the study is ethnographic fieldwork, field observations, semi-structured interviews and statistical data. The poten

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Language is a powerful tool in the creation of social identities. This work analyses the security policy discourses of two major actors in world politics: the European Union and the United States. The material is composed of security documents of both actors ranging from the time before the 9/11 terrorist attacks to present day. Discourse analysis, especially its Foucauldian strand emphasising the

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The aim of this phenomenological study was to explore what role teachers at introductory programmes (SFI-schools) play in the integration of immigrants, how the teachers experience their work and what they feel about the situation in which their students, the immigrants, are. To what extent and in what way do the teachers contribute to facilitating the integration of the immigrant students? The s

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This essay aims to estimate the cost of hospitalisation in 2003 for Region Skåne for diseases fully attributable to alcohol. An included review of cost-of-illness studies of societal costs of alcohol misuse reaches the conclusions that comparability between studies has increased in recent years as a result, among others, of the establishing of international guidelines. Despite this, some problems

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The purpose of this case study is to identify the driving forces that motivated various companies to implement sustainable water management (SWM) voluntary initiatives in four Latin American countries: Panama, Colombia, Ecuador and Brazil. Additionally, the case study explores opportunities on how strategic stakeholders, such as government institutions, NGOs, IGOs, financing institutions, and the